Training Program in Basic and Translational Cardiovascular Science
Objectives
The main goals of this training program include: connecting basic and clinical science trainees, integrating basic and translational research, and providing high caliber research training. Quality training is made possible with a combination of outstanding and energetic faculty leadership and an exceptional pool of talented trainees (graduate students, postdoctoral fellows and clinical research fellows), who share a commitment to solving major issues in cardiovascular- and vascular-related diseases.
The overall objectives of the proposed training program are as follows:
- Select the most qualified predoctoral/graduate students interested in cardiovascular research from the participating graduate groups: Molecular and Cellular Integrative Physiology (MCIP), Biochemistry, Molecular, Cellular and Developmental Biology (GBCB), Pharmacology and Toxicology (PTX), Biomedical Engineering (BME), Biophysics (BPH), and other Graduate Programs
- Select the most qualified clinical fellows and residents, who demonstrate a commitment to basic and/or translational research and to becoming physician scientists
- Select the most qualified postdoctoral fellows, who demonstrate a commitment to cardiovascular research, from the faculty trainers’ laboratories.
The training program offers a multidisciplinary and extensive set of graduate level courses that provide comprehensive coverage in cardiovascular topics and in-depth discussion in biostatistics, bioinformatics, bioethics and courses on responsible conduct in research. Participation in journal clubs, weekly cardiovascular research group meetings, summer courses, annual retreats and the basic and translational research learning groups will further enhance the research experiences of the trainees. The overall aims are to facilitate the professional development through required courses, as well as, active participation in oral and written scientific presentation, and career survival skills.
In summary, the training program emphasizes a special focus in membrane proteins and cardiovascular and vascular-related diseases, while remained integrated into the wider area of graduate training at UC Davis. The program shares several resources provided by the University. The training program consists of distinct character in providing basic and translational research training for graduate students and postdoctoral/clinical fellows in the form of (1) Basic courses important for a strong background relevant to cardiovascular diseases; (2) advanced courses; (3) basic and translational learning groups, journal clubs, cardiovascular research group weekly meetings, and retreats; (4) summer school; (5) courses in bioinformatics, imaging, proteomics and metabolomics; (6) bioethics course; (7) a “Techniques for Scientific Presentation” course; (8) a “Grant & Manuscript Writing” course and; (9) career development.
Application Guidelines
Conditions of Award
As a trainee in this program, it will be your opportunity and responsibility to insure that this support will go towards realizing these goals, in the form of joint publications with cross-disciplinary laboratories, with the grant number cited.
Our training program is a full-time (one year) curriculum starting on July 1 through June 30 which include a ten-week Summer School, Directed Reading of the Literature in Fall, Winter and Spring quarter, Meet the Faculty, Translational Learning Group Meetings, Distinguished Speakers Seminar Series. We expect full participation of our trainees in all program activities.
Eligibility
- All nominees must be citizens or permanent visa residents of the United States.
- If funded, the students and fellows must present his/her research at the Annual Training Program Retreat and participate in the Training Program Activities. All publications must cite the training grant (T32 HL086350).
- It is essential that the nominees be students and postdoctoral fellows who have the best potential of becoming first-rate independent Cardiovascular Research scientists. Scholastic achievement, innovation and interdisciplinary research weigh heavily in the selection. Collaborations between laboratories and crossing traditional boundaries are also important in the selection process. Research proposal and progress are highly valued as well as excellent GRE scores and graduate level GPA.
How to Apply
A complete application consists of the following:
- Biographical sketch or CV
- Concise plan (1-3 pages) of proposed research or statement of research interests and a description of career goals
- Copy of graduate and undergraduate academic records
- Three letters of recommendation
- Nomination letter from faculty sponsor and sponsor’s other funding support
Applications should be sent to the individual listed below. The deadline for applications is May 15 with a start date of July 1.
Dr. N. Chiamvimonvat
Molecular and Cellular Cardiology
One Shields Avenue, Davis, CA, 95616
T32 Program Coordinator
Chandra Reid
creid@ucdavis.edu
Molecular and Cellular Cardiology
One Shields Avenue, Davis, CA, 95616
Curricular Activities
- Summer Course
- Seminar Series
During the seminar series, all trainees and faculty trainers will have the opportunity to present their research-in-progress to the group. We will also invite speakers from the campus whose research is of interest to the group. In addition, we will invite distinguished speakers who are experts in the field of our research focus group on a bi-monthly basis (a total of 6 speakers per year).
- Journal Clubs
- Evening Dinners
- Learning Groups
- K30 Workshops
- Graduate Studies Workshops
Leadership
Program Director
Nipavan Chiamvimonvat, M.D.
Program Director and Mentor
Department of Internal Medicine
Division of Cardiovascular Medicine
Mentors/Trainers
Ezra Amsterdam, M.D., Clinical and outcome research in coronary artery disease
Ramsey Badawi, Ph.D., Development and application of nuclear medicine and molecular imaging
Donald Bers, Ph.D., Regulation of cardiac Ca signaling and excitation-contraction coupling
Julie Bossuyt, Ph.D., Regulation and function of Protein kinase D and calmodulin dependent protein kinase II in the heart
Martin Cadeiras, M.D., Next Generation Phenomics of Heart Failure patients
Ye Chen-Izu, Ph.D., Cardiac electrophysiology, Ca signaling, mechanotransduction, arrythmia, heart failure
Simon Cherry, Ph.D., Development of novel multimodal imaging
Nipavan Chiamvimonvat, M.D., Cardiac ion channel regulation and cardiac arrhythmias
Colleen Clancy, Ph.D., Computer modeling of drug interactions and cardiac arrhythmias
Eamonn Dickson, Ph.D., Phosphoinositide regulation of ion channel function
Rose Dixon, Ph.D., Role of L-type calcium channel interactions in cardiac EC coupling
Imo Ebong, M.D., Epidemiology and gender disparities in heart failure
Vladimir Filkov, Ph.D., Data science and ML in precision medicine
Steven George, Ph.D., Tissue engineering
Aldrin Gomes, Ph.D., Proteostasisdavisvarsity
Eleonora Grandi, Ph.D., Cardiac arrhythmia mechanisms, computational biolog
Bruce Hammock, Ph.D., Inhibitors of alpha/beta hydrolase enzymes, metabolomics
Johannes W. Hell, Ph.D., Postsynaptic signaling mechanisms
Leighton Izu, Ph.D., Cardiac arrhythmia, heart failure, Ca signaling, mechanics, mathematical modeling
Anne A. Knowlton, M.D., Roles of heat shock proteins in cardiovascular diseases
J. Kent Leach, Ph.D., Biomaterials, tissue engineering, cell and drug delivery
Deborah K. Lieu, Ph.D., Pluripotent stem cell-derived cardiomyocytes
Javier E. López, M.D., Translational and clinical research in cardiac hypertrophy and failure
Angelique Louie, M.D., Multimodal imaging, PET imaging
Laura Marcu, Ph.D., Optical spectroscopy and imaging techniques for medical diagnostics, multimodal tissue diagnostic platforms including high-frequency ultrasound technologies
Stefano Morotti, Ph.D., Mathematical models of cardiac and vascular myocyte electrophysiology, ion transport, and signaling
Manuel Navedo, Ph.D., Calcium signaling and ion channels in the vasculature
Madeline Nieves-Cintron, Ph.D., Vascular smooth muscle ion channels and control of intracellular calcium
Jan Nolta, Ph.D., Regenerative Medicine
Kent Pinkerton, Ph.D., Environmental air pollution and impact on cardiovascular system
Crystal Ripplinger, Ph.D., Functional roles of cardiac nerve innervation in cardiac arrhythmias
Jason Rogers, M.D., Clinical and outcome research in interventional cardiology
Luis Santana, Ph.D., Ca signaling in cardiac and vascular smooth muscle
Daisuke Sato, Ph.D., Mathematical analysis and multiscale modelling of cardiac ion channels
David J. Segal, Ph.D., Genetic and Epigenetic Editing for Neurologic Disease
Eduardo A. Silva, Ph.D., Biomaterials, polymers for drug delivery, gene delivery, tissue engineering
Scott Simon, Ph.D., Inflammation with focus on leukocyte-endothelial interactions in atherosclerosis
Thomas Smith, M.D., Multimodality Cardiovascular Imaging
Uma Srivatsa, M.D., Cardiac Electrophysiology
Joshua Stern, D.V.M., Ph.D., Cardiovascular disease of companion animals
Igor Vorobyov, Ph.D., Computer modeling and simulation of drug interactions with membrane
Heike Wulff, Ph.D., K+channel pharmacology
Yang Xiang, Ph.D., Adrenergic and insulin receptor signaling networks in the central and peripheral systems
Vladimir Yarov-Yarovoy, Ph.D., Ion channels, Computational Biology