John Paul Graff, B.S., D.O., M.A.S.

Assistant Professor, Division of Hematopathology and Informatics

John Paul Graff is not currently accepting new patients. For assistance finding a UC Davis doctor, please call 800-2-UCDAVIS (800-282-3284).





Locations and Contact

Pathology Building

4400 V St.
Sacramento, CA 95817

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Philosophy of Care

Dr. Graff applies his four board certifications in anatomic pathology, clinical pathology, hematopathology, and clinical informatics to accurately and efficiently diagnosis his patients allowing them access to the most optimal treatments available. As an osteopathic trained physician Dr. Graff considers the whole patient when reviewing their biopsies and laboratory data.

Clinical Interests

Dr. Graff's cliniical interests are malignant and non-malignant hematopathology with integration of flow cytometry and molecular testing to provide the most accurate diagnosis for my patient’s.

Research/Academic Interests

Dr. Graff is the associate director of clinical informatics at UC Davis Medical Center, actively training the next generation of physicians on how technology can improve the lives of patient’s and the physicians who work with them. Through his role in informatics and his expertise in machine learning, he as worked on a California wide initiative to classify the causes and types of Alzheimer’s dementia; working closely with his colleges at the other University of California campuses. Additionally, Dr. Graff has applied his expertise in Hematopathology in several publications related to the recent and ongoing COVID-10 pandemic and its impacts on the hematologic system. These publications help diagnosis and treat those critically ill with the virus as we discover more about its Pathophysiology.


Anatomic Pathology
Clinical Pathology

Center/Program Affiliation

UC Davis Comprehensive Cancer Center

Undergraduate School

B.S., Vanderbilt University School of Engineering, Nashville TN 2007

Medical School

D.O., Lincoln Memorial University DeBusk College of Osteopathic Medicine, Harrogate TN 2012


Anatomic Pathology & Clinical Pathology, UC Irvine Medical Center, Orange CA 2012-2016


Hematopathology, UC Davis Medical Center, Sacramento CA 2016-2017

CP Beaker Lead and Physician Trainer - Epic Beaker Implementation, 2017, 2018, 2019 2020, 2021

Fellow Teaching Award, UC Davis, 2017

Chief Resident, UC Irvine, 2015

Dwyre DM, Graff JP, Rashidi HH. Importance of bone marrow clot sections-Positive for metastatic tumor. Int J Lab Hematol. 2022 Aug;44(4):696-697. doi:10.1111/ijlh.13808. Epub 2022 Feb 16. PMID:35170236.

Mitra A, Datta Mitra A, Patel G, Dwyre DM, Graff JP. Leukoerythroblastosis in a Sickle Cell Patient With Pregnancy: An Interesting Peripheral Blood Smear Finding. J Hematol. 2022 Feb;11(1):15-20. doi:10.14740/jh921. Epub 2021 Dec 13. PMID:35356637.

Lee D, Omofoye OA, Karnati T, Graff JP, Shahlaie K. Intracranial myeloid sarcoma presentation in distant acute myeloid leukemia remission. J Clin Neurosci. 2021 Jul;89:158-160. doi:10.1016/j.jocn.2021.05.001. Epub 2021 May 12. PMID:34119261.

Mitra A, Dwyre DM, Schivo M, Thompson GR 3rd, Cohen SH, Ku N, Graff JP. Leukoerythroblastic reaction in a patient with COVID-19 infection. Am J Hematol. 2020 Aug;95(8):999-1000. doi:10.1002/ajh.25793. Epub 2020 Apr 6. PMID:32212392.

Jones AD, Graff JP, Darrow M, Borowsky A, Olson KA, Gandour-Edwards R, Datta Mitra A, Wei D, Gao G, Durbin-Johnson B, Rashidi HH. Impact of pre-analytical variables on deep learning accuracy in histopathology. Histopathology. 2019 Jul;75(1):39-53. doi:10.1111/his.13844. Epub 2019 May 16. PMID:30801768.

Kramer M, Antony R, Ozturk A, Lehn K, Graff JP, Chung JH. A Palpable Back Mass as First Presenting Sign of Acute Lymphoblastic Leukemia in a Pediatric Patient. J Pediatr Hematol Oncol. 2019 Jan;41(1):77-78. doi:10.1097/MPH.0000000000001214. PMID:29750743.

Monroy C, Panigrahi A, Kaur S, Graff J, Gwal K. Myeloid Sarcoma of the Pancreas in Pediatrics: a Diagnostic Conudrum, Poster Number 278. Am Soc Ped Hematol Oncol. 2019.

Mitra A, Datta-Mitra A, Graff JP. A 42-year old woman with a cervical mass: a rare diagnosis to decipher. ASCP Case Reports Manuscript. 2018. ID CHKS-2018-06-0026-H.R1.

Graff JP, Wu ML. The Nokia Lumia 1020 smartphone as a 41-megapixel photomicroscope. Histopathology. 2014 Jun;64(7):1044-5. doi:10.1111/his.12355. Epub 2014 Feb 14. PMID:24528478.