clinician with paticipant talkingThe primary objective of the Clinical Translational (CT) Core is to support IDDRC projects by optimizing recruitment of a diverse range of individuals with neurodevelopmental disorders, including autism spectrum disorder (ASD), fragile X syndrome (FXS), Chromosome 22q11.2 deletion syndrome (22qDS), Down syndrome (DS), and attention deficit/hyperactivity disorder (ADHD), and providing diagnostic assessment services, neurobehavioral characterization, and collection of biological specimens. Researchers in the field often encounter challenges in recruiting sufficient numbers of well-characterized individuals with neurodevelopmental disorders, as well as meaningful comparison groups, including typically developing (TD) individuals. Increasingly, researchers also require tools for fully characterizing their participants in nuanced and complex ways along multiple dimensions to illuminate underlying neuropathology and causal mechanisms and suggest ways to adapt or develop treatments. The CT Core is designed to address these challenges.

Services Offered

  • Recruitment of a diverse range of participants. The CT Core participates in community events and outreach activities to engage new participants to research. It maintains a growing participant registry that includes multiple ethnicities, races, and economic backgrounds with both atypical and typical populations across a wide age span.
  • Behavioral and diagnostic characterization of human participants. The CT Core provides access to experienced clinicians who can conduct specialized evaluations, advise studies in best practices for assessment, instrument selection and participant engagement/compliance, provide training in administration of standardized measures, establish initial reliability, and monitor administration fidelity. Select services are offered in Spanish.
  • “Deep phenotyping” and genomics expertise. The CT Core offers tools and training at several service levels to enhance phenotypic characterization of participants, making available recent innovations in deep phenotyping (e.g., eye tracking, EEG, ERP) and genomics to IDDRC investigators.
  • Integration of technology into research. The CT Core provides on-site high-level research IT support and access to a full array of technologies, including telehealth, and other expertise at UC Davis Health, including the Center for Health Technology.
  • Collection and storage of biospecimens from human participants. The CT Core provides phlebotomy services and access and incentives to use a core-managed freezer library for biospecimen storage as well as by links to the MIND IDDRC Biological and Molecular Analysis Core and the MIND Institute Genomic Medicine Program. This promotes sharing across IDDRC projects.

Request services

Submit a request for IDDRC - Clinical Translation Core (CTC)

All CT Core services are requested through the online form above. The form collects details needed to fulfill the request (e.g., sample sizes, inclusion/exclusion criteria, targeted populations, timelines), and tracks utilization data that permits the Core to improve services and resources. Requests are reviewed weekly by the CT Core management team, who make decisions about resource allocation and respond within 48 hours to requests. First priority is IDDRC research projects.

If you are not an IDDRC approved project, please submit a request for approval.

IDDRC Research Project Application Form »

For questions, please contact Michele Ono, Project Manager myono@ucdavis.edu

Staff

Sally Ozonoff, Ph.D., » Core Director

Tony J. Simon, Ph.D., » Core Co-Director

Norman Brule, Core Manager

Brittani Phillips, Core Project Coordinator