Philosophy of Care
Dr. Zhang has a personalized approach to aid each patient. With attentive supervision to patients neurological response, he uniquely designs each patients care plan to achieve their best quality of symptom management, believing that this will improve their quality of life.
Dr. Zhang's clinical and research interests focus primarily on Parkinson's disease, including its epidemiology and the association between past nutritional deficiency and current prevalence of the disease. He is testing new drugs and gene therapy with neuroprotective properties that may slow down the progression of Parkinson's. Dr. Zhang’s practice also specializes in functional neurology focusing on the implantation and management of deep brain stimulation. He is well versed in latest research in neuromodulation, and oversees the DBS candidacy evaluation to postsurgery programming proccess. He works extensively with national and international collaborators in translational research in neurodegeneration and fellowship training programs. He is investigating the clinical manifestation of the disease in patients with atypical Parkinson's disease, and those with a family history of pre-mutation for fragile X syndrome, a genetic disorder that typically affects children. Additionally, Dr. Zhang specializes in botulinum toxin (Botox) treatments for a variety of conditions, including, but not limited to, dystonia, spasticity and tremor. He uses electric muscle testing when giving Botox injections to improve accuracy and gain maximal results.
As a fellowship trained neurologist sub-specializing in movement disorders and Experimental Therapeutics, Dr. Zhang has a primary clinical and research interest in Parkinson's disease (PD). He also has a related interest in neuromodulation with Deep Brain Stimulation therapy.
M.D., Beijing Medical University, Beijing, China 1983
Ph.D., Tulane University, New Orleans LA 1994
Internship: Neurology, Cleveland Clinic Foundation, Cleveland OH 1994-1995
Internship: Interdisciplinary Studies: English, Texas Tech University, Lubbock TX 1986-1987
Internal Medicine, Beijing Medical College, Beijing, China 1984-1985
Neurology, Cleveland Clinic Foundation, Cleveland OH 1996-1998
Movement Disorders and Experimental Therapeutics, University of Rochester, Rochester NY 1998-2000
American Board of Neurology and Psychiatry,
Medical Board of California,
American Academy of Neurology
Chinese American Medical Association of California
International Congress of Movement Disorders
Movement Disorders Society
Society of Chinese American Physicians of Entrepreneurs
Honors and Awards
Citris Inaugural Seed Fund Award: Robotic Exoskeleton For The Stabilization Of Tremors (RST) In the Hand and Wrist, 2016
Visiting scholar of University of California to China, Sponsored by UC Office of President under 10+10 Program to Shanghai China to present at the annual Neuroscience symposium, 2006
Visiting Professor, Movement Disorder Society, USA, 2006
Roche Movement Disorders Research Award, 1997
Tulane Graduate School Traveling Award, Graduate Student Excellence in Research, 1992, 1993
Select Recent Publications
Hall DA, Stebbins GT, Jacquemont S, Berry-Kravis E, Goetz CG, Hagerman R, Zhang L, Leehey MA. Clinimetric Properties of the Fragile X-associated. 2019.
Wang XH, Yang JC, Soohoo R, Cotter D, Yuan M, Xia J, Yaqub S, Doty J, Niu YQ, Tassone F, Hagerman R, Zhang L, Olichney J. Cognitive Deficits and Associated ERP N400 Abnormalities in FXTAS With Parkinsonism. Front Genet. 2018;9:327.
Sperry L, Zhang L, Shahlaie K. DBS in the Management of Dystonia Beyond the Word of Neurotoxins. American Association of Nurse Life Care Planners. 2018;17(4):15-19.
Scangos KW, Carter CS, Gurkoff G, Zhang L, Shahlaie K. A pilot study of subthalamic theta frequency deep brain stimulation for cognitive dysfunction in Parkinson's disease. Brain Stimulation. 2017;11(2);456-458.
Yuan M, Malhado-Chang N, Sperry L, Farias S, O'Conner K, Shahlaie K, Wheelock V, Zhang L. Atypical Antipsychotic Therapy in Parkinson’s Disease Psychosis: A Retrospective Study. Brain and Behavior. 2017;7(6).
Trenkwalder C, Berg D, Rascol O, Eggert K, Ceballos-Baumann A, Corvol JC, Storch A, Zhang L, Azulay JP, Broussolle E, Defebvre L, Geny C, Gostkowski M, Stocchi F, Tranchant C, Derkinderen P, Durif F, Espay AJ, Feigin A, Houeto JL, Schwarz J, Di Paolo T, Feuerbach D, Hockey HU, Jaeger J, Jakab A, Johns D, Linazasoro G, Maruff P, Rozenberg I, Sovago J, Weiss M, Gomez-Mancilla B. A Placebo-Controlled Trial of AQW051 in Patients with Moderate to Severe Levodopa-Induced Dyskinesia. Movement Disorders. 2016;31(7):1049-1054.
Sperry L, Zhang L, Shahaie K. Deep Brain Stimulation in the management of Chronic Pain. American Association of Nurse Life Care Planners. 2016;XVI(1):34-38.
Wang XH, Zhang L, Sperry L, Olichney J, Farias S, Shalaie K, Malhado-Chang N, Liu Y, Wang SP, Wang C. Target Selection Recommendations Based on Impact of Deep Brain Stimulation Surgeries on non-motor symptoms of Parkinson's disease. Chinese Medical Journal. 2015;128(24):3371-3380.
Liu Y, Fan JH, Gao X, Ma L1, Qiao YL, Zhang L. The Natural Progression of Parkinson's Disease in a Small Cohort with 15 Drug- naïve Patients. China Medicine Journal. 2015;128(13):1761-1764.
Zhang L, Sukharev D, Schneider A, Olichney JM, Seritan A, Hagerman RJ. Case report: Dystonia in a fragile X carrier. Mov Disord. 2014 Jun;29(7):E4-5.