Nancy E. Lane, M.D. for UC Davis Health

Nancy E. Lane, M.D.

Distinguished Professor of Medicine and Rheumatology

To see if Nancy E. Lane is accepting new patients, or for assistance finding a UC Davis doctor, please call 800-2-UCDAVIS (800-282-3284).



Rheumatology, Allergy and Clinical Immunology


Internal Medicine

Locations and Contact

Lawrence J. Ellison Ambulatory Care Center

General Internal Medicine
4860 Y St.
Sacramento, CA 95817

Get Directions

Phone: 916-734-2737

Additional Numbers

Physician Referrals

800-4-UCDAVIS (800-482-3284)

Philosophy of Care

Dr. Lane takes the time to listen to each patient and develop a treatment plan that is appropriate for them.

Clinical Interests

Dr. Lane is a rheumatologists who has expertise for diseases in adults that are from osteoarthritis, osteoporosis, general rheumatology, she has special expertise in disease of bone including osteogenesis imperfecta, and glucocorticoid induced osteoporosis, and pain related to osteoarthritis.

Research/Academic Interests

Dr. Lane does research in the etiology of osteoporosis in the elderly, glucocorticoid induced osteoporosis and understanding muscle in patients with osteoarthritis and treatments for osteoarthritis.


Rheumatology, Allergy and Clinical Immunology

Undergraduate School

B.S., UC Davis, Davis CA 1976

Medical School

M.D., UC San Francisco School of Medicine, San Francisco CA 1980


UC San Francisco/Mt. Zion, San Francisco CA 1980-1981


UC San Francisco/Mt. Zion, San Francisco CA 1981-1983


Rheumatology, Stanford University Medical Center and VA Hospital, Palo Alto CA 1983-1986

Wise BL, Seidel MF, Lane NE. The evolution of nerve growth factor inhibition in clinical medicine. Nat Rev Rheumatol. 2021 Jan;17(1):34-46. doi:10.1038/s41584-020-00528-4. Epub 2020 Nov 20. PMID:33219344.

Wilmanski T, Diener C, Rappaport N, Patwardhan S, Wiedrick J, Lapidus J, Earls JC, Zimmer A, Glusman G, Robinson M, Yurkovich JT, Kado DM, Cauley JA, Zmuda J, Lane NE, Magis AT, Lovejoy JC, Hood L, Gibbons SM, Orwoll ES, Price ND. Gut microbiome pattern reflects healthy ageing and predicts survival in humans. Nat Metab. 2021 Feb;3(2):274-286. doi:10.1038/s42255-021-00348-0. Epub 2021 Feb 18. Erratum in: Nat Metab. 2021 Apr;3(4):586. PMID:33619379.

Zeng C, Lane NE, Li X, Wei J, Lyu H, Shao M, Lei G, Zhang Y. Association between bariatric surgery with long-term analgesic prescription and all-cause mortality among patients with osteoarthritis: a general population-based cohort study. Osteoarthritis Cartilage. 2021 Oct;29(10):1412-1417. doi:10.1016/j.joca.2021.05.063. Epub 2021 Jul 19. PMID:34293442.

Yazici Y, McAlindon TE, Gibofsky A, Lane NE, Lattermann C, Skrepnik N, Swearingen CJ, Simsek I, Ghandehari H, DiFrancesco A, Gibbs J, Tambiah JRS, Hochberg MC. A Phase 2b randomized trial of lorecivivint, a novel intra-articular CLK2/DYRK1A inhibitor and Wnt pathway modulator for knee osteoarthritis. Osteoarthritis Cartilage. 2021 May;29(5):654-666. doi:10.1016/j.joca.2021.02.004. Epub 2021 Feb 12. PMID:33588087.

Senders A, Bauer SR, Chen Y, Oken B, Fink HA, Lane NE, Sajadi KP, Marshall LM, For The Osteoporotic Fractures In Men MrOS Study Group. Lower urinary tract symptoms are associated with musculoskeletal pain among older men: Preliminary evidence for central sensitization as a mechanism? Neurourol Urodyn. 2021 Nov;40(8):1929-1938. doi:10.1002/nau.24767. Epub 2021 Aug 15. PMID:34396562.

Lane NE, Saag K, O'Neill TJ, Manion M, Shah R, Klause U, Eastell R. Correction to: Real-world bone turnover marker use: impact on treatment decisions and fracture. Osteoporos Int. 2021 Mar;32(3):609. doi:10.1007/s00198-021-05828-3. Erratum for: Osteoporos Int. 2020 Nov 24. PMID:33464393.

Joseph GB, Ramezanpour S, McCulloch CE, Nevitt MC, Lynch J, Lane NE, Pedoia V, Majumdar S, Link TM. Weight Cycling and Knee Joint Degeneration in Individuals with Overweight or Obesity: Four-Year Magnetic Resonance Imaging Data from the Osteoarthritis Initiative. Obesity (Silver Spring). 2021 May;29(5):909-918. doi:10.1002/oby.23129. Epub 2021 Apr 1. PMID:33797183.

McNulty MJ, Xiong YM, Yates K, Karuppanan K, Hilzinger JM, Berliner AJ, Delzio J, Arkin AP, Lane NE, Nandi S, McDonald KA. Molecular pharming to support human life on the moon, mars, and beyond. Crit Rev Biotechnol. 2021 Sep;41(6):849-864. doi:10.1080/07388551.2021.1888070. Epub 2021 Mar 9. PMID:33715563.

Ensrud KE, Schousboe JT, Kats AM, Vo TN, Taylor BC, Cawthon PM, Cauley JA, Lane NE, Hoffman AR, Langsetmo L; Osteoporotic Fractures in Men (MrOS) Research Group. Height Loss in Old Age and Fracture Risk Among Men in Late Life: A Prospective Cohort Study. J Bone Miner Res. 2021 Jun;36(6):1069-1076. doi:10.1002/jbmr.4278. Epub 2021 Mar 19. PMID:33617678.

Xiao Q, Qian J, Evans DS, Redline S, Lane NE, Ancoli-Israel S, Scheer FAJL, Stone K. Cross-Sectional and Prospective Associations of Rest-Activity Rhythms With Circulating Inflammatory Markers in Older Men. J Gerontol A Biol Sci Med Sci. 2022 Jan 7;77(1):55-65. doi:10.1093/gerona/glab095. PMID:33822930.