Paul G. FitzGerald, Ph.D.
Chair and Distinguished Porfessor, Department of Cell Biology and Human Anatomy
Locations and Contact
Additional Numbers
Clinic Phone
Research/Academic Interests
Our program studies the role of intermediate filaments in cell biology, with an emphasis on their contribution to the biology of the ocular lens.
Division
Cell Biology and Human Anatomy
Undergraduate School
B.A., Physiolohy, UC Berkeley, Berkeley CA 1974
Other School
Ph.D., Cell Biology/Anatomy, UCLA, Los Angeles CA 1982
Fellowship
Neurobiology, Harvard Medical School, Boston MA 1982-1984
Zhang P, Shibata B, Peinado G, Zawadzki RJ, FitzGerald P, Pugh EN Jr. Measurement of Diurnal Variation in Rod Outer Segment Length In Vivo in Mice With the OCT Optoretinogram. Invest Ophthalmol Vis Sci. 2020 Mar 9;61(3):9. doi:10.1167/iovs.61.3.9. PMID:32176260.
Gae DD, Budamagunta MS, Hess JF, McCarrick RM, Lorigan GA, FitzGerald PG, Voss JC. Completion of the Vimentin Rod Domain Structure Using Experimental Restraints: A New Tool for Exploring Intermediate Filament Assembly and Mutations. Structure. 2019 Oct 1;27(10):1547-1560.e4. doi:10.1016/j.str.2019.07.011.
Gerhart J, Behling K, Paessler M, Milton L, Bramblett G, Garcia D, Pitts M, Hurtt R, Crawford M, Lackman R, Nguyen D, Infanti J, FitzGerald P, George-Weinstein M. Rhabdomyosarcoma and Wilms tumors contain a subpopulation of noggin producing, myogenic cells immunoreactive for lens beaded filament proteins. PLoS One. 2019 Apr 11;14(4):e0214758. doi:10.1371/journal.pone.0214758. PMID:30973903.
Kim S, Thomasy SM, Raghunathan VK, Teixeira LBC, Moshiri A, FitzGerald P, Murphy CJ. Ocular phenotypic consequences of a single copy deletion of the Yap1 gene (Yap1 (+/-)) in mice. Mol Vis. 2019 Feb 17;25(1):129-142.
Budamagunta MS, Guo F, Sun N, Shibata B, FitzGerald PG, Voss JC, Hess JF. Production of recombinant human tektin 1, 2, and 4 and in vitro assembly of human tektin 1. Cytoskeleton (Hoboken). 2018 Jan;75(1):3-11. doi:10.1002/cm.21418. Epub 2017 Dec 2. PMID:29108134.
Gerhart J, Withers C, Gerhart C, Werner L, Mamalis N, Bravo-Nuevo A, Scheinfeld V, FitzGerald P, Getts R, George-Weinstein M. Myo/Nog cells are present in the ciliary processes, on the zonule of Zinn and posterior capsule of the lens following cataract surgery. Exp Eye Res. 2018 Jun;171:101-105. doi:10.1016/j.exer.2018.03.016. Epub 2018 Mar 17. PMID: 29559302.
Cheng C, Nowak RB, Biswas SK, Lo WK, FitzGerald PG, Fowler VM. Tropomodulin 1 Regulation of Actin Is Required for the Formation of Large Paddle Protrusions Between Mature Lens Fiber Cells. Invest Ophthalmol Vis Sci. 2016 Aug 1;57(10):4084-99. doi:10.1167/iovs.16-19949. PMID:27537257.
Sun N, Shibata B, Hess JF, FitzGerald PG. An alternative means of retaining ocular structure and improving immunoreactivity for light microscopy studies. Mol Vis. 2015 Apr 16;21:428-42. PMID:25991907.
Sindhu Kumari S, Gupta N, Shiels A, FitzGerald PG, Menon AG, Mathias RT, Varadaraj K. Role of Aquaporin 0 in lens biomechanics. Biochem Biophys Res Commun. 2015 Jul 10;462(4):339-45. doi:10.1016/j.bbrc.2015.04.138. Epub 2015 May 8. PMID:25960294.
Ofri R, Reilly CM, Maggs DJ, Fitzgerald PG, Shilo-Benjamini Y, Good KL, Grahn RA, Splawski DD, Lyons LA. Characterization of an Early-Onset, Autosomal Recessive, Progressive Retinal Degeneration in Bengal Cats. Invest Ophthalmol Vis Sci. 2015 Aug;56(9):5299-308. doi:10.1167/iovs.15-16585. PMID:26258614.