Angela Gomez-Simmonds, M.D., M.S.
Assistant Clinical Professor, Division of Infectious Diseases, Department of Internal Medicine
To see if Angela Gomez-Simmonds is accepting new patients, or for assistance finding a UC Davis doctor, please call 800-2-UCDAVIS (800-282-3284).
Locations and Contact
Philosophy of Care
I strive to provide thoughtful and compassionate care to all of my patients that integrates the best available research evidence and clinical expertise and tailors it to meet their individual needs, priorities, and preferences.
Clinical Interests
Dr. Gomez-Simmonds is a specialist in infectious diseases with experience treating a broad range of complex infections in hospitalized patients. She has a particular clinical interest in detecting and treating infections caused by multidrug-resistant bacteria, as well as understanding how they spread and develop resistance to antibiotics.
Research/Academic Interests
Dr. Gomez-Simmonds’ research is focused on understanding the epidemiology of multidrug-resistant Gram-negative bacteria causing hospital-associated infections. Her research entails uses whole genome sequencing to investigate the mechanisms of antibiotic resistance, evolution, and transmission of these high-risk pathogens. She has a particular interest in characterizing plasmids and other mobile genetic elements associated with the spread of antibiotic resistance genes. Additional research interests include identifying clinical risk factors and optimal detection and treatment strategies for multidrug-resistant infections.
Division
Infectious Diseases
Undergraduate School
B.S., Biology, University of Pennsylvania, Philadelphia PA 2003
Medical School
M.D., Medicine, New Jersey Medical School, Newark NJ 2008
Other School
M.S., Biostatistics, Patient-Oriented Research, Columbia University, Mailman School of Public Health, New York NY 2015
Internship
Internal Medicine, Columbia University, College of Physicians and Surgeons, New York NY 2008-2009
Residency
Internal Medicine, Columbia University, College of Physicians and Surgeons, New York NY 2009-2011
Fellowship
Infectious Diseases, Columbia University, College of Physicians and Surgeons, New York NY 2012-2015
Young Physician-Scientist Award, American Society of Clinical Investigation, 2021,
Gomez-Simmonds A, Annavajhala MK, Tang N, Rozenberg FD, Ahmad M, Park H, Lopatkin AJ, Uhlemann AC. Population structure of blaKPC-harbouring IncN plasmids at a New York City medical centre and evidence for multi-species horizontal transmission. Journal of Antimicrobial Chemotherapy 2022;77:1873-1882.
Gomez-Simmonds A, Annavajhala MK, Nunez MP, Macesic N, Park H, Uhlemann AC. Intestinal dysbiosis and risk of post-transplant Clostridioides difficile infection in a longitudinal cohort of liver transplant recipients. mSphere 2022;7:e0036122.
Gomez-Simmonds A, Annavajhala MK, McConville TH, Dietz DE, Shoucri SM, Laracy JC, Rozenberg FD, Nelson B, Greendyke WG, Furuya EY, Whittier S, Uhlemann AC. Carbapenemase-producing Enterobacterales causing secondary infections during the COVID-19 crisis at a New York City hospital. Journal of Antimicrobial Chemotherapy 2021;76:380-384.
Annavajhala MK, Gomez-Simmonds A, Macesic N, Sullivan SB, Kress A, Khan SD, Giddins MJ, Stump S, Kim GI, Narain R, Verna EC, Uhlemann AC. Colonizing multidrug-resistant bacteria and the longitudinal evolution of the intestinal microbiome after liver transplantation. Nature Communications 2019;10:4715.
Gomez-Simmonds A, Stump S, Giddins MJ, Annavajhala MK, Uhlemann AC. Clonal background, resistance gene profile, and porin gene mutations modulate in vitro susceptibility to imipenem-relebactam in diverse Enterobacteriaceae. Antimicrobial Agents and Chemotherapy 2018;62:e00573-18.
Gomez-Simmonds A#, Annavajhala MK#, Wang Z#, Macesic N, Hu Y, Giddins MJ, O’Malley A, Toussaint NC, Whittier S, Torres V, Uhlemann AC. Carbapenem-resistant Enterobacter cloacae complex demonstrates multifactorial genomic adaptation to nosocomial environment. mBio 2018;29:e00542-18. (#contributed equally)
Macesic N, Gomez-Simmonds A, Sullivan SB, Giddins MJ, Ferguson SA, Korakavi G, Leeds D, Park S, Shim K, Sowash MG, Hoffbauer M, Finkel R, Hu Y, West J, Toussaint NC, Greendyke WG, Miko BA, Pereira MR, Whittier S, Verna EC, Uhlemann AC. Genomic surveillance reveals diversity of multi-drug resistant organism colonization and infection: a prospective cohort study in liver transplant recipients. Clinical Infectious Diseases 2018;67:905-912.
Gomez-Simmonds A, Hu Y, Sullivan SB, Wang Z, Whittier S, Uhlemann AC. Evidence from a New York City hospital of rising incidence of genetically diverse carbapenem-resistant Enterobacter cloacae and dominance of ST171, 2007 – 2014. Journal of Antimicrobial Chemotherapy 2016;71:2351-3.
Gomez-Simmonds A, Nelson BC, Eiras DP, Loo AS, Jenkins SG, Whittier S, Calfee DP, Satlin MJ, Kubin CJ, Furuya EY. Combination regimens for the treatment of carbapenem-resistant Klebsiella pneumoniae bloodstream infections. Antimicrobial Agents and Chemotherapy 2016;60:3601-7.
Gomez-Simmonds A, Greenman M, Sowash M, Sullivan SB, Tanner J, Uhlemann AC. Population structure of Klebsiella pneumoniae causing bloodstream infections at a New York City tertiary care hospital: diversification of multidrug-resistant isolates. Journal of Clinical Microbiology 2015;53:2060-7.