Murray B. Gardner (1982 - 1990)
Murray Gardner had a background in General Practice and General Pathology before embarking on a research career at USC on oncogenic retroviruses in human and animal cancer. At UC Davis he helped to build an interdisciplinary team of investigators in the Medical and Veterinary Schools to study immunosuppressive retroviruses in human and monkey AIDS.
Archived content
- Contributions of UC Davis Schools of Veterinary and Human Medicine to the Early Years of the AIDS Pandemic: 1981-1994
- An Unbelievable Mid-Career Opportunity
- Genesis of the Center for Comparative Medicine (CCM) at UC Davis
- A Research Career Twice Rescued by Retroviruses
- Collecting Pituitary Glands at Autopsies , Monkeys at UC Davis and the History of Prions
- Tomato Mosaic Virus: ”The Typhoid Mary of Plants“ and Me
- My Introduction to Veterinary Pathology
- EBV and Me
- Turning Our Urban Home Into An Urban Farm
- History of the Edmondson Summer Research Fellowship Program
Gallery of Images
1960s
My research during this period was applied mainly to describing the effects of Los Angeles ambient air ( smog ) upon the lungs of exposed lab mice and rats. A few papers describe ultrastructural features in miscellaneous human tissues as seen in the electron microscope which was a new tool at that time.
1970s to mid 1980s
Papers in this time period , when I was at the University of Southern California, describe my experience uncovering the natural history of oncogenic retroviruses in wild mice , rats and domestic cats while searching unsuccessfully for these agents in humans.
Year |
Location |
Type |
Synopsis |
| 1971 | USC | Gardner MB, Rongey RW, Johnson EY, DeJournett R, Huebner RJ. "C-type tumor virus particles in salivary tissue of domestic cats." J Natl Cancer Inst. 1971 Sep;47(3):561-8. PMID: 5157577. |
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| 1971 | USC | RESEARCH | Gardner MB, Officer JE, Rongey RW, Estes JD, Turner HC, Huebner RJ. "C-type RNA tumour virus genome expression in wild house mice." Nature. 1971 Aug 27;232(5313):617-20. doi: 10.1038/232617a0. PMID: 4328548. |
| 1973 | USC | Gardner MB, Henderson BE, Estes JD, Menck H, Parker JC, Huebner RJ. "Unusually high incidence of spontaneous lymphomas in wild house mice." J Natl Cancer Inst. 1973 Jun;50(6):1571-9. doi: 10.1093/jnci/50.6.1571. PMID: 4352203. |
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| 1973 | "" | Officer JE, Tecson N, Estes JD, Fontanilla E, Rongey RW, Gardner MB. "Isolation of a neurotropic type C virus." Science. 1973 Sep 7;181(4103):945-7. doi: 10.1126/science.181.4103.945. PMID: 4354228. |
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| 1973 | "" | Roy-Burman P, Rongey RW, Henderson BE, Gardner MB. "Attempts to detect RNA tumour virus in human milk." Nat New Biol. 1973 Aug 1;244(135):146. doi: 10.1038/newbio244146a0. PMID: 4125043. |
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| 1974 | "" | Gardner MB, Henderson BE, Officer JE, Rongey RW, Parker JC, Oliver C, Estes JD, Huebner RJ. "A spontaneous lower motor neuron disease apparently caused by indigenous type-C RNA virus in wild mice." J Natl Cancer Inst. 1973 Oct;51(4):1243-54. doi: 10.1093/jnci/51.4.1243. PMID: 4355605; PMCID: PMC7204280. |
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| 1974 | "" | REVIEW | Gardner MB, Henderson BE, Estes JD, Rongey RW, Casagrande J, Pike M, Huebner RJ. "The epidemiology and virology of C-type virus-associated hematological cancers and related diseases in wild mice." Cancer Res. 1976 Feb;36(2 pt 2):574-81. PMID: 175918. |
| 1976 | "" | Gardner MB, Klement V, Henderson BE, Meier H, Estes JD, Huebner RJ. "Genetic control of type C virus of wild mice." Nature. 1976 Jan 15;259(5539):143-5. doi: 10.1038/259143a0. PMID: 174006. |
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| 1977 | "" | REVIEW | Gardner, MB…. Huebner RJ "Search for RNA Tumor Virus in Humans" Cold Spring Harbor Conference on Cell Proliferation, Vol 4 , Origins of Human Cancer HH Hiatt ( ed ) Cold Spring Harbor Laboratory ,1235-1251 1977 |
| 1978 | "" | Rasheed S, Gardner MB, Huebner RJ. "In vitro isolation of stable rat sarcoma viruses." Proc Natl Acad Sci U S A. 1978 Jun;75(6):2972-6. doi: 10.1073/pnas.75.6.2972. PMID: 208081; PMCID: PMC392689. |
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| 1978 | "" | Rasheed S, Charman HP, Gardner MB. "Wild rat type C virus: isolation and characterization." Virology. 1978 Sep;89(2):605-9. doi: 10.1016/0042-6822(78)90201-5. PMID: 82291. |
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| 1980 | "" | Gardner, Murray. (1980). "Chapter 1. Historical Background." 10.1016/B978-0-12-666050-0.50036-4. |
1980 to 2015
In this era , at UC Davis, my research papers feature the discovery, natural history , pathogenesis and prevention of immunosuppressive retroviruses as causes of AIDS in man, macaques and domestic cats.
Year |
Location |
Type |
Synopsis |
| 1983 | UC Davis | RESEARCH | Henrickson RV, Maul DH, Osborn KG, Sever JL, Madden DL, Ellingsworth LR, Anderson JH, Lowenstine LJ, Gardner MB. "Epidemic of acquired immunodeficiency in rhesus monkeys." Lancet. 1983 Feb 19;1(8321):388-90. doi: 10.1016/s0140-6736(83)91503-9. PMID: 6130381. |
| 1984 | "" | Marx PA, Maul DH, Osborn KG, Lerche NW, Moody P, Lowenstine LJ, Henrickson RV, Arthur LO, Gilden RV, Gravell M, et al. "Simian AIDS: isolation of a type D retrovirus and transmission of the disease." Science. 1984 Mar 9;223(4640):1083-6. doi: 10.1126/science.6695196. PMID: 6695196. |
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| 1985 | "" | Gardner MB. "Retroviral spongiform polioencephalomyelopathy." Rev Infect Dis. 1985 Jan-Feb;7(1):99-110. doi: 10.1093/clinids/7.1.99. PMID: 2984760. |
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| 1989 | "" | Gardner, Murray & Luciw, Paul. (1990). "Animal Models of Aids." FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 3. 2593-606. 10.1096/fasebj.3.14.2556312. |
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| 1995 | "" | Yamamoto JK, Hohdatsu T, Olmsted RA, Pu R, Louie H, Zochlinski HA, Acevedo V, Johnson HM, Soulds GA, Gardner MB. "Experimental vaccine protection against homologous and heterologous strains of feline immunodeficiency virus." J Virol. 1993 Jan;67(1):601-5. doi: 10.1128/JVI.67.1.601-605.1993. PMID: 8380095; PMCID: PMC237403. |
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| 2002 | "" | Gardner MB "Mammary Tumor Viruses in Wild Mice 1 and Humans" Comparative Medicine 52, 19-20, 2002 |
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| 2008 | "" | Gardner MB, Luciw PA. "Macaque models of human infectious disease." ILAR J. 2008;49(2):220-55. doi: 10.1093/ilar.49.2.220. PMID: 18323583; PMCID: PMC7108592. |
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| 2016 | "" | Gardner M. "A historical perspective: Simian AIDS-an accidental windfall." J Med Primatol. 2016 Oct;45(5):212-4. doi: 10.1111/jmp.12234. Epub 2016 Sep 19. PMID: 27640332. |
Because I led large research teams at USC and UC Davis, my papers reflect the contribution of many colleagues. I wrote 38 Review papers which testify to my proclivity to synthesize the science in my field of research, a result of my general practice medical training.
