Research
Training Program in Basic and Translational Cardiovascular Science
Objectives
The main goals of this training program include connecting basic and clinical science trainees, integrating basic and translational research, and providing high caliber research training. Quality training is made possible with a combination of outstanding and energetic faculty leadership and an exceptional pool of talented trainees (graduate students, postdoctoral fellows and clinical research fellows), who share a commitment to solving major issues in cardiovascular- and vascular-related diseases.
The overall objectives of the proposed training program are as follows:
- Select the most qualified predoctoral/graduate students interested in cardiovascular research from the participating graduate groups: Molecular and Cellular Integrative Physiology (MCIP), Biochemistry, Molecular, Cellular and Developmental Biology (GBCB), Pharmacology and Toxicology (PTX), Biomedical Engineering (BME) and other Graduate Programs
- Select the most qualified clinical fellows and residents, who demonstrate a commitment to basic and/or translational research and to becoming physician scientists
- Select the most qualified postdoctoral fellows, who demonstrate a commitment to cardiovascular research, from the faculty trainers’ laboratories.
The training program offers a multidisciplinary and extensive set of graduate level courses that provide comprehensive coverage in cardiovascular topics and in-depth discussion in biostatistics, bioinformatics, bioethics and courses on responsible conduct in research. Participation in journal clubs, weekly cardiovascular research group meetings, summer courses, annual retreats and the basic and translational research learning groups will further enhance the research experiences of the trainees. The overall aims are to facilitate the professional development through required courses, as well as, active participation in oral and written scientific presentation, and career survival skills.
In summary, the training program emphasizes a special focus in membrane proteins and cardiovascular and vascular-related diseases, while remained integrated into the wider area of graduate training at UC Davis. The program shares several resources provided by the University. The training program consists of distinct character in providing basic and translational research training for graduate students and postdoctoral/clinical fellows in the form of (1) Basic courses important for a strong background relevant to cardiovascular diseases; (2) advanced courses; (3) basic and translational learning groups, journal clubs, cardiovascular research group weekly meetings, and retreats; (4) summer school; (5) courses in bioinformatics, imaging, proteomics and metabolomics; (6) bioethics course; (7) a “Techniques for Scientific Presentation” course; (8) a “Grant & Manuscript Writing” course and; (9) career development.
A complete application consists of the following:
- Application Cover Sheet
- SciENcv (NIH format) or CV for applicant
- SciENcv and NIH other support page for Mentor
- Faculty/sponsor nomination letter
- Research Plan (2-3 page limit)
- Career goals (1 page limit)
- Two letters of recommendation
Please send applications to the T32 Program Officer listed below. The deadline for applications is March 20 with a start date of July 1.
Lisa Franzi
T32 Program Officer
T32-cardio@health.ucdavis.edu
As a trainee in this program, it will be your opportunity and responsibility to ensure that this support will go towards realizing these goals, in the form of joint publications with cross-disciplinary laboratories, with the grant number cited.
Our training program is a full-time (one year) curriculum starting on July 1 through June 30 which includes a ten-week Summer School, Directed Reading of the Literature in Fall, Winter and Spring quarter, Meet the Faculty, Translational Learning Group Meetings, Distinguished Speakers Seminar Series. We expect full participation of our trainees in all program activities.
Martin Cadeiras, M.D.
T32 Program Director and Mentor
Department of Internal Medicine
Division of Cardiovascular Medicine
David Liem, M.D., Ph.D.
T32 Program Co-Director
Department of Internal Medicine
Division of Cardiovascular Medicine
- Ezra Amsterdam, M.D.
Clinical and outcome research in coronary artery disease - Ramsey Badawi, Ph.D.
Development and application of nuclear medicine and molecular imaging - Donald Bers, Ph.D.
Regulation of cardiac Ca signaling and excitation-contraction coupling - Julie Bossuyt, Ph.D.
Regulation and function of Protein kinase D and calmodulin dependent protein kinase II in the heart - Martin Cadeiras, M.D.
Next Generation Phenomics of Heart Failure patients - Ye Chen-Izu, Ph.D.
Cardiac electrophysiology, Ca signaling, mechanotransduction, arrhythmia, heart failure - Simon Cherry, Ph.D.
Development of novel multimodal imaging - Colleen Clancy, Ph.D.
Computer modeling of drug interactions and cardiac arrhythmias - Eamonn Dickson, Ph.D.
Phosphoinositide regulation of ion channel function - Rose Dixon, Ph.D.
Role of L-type calcium channel interactions in cardiac EC coupling - Imo Ebong, M.D.
Epidemiology and gender disparities in heart failure - Vladimir Filkov, Ph.D.
Data science and ML in precision medicine - Steven George, Ph.D.
Tissue engineering - Aldrin Gomes, Ph.D.
Proteostasisdavisvarsity - Eleonora Grandi, Ph.D.
Cardiac arrhythmia mechanisms, computational biolog - Johannes W. Hell, Ph.D.
Postsynaptic signaling mechanisms - Leighton Izu, Ph.D.
Cardiac arrhythmia, heart failure, Ca signaling, mechanics, mathematical modeling - J. Kent Leach, Ph.D.
Biomaterials, tissue engineering, cell and drug delivery - Deborah K. Lieu, Ph.D.
Pluripotent stem cell-derived cardiomyocytes - Javier E. López, M.D.
Translational and clinical research in cardiac hypertrophy and failure - Angelique Louie, M.D.
Multimodal imaging, PET imaging - Laura Marcu, Ph.D.
Optical spectroscopy and imaging techniques for medical diagnostics, multimodal tissue diagnostic platforms including high-frequency ultrasound technologies - Stefano Morotti, Ph.D.
Mathematical models of cardiac and vascular myocyte electrophysiology, ion transport, and signaling - Manuel Navedo, Ph.D.
Calcium signaling and ion channels in the vasculature - Madeline Nieves-Cintron, Ph.D.
Vascular smooth muscle ion channels and control of intracellular calcium - Jan Nolta, Ph.D.
Regenerative Medicine - Kent Pinkerton, Ph.D.
Environmental air pollution and impact on cardiovascular system - Crystal Ripplinger, Ph.D.
Functional roles of cardiac nerve innervation in cardiac arrhythmias - Jason Rogers, M.D.
Clinical and outcome research in interventional cardiology - Luis Santana, Ph.D.
Ca signaling in cardiac and vascular smooth muscle - Daisuke Sato, Ph.D.
Mathematical analysis and multiscale modelling of cardiac ion channels - David J. Segal, Ph.D.
Genetic and Epigenetic Editing for Neurologic Disease - Eduardo A. Silva, Ph.D.
Biomaterials, polymers for drug delivery, gene delivery, tissue engineering - Scott Simon, Ph.D.
Inflammation with focus on leukocyte-endothelial interactions in atherosclerosis - Thomas Smith, M.D.
Multimodality Cardiovascular Imaging - Uma Srivatsa, M.D.
Cardiac Electrophysiology - Joshua Stern, D.V.M., Ph.D.
Cardiovascular disease of companion animals - Igor Vorobyov, Ph.D.
Computer modeling and simulation of drug interactions with membrane - Aijun Wang, Ph.D.
Stem cells, biomaterials, tissue regeneration, vascular disease, birth defects - Heike Wulff, Ph.D.
K+channel pharmacology - Vladimir Yarov-Yarovoy, Ph.D.
Ion channels, Computational Biology