Medical School

M.D., Hebei Medical University, Shijiazhuang, Hebei, China 2000

Other School

Ph.D., Cell Biology, University of Science and Technology of China, Hefei, Anhui, China 2007

Fellowship

Internal Medicine, UC Davis School of Medicine, Davis CA 2007-2015

AASLD Foundation Gupta Family Pilot Research Award in PSC, American Association for the Study of Liver Disease, 2020

Academic Federation Innovative Development Awards, UC Davis, 2020

COVID-19 Research Accelerator Fund, UC Davis, 2020

PBC Fund for the Cure Award, American Liver Foundation, 2018

Pinnacle Research Award, American Association for the Study of Liver Disease, 2017

Chang WH, Hsu SW, Zhang J, Li JM, Yang DD, Chu CW, Yoo EE, Zhang W, Yu SL, Chen CH. MTAP deficiency contributes to immune landscape remodelling and tumour evasion. Immunology. 2023 Feb;168(2):331-345. doi:10.1111/imm.13587. Epub 2022 Oct 11. PMID:36183155.

Adams DE, Heuer LS, Rojas M, Zhang W, Ridgway WM. Mutated Pkhd1 alone is sufficient to cause autoimmune biliary disease on the nonobese diabetic (NOD) genetic background. Immunogenetics. 2023 Feb;75(1):27-37. doi:10.1007/s00251-022-01276-3. Epub 2022 Sep 13. PMID:36097289.

Shao T, Leung PSC, Zhang W, Tsuneyama K, Ridgway WM, Young HA, Shuai Z, Ansari AA, Gershwin ME. Treatment with a JAK1/2 inhibitor ameliorates murine autoimmune cholangitis induced by IFN overexpression. Cell Mol Immunol. 2022 Oct;19(10):1130-1140. doi:10.1038/s41423-022-00904-y. Epub 2022 Aug 30. PMID:36042351.

Zhang W, Shao T, Leung PSC, Tsuneyama K, Heuer L, Young HA, Ridgway WM, Gershwin ME. Dual B-cell targeting therapy ameliorates autoimmune cholangitis. J Autoimmun. 2022 Oct;132:102897. doi:10.1016/j.jaut.2022.102897. Epub 2022 Aug 24. PMID:36029718.

Liu B, Yang GX, Sun Y, Tomiyama T, Zhang W, Leung PSC, He XS, Dhaliwal S, Invernizzi P, Gershwin ME, Bowlus CL. Decreased CD57 expression of natural killer cells enhanced cytotoxicity in patients with primary sclerosing cholangitis. Front Immunol. 2022 Aug 17;13:912961. doi:10.3389/fimmu.2022.912961. PMID:36059513.

Yang Y, Choi J, Chen Y, Invernizzi P, Yang G, Zhang W, Shao TH, Jordan F, Nemeria NS, Coppel RL, Ridgway WM, Kurth M, Ansari AA, Leung PSC, Gershwin ME. E. coli and the etiology of human PBC: Antimitochondrial antibodies and spreading determinants. Hepatology. 2022 Feb;75(2):266-279. doi:10.1002/hep.32172. Epub 2021 Dec 12. PMID:34608663.

Chen Z, Zhang W, Selmi C, Ridgway WM, Leung PSC, Zhang F, Gershwin ME. The myristoylated alanine-rich C-kinase substrates (MARCKS): A membrane-anchored mediator of the cell function. Autoimmun Rev. 2021 Nov;20(11):102942. doi:10.1016/j.autrev.2021.102942. Epub 2021 Sep 10. PMID:34509657.

Itoh A, Adams D, Huang W, Wu Y, Kachapati K, Bednar KJ, Leung PSC, Zhang W, Flavell RA, Gershwin ME, Ridgway WM. Enoxacin Up-Regulates MicroRNA Biogenesis and Down-Regulates Cytotoxic CD8 T-Cell Function in Autoimmune Cholangitis. Hepatology. 2021 Aug;74(2):835-846. doi:10.1002/hep.31724. Epub 2021 Aug 10. PMID:33462854.

Zhou X, Motta F, Selmi C, Ridgway WM, Gershwin ME, Zhang W. Antibody glycosylation in autoimmune diseases. Autoimmun Rev. 2021 May;20(5):102804. doi:10.1016/j.autrev.2021.102804. Epub 2021 Mar 14. PMID:33727152.

Zhang J, Lian M, Li B, Gao L, Tanaka T, You Z, Wei Y, Chen Y, Li Y, Li Y, Huang B, Tang R, Wang Q, Miao Q, Peng Y, Fang J, Lian Z, Okazaki K, Xiao X, Zhang W, Ma X. Interleukin-35 Promotes Th9 Cell Differentiation in IgG4-Related Disorders: Experimental Data and Review of the Literature. Clin Rev Allergy Immunol. 2021 Feb;60(1):132-145. doi:10.1007/s12016-020-08803-8. PMID:32712804.