Denis Dwyre, M.D.

Denis M. Dwyre, M.D.


Pathology and Laboratory Medicine

Pathology - Clinical

Pathology - Hematopathology

Pathology - Apheresis


  • Director, Hematopathology
  • Professor


To see if Denis M. Dwyre is accepting new patients, or for assistance finding a UC Davis doctor, please call 800-2-UCDAVIS (800-282-3284).

Pathology Building

4400 V St.
Sacramento, CA 95817
Driving Directions

Primary Phone:

Additional Phone Numbers

Fax: 916-734-2560
Physician Referrals: 800-4-UCDAVIS (800-482-3284)

Clinical Interests

Dr. Dwyre has clinical responsibilities in hematopathology, including leukemia, lymphoma and flow cytometry, as well as apheresis (the withdrawal of blood from a donor's body, removal of one or more components, and transfusion of the remaining blood back into the donor), which includes pediatric apheresis and progenitor-cell collection.

He is involved in hematology-related clinical research involving leukemia, lymphoma and apheresis.

Research/Academic Interests

Dr. Dwyre's clinical research involves leukemia, lymphoma, and apheresis. Hematopathology — leukemia, lymphoma, flow cytometry. Apheresis — pediatric apheresis and progenitor cell collection.




M.D., University of Cincinnati College of Medicine, Cincinnati OH 1994

B.S., UC Davis, Davis CA 1985

Internship: Pathology, UC Davis Medical Center, Sacramento CA 1994-1995


Pathology/Internal Medicine, UC Davis Medical Center, Sacramento CA 1995-2000


Hematopathology, UC Davis Medical Center, Sacramento CA 2000-2001

Transfusion Medicine, University of Iowa, Iowa City IA 2003-2005

Board Certifications

American Board of Internal Medicine, 2000

American Board of Pathology, Blood Banking/Transfusion Medicine, 2005

American Board of Pathology, Clinical Pathology, 1998

American Board of Pathology, Hematology, 2001

Professional Memberships

American Association of Blood Banks

American College of Physicians (Internal Medicine)

American Society for Clinical Pathology

American Society of Hematology

College of American Pathologists

Society of Hematopathology

Honors and Awards

Excellence in Dermatology, University of Cincinnati, 1994

Excellence in Gross Anatomy, University of Cincinnati, 1991

Select Recent Publications

Gosselin RC, Carlin AC, Dwyre DM. Comparison of the BioRad Variant and Primus Ultra2 high-pressure liquid chromatography (HPLC) instruments for the detection of variant hemoglobins. Int J Lab Hematol. 2011 Apr;33(2):159-67. doi: 10.1111/j.1751-553X.2010.01260.x. Epub 2010 Sep 14.

Raife TJ, Dwyre DM, Stevens JW, Erger RA, Leo L, Wilson KM, Fern´┐Żndez JA, Wilder J, Kim HS, Griffin JH, Maeda N, Lentz SR. Human thrombomodulin knock-in mice reveal differential effects of human thrombomodulin on thrombosis and atherosclerosis. Arterioscler Thromb Vasc Biol. 2011 Nov;31(11):2509-17.

Smith ZJ, Chu K, Espenson AR, Rahimzadeh M, Gryshuk A, Molinaro M, Dwyre DM, Lane S, Matthews D, Wachsmann-Hogiu S. Cell-phone-based platform for biomedical device development and education applications. PLoS One. 2011 Mar 2;6(3):e17150.

Dwyre DM, Fernando LP, Holland PV. Hepatitis B, hepatitis C and HIV transfusion-transmitted infections in the 21st century. Vox Sang. 2011 Jan;100(1):92-8.

Trikha R, Yeung C, Modjtahedi S, Martin S, Dwyre DM, Telander DG. B-cell lymphoma line (Raji) viability and surface marker expression minimally affected by 20- and 25-gauge vitrectomy systems analyzed by flow cytometry. Retina. 2010 Oct;30(9):1505-10.

Bleile MJ, Rijhsinghani A, Dwyre DM, Raife TJ. Successful use of maternal blood in the management of severe hemolytic disease of the fetus and newborn due to anti-Kp(b). Transfus Apher Sci. 2010 Dec;43(3):281-3. Epub 2010 Oct 15.

Dwyre DM, Dursteler B, Nashelsky M, Friedman KD, Raife TJ. Value of ADAMTS13 activity and inhibitor in the postmortem diagnosis of thrombotic thrombocytopenic purpura. J Clin Apheresis 2009;24:106-110.

Dwyre DM, Holland PV. Transfusion associated graft-versus-host disease. Vox Sang 2008;95:85-93.