Helene G. Margolis, M.A., Ph.D. for UC Davis Health

Helene G. Margolis, M.A., Ph.D.

Associate Adjunct Professor, Department of Internal Medicine



Environmental Health

Climate and Health

Chronic Disease Management


Health Policy

Population Health


Internal Medicine

Locations and Contact

Research/Academic Interests

Dr. Margolis’ transdisciplinary research seeks to define and address the diverse clinical and population health impacts of climate change-mediated environmental and psychosocial stressors, especially among medically and socially vulnerable patients and populations. Translation of her research includes informing health and public policy, and education outreach to diverse audiences to share strategies for climate change adaptation and health protection. She is also focused on developing medical education curricula for medical students and clinicians so they are prepared to prevent and/or manage the clinical and population health consequences of climate change-mediated stressors. 


General Medicine

Center/Program Affiliation

Center for Health Services Research in Primary Care
UC Davis Children's Hospital

Undergraduate School

B.A., Marine Sciences/General Biology, Southampton College, Long Island University, Southampton NY 1972

Other School

M.A., Immunology/Biology, California State University, Sacramento CA 1985

Other School

Ph.D., Epidemiology, UC Davis, Davis CA 2003

Faculty Fellow, UC Davis John Muir Institute of the Environment, 2018

Superior Accomplishment Award, State of California, Air Resources Board, 2000

Switzer Environmental Fellowship, Switzer Foundation, San Francisco CA, 1998, 1999

Floyd and Mary Schwall Medical Research Fellowship, UC Davis, 1998, 1999

Sustained Superior Accomplishment Award, State of California, Air Resources Board, 1993

Pascal M, Margolis HG, Etzel RA. Greening the International Society for Environmental Epidemiology. Epidemiology. 2021 Jul 1;32(4):466-468. doi:10.1097/EDE.0000000000001355. PMID:33788794.

Mann JK, Lutzker L, Holm SM, Margolis HG, Neophytou AM, Eisen EA, Costello S, Tyner T, Holland N, Tindula G, Prunicki M, Nadeau K, Noth EM, Lurmann F, Hammond SK, Balmes JR. Traffic-related air pollution is associated with glucose dysregulation, blood pressure, and oxidative stress in children. Environ Res. 2021 Apr;195:110870. doi:10.1016/j.envres.2021.110870. Epub 2021 Feb 12. PMID:33587949. 

Nicastro T, Teherani A, Margolis HG, Weiser S. Integrating Climate Change, the Environment, and Sustainability Themes Into Professional Health Sciences Courses: A Case Study Across a University System. Pinkerton KE, Rom WN (eds.). Climate Change and Global Public Health, Springer Nature Switzerland AG. 2020 Nov 24;28:565-582, doi:10.1007/978-3-030-54746-2_28.

Wong JYY, Margolis HG, Machiela M, Zhou W, Odden MC, Psaty BM, Robbins J, Jones RR, Rotter JI, Chanock SJ, Rothman N, Lan Q, Lee JS. Outdoor air pollution and mosaic loss of chromosome Y in older men from the Cardiovascular Health Study. Environ Int. 2018 Jul;116:239-247. doi:10.1016/j.envint.2018.04.030. Epub 2018 Apr 24. PMID:29698900.

Margolis HG, Mann JK, Lurmann FW, Mortimer KM, Balmes JR, Hammond SK, Tager IB. Altered pulmonary function in children with asthma associated with highway traffic near residence. Int J Environ Health Res. 2009 Apr;19(2):139-55. doi:10.1080/09603120802415792. PMID:19370464.

Gauderman WJ, Avol E, Gilliland F, Vora H, Thomas D, Berhane K, McConnell R, Kuenzli N, Lurmann F, Rappaport E, Margolis H, Bates D, Peters J. The effect of air pollution on lung development from 10 to 18 years of age. N Engl J Med. 2004 Sep 9;351(11):1057-67. doi:10.1056/NEJMoa040610. Erratum in: N Engl J Med. 2005 Mar 24;352(12):1276. PMID:15356303.

McConnell R, Berhane K, Gilliland F, London SJ, Islam T, Gauderman WJ, Avol E, Margolis HG, Peters JM. Asthma in exercising children exposed to ozone: a cohort study. Lancet. 2002 Feb 2;359(9304):386-91. doi:10.1016/S0140-6736(02)07597-9. Erratum in: Lancet 2002 Mar 9;359(9309):896. PMID:11844508.

Margolis HG. Heat Waves and Rising Temperatures: Human Health Impacts and the Determinants of Vulnerability. Pinkerton KE, Rom WN (eds.). Climate Change and Global Public Health, Springer Nature Switzerland AG. 2020 Nov 24;7:123-161. doi:10.1007/978-3-030-54746-2_7.

Eckel SP, Louis TA, Chaves PH, Fried LP, Margolis AH. Modification of the association between ambient air pollution and lung function by frailty status among older adults in the Cardiovascular Health Study. Am J Epidemiol. 2012 Aug 1;176(3):214-23. doi:10.1093/aje/kws001. Epub 2012 Jul 18. PMID:22811494.

Knowlton K, Rotkin-Ellman M, King G, Margolis HG, Smith D, Solomon G, Trent R, English P. The 2006 California heat wave: impacts on hospitalizations and emergency department visits. Environ Health Perspect. 2009 Jan;117(1):61-7. doi:10.1289/ehp.11594. Epub 2008 Aug 22. PMID:19165388.