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John S. Werner, Ph.D.
Distinguished Professor
Locations and Contact
Lawrence J. Ellison Ambulatory Care Center
Ophthalmology Clinic-Eye Center
4860 Y St.
Sacramento, CA 95817
Phone: 916-734-6602
Clinical Interests
Dr. Werner studies the neurophysiological computations and mechanisms that mediate human vision, particularly changes in color and spatial vision across the life span and in association with retinal and optic nerve disease.
His work has demonstrated adaptive modifications of the visual system response to changes in signals due to aging of the eye's optics and retina. His laboratory has developed state-of-the-art methods for imaging the human retina of the living eye at a cellular scale.
Research/Academic Interests
Dr. Werner's research is concerned with the neurophysiological computations and mechanisms that mediate human vision, particularly changes in vision across the life span and in diseases of the retina and optic nerve. His studies use psychophysical and electrophysiological methods, together with high-resolution retinal imaging (adaptive optics and optical coherence tomography), to study both normal aging and age-related diseases leading to blindness.
Division
Ophthalmology
Center/Program Affiliation
Undergraduate School
B.A., Human Development, University of Kansas, Lawrence KS 1974
Other School
Ph.D., Experimental Psychology, Brown University, Providence RI 1979
Other School
M.A., Human Development, University of Kansas, Lawrence KS 1974
Fellowship
Instituut voor Zintuigfysiologie - TNO (Institute for Perception), Soesterberg, The Netherlands 1979
Fellowship
Universitat Freiburg, Abteilung fur Neurophysiologie, Freiburg, i, Br., Germany 1981
Verriest Medal, International Colour Vision Society, 2015
Pisart Vision Award, Lighthouse International (New York), 2008
Jules and Doris Stein Research to Prevent Blindness Professorship, 2000
Ninetieth Annual Distinguished Research Lecture, University of Colorado, 1998
Alexander von Humboldt Foundation, Humboldt-Preis, 1994
Werner JS, Marsh-Armstrong B, Knoblauch K. Adaptive Changes in Color Vision from Long-Term Filter Usage in Anomalous but Not Normal Trichromacy. Curr Biol. 2020 Aug 3;30(15):3011-3015.e4. doi:10.1016/j.cub.2020.05.054. Epub 2020 Jun 25. PMID: 32589909.
Malania M, Konrad J, Jägle H, Werner JS, Greenlee MW. Compromised integrity of central visual pathways in patients with macular degeneration. Investigative Ophthalmology & Visual Science. 2017 Jun;58: 2939-2947. doi:10.1167/iovs.16-21191.
Webster MA, Halen K, Meyers AJ, Winkler P, Werner JS. Color appearance and compensation in the near periphery. Proceedings of the Royal Society B Biological Sciences. 2010;277:1817-1825. doi:10.1098/rspb.2009.1832.
Werner JS, Chalupa LM (Eds.) The New Visual Neurosciences, MIT Press Cambridge MA. 2014.
Werner JS. The Verriest Lecture: Short-wave-sensitive cone pathways across the life span. J Opt Soc Am A Opt Image Sci Vis. 2016 Mar;33(3):A104-22. doi:10.1364/JOSAA.33.00A104. PMID:26974914.
Schwartz DM, Fingler J, Kim DY, Zawadzki RJ, Morse LS, Park SS, Fraser SE, Werner JS. Phase-variance optical coherence tomography: a technique for noninvasive angiography. Ophthalmology. 2014 Jan;121(1):180-187. doi:10.1016/j.ophtha.2013.09.002. Epub 2013 Oct 21. PMID:24156929.
Kim DY, Fingler J, Zawadzki RJ, Park SS, Morse LS, Schwartz DM, Fraser SE, Werner JS. Optical imaging of the chorioretinal vasculature in the living human eye. Proc Natl Acad Sci U S A. 2013 Aug 27;110(35):14354-9. doi.org/10.1073/pnas.1307315110.
Panorgias A, Zawadzki RJ, Capps AG, Hunter AA, Morse LS, Werner JS. Multimodal assessment of microscopic morphology and retinal function in patients with geographic atrophy. Invest Ophthalmol Vis Sci. 2013 Jun 26;54(6):4372-84. doi:10.1167/iovs.12-11525. PMID:23696601.
Shinomori K, Werner JS. Aging of human short-wave cone pathways. Proc Natl Acad Sci U S A. 2012 Aug 14;109(33):13422-7. doi:10.1073/pnas.1119770109. Epub 2012 Jul 30. PMID:22847416.