George Thompson, M.D.
Professor of Medicine
To see if George Thompson is accepting new patients, or for assistance finding a UC Davis doctor, please call 800-2-UCDAVIS (800-282-3284).
Locations and Contact
Patient Support Services Building
Patient Support Services Building
4150 V Street
Sacramento, CA 95817
Clinical Interests
Dr. George Thompson is a Professor of Medicine at the University of California, Davis, School of Medicine (Sacramento, CA) with a joint appointment in the Departments of Medical Microbiology and Immunology, and Internal Medicine, Division of Infectious Diseases. Dr. Thompson specializes in the care of patients with invasive fungal infections and his research interests are in fungal epidemiology, pathophysiology, diagnostics, treatments, and outcomes.
Research/Academic Interests
Dr. Thompson focuses on the fungal diseases caused by Aspergillus, Candida, and Coccidioides spp. These fungi are of both regional and global importance. Aspergillus infections continue to emerge in new patient populations (eg COVID19), Candida spp are the 4th leading cause of bloodstream infections across the world and carry substantial morbidity and mortality, and coccidioidomycosis affects over 450,000 people per year within the Southwestern United States. Our studies focus on the evaluation of new antifungal agents, the pathophysiologic mechanisms of antifungal therapy, including both the development of resistance and the biologic underpinnings of adverse drug reactions.
He served as the co-chair of the National Academy of Sciences Symposium on Coccidioidomycosis in the fall of 2022, and as an advisor to the World Health Organization (WHO) for fungal priority pathogens. He has additionally served on multiple international guidelines which are highly utilized by clinicians globally. He currently is the chair of the Mycoses Study Group Education Committee – and is responsible for the development of fungal educational content to practitioners globally and the design of pivotal clinical trials. He has served on both the CDC and the National Institute of Allergy and Infectious Diseases Special Emphasis Panels as a grant reviewer and on the FDA Antifungal and Coccidioidomycosis Advisory committees. He has also been a congressional consultant for the Valley Fever Task Force, and the Congressional Pasteur and Forward Acts focused on antifungal and antibacterial resistance.
Division
Infectious Diseases
Undergraduate School
B.S., University of Missouri, Columbia MO 1999
Medical School
M.D., University of Missouri, Columbia MO 2003
Internship
Internal Medicine, University of Texas, San Antonio TX 2003-2004
Residency
Internal Medicine, University of Texas, San Antonio TX 2004-2006
Residency
Chief Resident, University of Texas, San Antonio TX 2006-2007
Fellowship
Infectious Diseases, University of Texas, San Antonio TX 2007-2009
Internal Medicine Outstanding Clinician Award, UC Davis, 2021
Sacramento Top Doctors, Infectious Diseases, 2018, 2019, 2020, 2021
Top 10 Papers that will change your clinical practice, IDWeek, Washington DC, 2019
Internal Medicine Faculty Research Award, UC Davis, 2017
Outstanding Young Physician Award, University of Missouri School of Medicine, 2014
Bays DJ, Thompson GR, Reef S, Snyder L, Freifeld AJ, Huppert M, Salkin D, Wilson MD, Galgiani JN. Natural History of Disseminated Coccidioidomycosis: Examination of the Veterans Affairs-Armed Forces Database. Clin Infect Dis. 2021 Dec 6;73(11):e3814-e3819. doi:10.1093/cid/ciaa1154. PMID:32778863.
Thompson GR, Soriano A, Skoutelis A, Vazquez JA, Honore PM, Horcajada JP, Spapen H, Bassetti M, Ostrosky-Zeichner L, Das AF, Viani RM, Sandison T, Pappas PG. Rezafungin Versus Caspofungin in a Phase 2, Randomized, Double-blind Study for the Treatment of Candidemia and Invasive Candidiasis: The STRIVE Trial. Clin Infect Dis. 2021 Dec 6;73(11):e3647-e3655. doi:10.1093/cid/ciaa1380. Erratum in: Clin Infect Dis. 2021 Aug 2;73(3):561-562. PMID:32955088.
Thompson GR 3rd, Young JH. Aspergillus Infections. N Engl J Med. 2021 Oct 14;385(16):1496-1509. doi:10.1056/NEJMra2027424. PMID:34644473.
Thompson GR 3rd, Le T, Chindamporn A, et al. Global guideline for the diagnosis and management of the endemic mycoses: an initiative of the European Confederation of Medical Mycology in cooperation with the International Society for Human and Animal Mycology. Lancet Infect Dis. 2021 Aug 5. doi:10.1016/S1473-3099(21)00191-2. PMID:34364529. Correction: Lancet Infect Dis. 2021 Nov 1;21(11):E341. doi.org/10.1016/S1473-3099(21)00588-0.
Nguyen MH, Davis MR, Wittenberg R, Mchardy I, Baddley JW, Young BY, Odermatt A, Thompson GR. Posaconazole Serum Drug Levels Associated With Pseudohyperaldosteronism. Clin Infect Dis. 2020 Jun 10;70(12):2593-2598. doi:10.1093/cid/ciz741. PMID:31403165.
Thompson GR 3rd, Beck KR, Patt M, Kratschmar DV, Odermatt A. Posaconazole-Induced Hypertension Due to Inhibition of 11β-Hydroxylase and 11β-Hydroxysteroid Dehydrogenase 2. J Endocr Soc. 2019 Jun 6;3(7):1361-1366. doi:10.1210/js.2019-00189. PMID:31286100.
Stockamp NW, Thompson GR 3rd. Coccidioidomycosis. Infect Dis Clin North Am. 2016 Mar;30(1):229-46. doi:10.1016/j.idc.2015.10.008. Epub 2015 Dec 29. PMID:26739609.