Hisham Hussan, M.D. for UC Davis Health

Hisham Hussan, M.D.

Associate Professor

To see if Hisham Hussan is accepting new patients, or for assistance finding a UC Davis doctor, please call 800-2-UCDAVIS (800-282-3284).





Internal Medicine

Locations and Contact

Philosophy of Care

Dr. Hussan is invested in helping patients reach a better quality of life by applying the most recent evidence-based medicine and the highest level of empathy in patient-centered value-based care.

Clinical Interests

As a general gastroenterologist, Dr. Hussan focuses on improving various gastrointestinal symptoms. Dr. Hussan's particular interests focus on colorectal cancer prevention in adults with or without a predisposition to inherited colorectal cancer. Another area of expertise for Dr. Hussan is improving the gastrointestinal health of adults with obesity or prior bariatric surgery.

Research/Academic Interests

Dr. Hussan main research investigates the interface of energy balance and nutrition, the colonic microbiome and metabolome and impact on colorectal cancer risk. Dr. Hussan's other research is focused on improving colorectal cancer screening using artificial intelligence.


Gastroenterology and Hepatology

Center/Program Affiliation

UC Davis Comprehensive Cancer Center

Medical School

M.D., Damascus University School of Medicine, 2006


Internal Medicine, St. Louis University School of Medicine, 2009


Internal Medicine, St. Louis University School of Medicine, 2011


Gastroenterology, St. Louis University School of Medicine, 2014

Kidney, Nutrition, Obesity and Diabetes - KNOD NIH Study Section (ad hoc member), 2021

The Dr. Michael Grever Clinical Research Award in Gastroenterology, 2021

Colorectal Cancer Prevention Award for the best scientific paper, American College of Gastroenterology, 2020

Obesity Award for the best scientific papers, The American College of Gastroenterology, 2016-2020,

Best Senior Resident Lecture Award. Saint Louis University School of Medicine, 2011

Dr. Hussan's full bibliography: https://www.ncbi.nlm.nih.gov/pubmed/?term=hisham+hussan

Thompson HJ, Lutsiv T, McGinley JN, Hussan H, Playdon MC. Dietary Oncopharmacognosy as a Crosswalk between Precision Oncology and Precision Nutrition. Nutrients. 2023 May 8;15(9):2219. doi: 10.3390/nu15092219. PMID: 37432381; PMCID: PMC10180692.

Benson AB, Venook AP, Al-Hawary MM, Azad N, Chen YJ, Ciombor KK, Cohen S, Cooper HS, Deming D, Garrido-Laguna I, Grem JL, Hecht JR, Hoffe S, Hubbard J, Hunt S, Hussan H, Jeck W, Johung KL, Joseph N, Kirilcuk N, Krishnamurthi S, Maratt J, Messersmith WA, Meyerhardt J, Miller ED, Mulcahy MF, Nurkin S, Overman MJ, Parikh A, Patel H, Pedersen K, Saltz L, Schneider C, Shibata D, Skibber JM, Sofocleous CT, Stotsky-Himelfarb E, Tavakkoli A, Willett CG, Williams G, Algieri F, Gurski L, Stehman K. Anal Carcinoma, Version 2.2023, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 2023 Jun;21(6):653-677. doi: 10.6004/jnccn.2023.0030. PMID: 37308125.

Hussan H, Ali MR, Hussain SK, Lyo V, McLaughlin E, Chiang C, Thompson HJ. The impact of surgical weight loss procedures on the risk of metachronous colorectal neoplasia: the differential effect of surgery type, sex, and anatomic location. J Natl Cancer Inst Monogr. 2023 May 4;2023(61):77-83. doi: 10.1093/jncimonographs/lgac029. PMID: 37139983; PMCID: PMC10157775.

Hussan H, Akinyeye S, Mihaylova M, McLaughlin E, Chiang C, Clinton SK, Lieberman D. Colorectal Cancer Risk Is Impacted by Sex and Type of Surgery After Bariatric Surgery. Obes Surg. 2022 Jun 22. doi: 10.1007/s11695-022-06155-0. Epub ahead of print. PMID: 35731459.

Hussan H, Abu Dayyeh B, Chen J, et al. Adjustable intragastric balloon leads to significant improvement in obesity-related lipidome and fecal microbiome profiles: a proof of concept study, Clinical and Translational Gastroenterology: June 7, 2022 - Volume - Issue - 10.14309/ctg.0000000000000508 doi: 10.14309/ctg.0000000000000508 

Patel A, Krishna SG, Patel K, Gray DM 2nd, Mumtaz K, Stanich PP, Hinton A, Hussan H. Rising Rates of Severe Obesity in Adults Younger Than 50 Corre-spond to Rise in Hospitalizations for Non-malignant Gastrointestinal Disease. Dig Dis Sci. 2022 Jun 15. doi: 10.1007/s10620-022-07589-3. Epub ahead of print. PMID: 35704253.

Hussan H, Zhao J, Badu-Tawiah AK, Stanich P, Tabung F, Gray D, Ma Q, Kala-dy M, Clinton SK. Utility of machine learning in developing a predictive model for early-age-onset colorectal neoplasia using electronic health records. PLoS One. 2022 Mar 10;17(3):e0265209. doi: 10.1371/journal.pone.0265209. PMID: 35271664.

Al-Taee AM, Cubillan MP, Hinton A, Sobotka LA, Befeler AS, Hachem CY, Hussan H. Accuracy of virtual chromoendoscopy in differentiating gastric antral vascular ectasia from portal hypertensive gastropathy: A proof of concept study. World J Hepatol. 2021 Dec 27;13(12):2168-2178. doi: 10.4254/wjh.v13.i12.2168. PMID: 35070017; PMCID: PMC8727217.

Abu Dayyeh BK, Maselli DB, Rapaka B, Lavin T, Noar M, Hussan H, Chapman CG, Popov V, Jirapinyo P, Acosta A, Vargas EJ, Storm AC, Bazerbachi F, Ryou M, French M, Noria S, Molina D, Thompson CC. Adjustable intragastric balloon for treatment of obesity: a multicentre, open-label, randomised clinical trial. Lancet. 2021 Nov 27;398(10315):1965-1973. doi: 10.1016/S0140-6736(21)02394-1. Epub 2021 Nov 15. Erratum in: Lancet. 2021 Nov 27;398(10315):1964. PMID: 34793746.

Patel K, Porter K, Krishna SG, Needleman BJ, Brethauer SA, Conwell DL, Hussan H. The Impact of Bariatric Surgery on Diverticulitis Outcomes and Risk of Recurrent Hospitalizations in Adults with Clinically Severe Obesity. Obes Surg. 2022 Feb;32(2):365-373. doi: 10.1007/s11695-021-05764-5. Epub 2021 Nov 3. PMID: 34731417.

Shi N, Aroke D, Jin Q, Lee DH, Hussan H, Zhang X, Manson JE, LeBlanc ES, Barac A, Arcan C, Clinton SK, Giovannucci EL, Tabung FK. Proinflammatory and Hyperinsulinemic Dietary Patterns Are Associated With Specific Profiles of Bi-omarkers Predictive of Chronic Inflammation, Glucose-Insulin Dysregulation, and Dyslipidemia in Postmenopausal Women. Front Nutr. 2021 Sep 20;8:690428. doi: 10.3389/fnut.2021.690428. PMID: 34616762; PMCID: PMC8488136.