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Kuang-Yu Jen, M.D., Ph.D.
Director of Renal Pathology
Professor, Department of Pathology
To see if Kuang-Yu Jen is accepting new patients, or for assistance finding a UC Davis doctor, please call 800-2-UCDAVIS (800-282-3284).
Specialties
Pathology - Renal
Pathology - Transplant
Department
Locations and Contact
Patient Support Services Building
Patient Support Services Building - Pathology
4150 V St.
Sacramento, CA 95817
Additional Numbers
Physician Referrals
Clinical Interests
Dr. Jen is the Director of Renal Pathology and specializes in renal and transplant pathology. He is the primary contact for the Renal Pathology Outreach Service, which provides diagnostic assessment of native and transplant renal biopsies.
Research/Academic Interests
Dr. Jen's research focuses on using histopathologic data to predict clinical outcome, focusing on native kidney disease and renal transplants. Histopathologic data consists of morphologic findings obtained from traditional microscopic examination as well as developing and using state of the art deep learning-based image analysis on digital images.
Division
Anatomic Pathology
Undergraduate School
B.A., Northwestern University, Evanston IL 1998
Medical School
M.D., University of Pennsylvania School of Medicine, Philadelphia PA 2006
Other School
Ph.D., Cell & Molecular Biology, University of Pennsylvania, Philadelphia PA 2005
Residency
Anatomic Pathology, UC San Francisco Medical Center, San Francisco CA 2006-2009
Fellowship
Renal Pathology, UC San Francisco Medical Center, San Francisco CA 2010-2011
Fellowship
Surgical and Transplant Pathology, UC San Francisco Medical Center, San Francisco CA 2011-2012
Treasurer of the Renal Pathology Society, 2022-2024,
ASCP Leadership Institute Certificate Program, 2019,
Outstanding Poster, Kidney Research Symposium, UC Davis, 2017,
Physician Leadership and Executive Administration Development (LEAD) Program, 2023,
Fellow, Association of Pathology Chairs Pathology Leadership Fellows Program, 2024,
For complete list, please refer to: https://www.ncbi.nlm.nih.gov/myncbi/167Qgj2Ike-kg/bibliography/public/
Lutnick B, Manthey D, Becker JU, Zuckerman JE, Rodrigues L, Jen KY, Sarder P. A tool for federated training of segmentation models on whole slide images. J Pathol Inform. 2022 May 21;13:100101. doi:10.1016/j.jpi.2022.100101. PMID:35910077.
Lutnick B, Manthey D, Becker JU, Ginley B, Moos K, Zuckerman JE, Rodrigues L, Gallan AJ, Barisoni L, Alpers CE, Wang XX, Myakala K, Jones BA, Levi M, Kopp JB, Yoshida T, Zee J, Han SS, Jain S, Rosenberg AZ, Jen KY, Sarder P. A user-friendly tool for cloud-based whole slide image segmentation with examples from renal histopathology. Commun Med (Lond). 2022 Aug 19;2:105. doi:10.1038/s43856-022-00138-z. PMID:35996627.
Lucarelli N, Ginley B, Zee J, Mimar S, Paul AS, Jain S, Han SS, Rodrigues L, Ozrazgat-Baslanti T, Wong M, Nadkarni G, Clapp WL, Jen KY*, Sarder P*. Correlating deep learning-based automated reference kidney histomorphometry with patient demographics and creatinine. Kidney360. 2023 Dec 1;4(12):1726-1737. doi: 10.34067/KID.0000000000000299. PMID: 37966063. *co-corresponding author.
Hsu MF, Ito Y, Singh JP, Hsu SF, Wells A, Jen KY, Meng TC, Haj FG. Protein tyrosine phosphatase 1B is a regulator of alpha-actinin4 in the glomerular podocyte. Biochim Biophys Acta Mol Cell Res. 2024 Jan;1871(1):119590. doi: 10.1016/j.bbamcr.2023.119590. PMID: 37730132.
Yang T, Sucholutsky I, Jen KY, Schonlau M. exKidneyBERT: a language model for kidney transplant pathology reports and the crucial role of extended vocabularies. PeerJ Comput Sci. 2024 Feb 28;10:e1888. doi: 10.7717/peerj-cs.1888. PMID: 38435545.
Augulis R, Rasmusson A, Laurinaviciene A, Jen KY, Laurinavicius A. Computational pathology model to assess acute and chronic transformations of the tubulointerstitial compartment in renal allograft biopsies. Sci Rep. 2024 Mar 4;14(1):5345. doi: 10.1038/s41598-024-55936-3. PMID: 38438513.
Kondo A, McGrady M, Nallapothula D, Ali H, Trevino AE, Lam A, Preska R, D'Angio HB, Wu Z, Lopez LN, Badhesha HK, Vargas CR, Ramesh A, Wiegley N, Han SS, Dall'Era M, Jen KY, Mayer AT, Afkarian M. Spatial proteomics of human diabetic kidney disease, from health to class III. Diabetologia. 2024 Jul 22. doi: 10.1007/s00125-024-06210-8. PMID: 39037603.
Ng C, Penney A, Sharaflari R, Pathak A, Howard JH, Jen KY*. ANCA-negative pauci-immune glomerulonephritis associated with Bartonella endocarditis. Case Rep Nephrol. 2024 Sept 06;2024:4181660. doi: 10.1155/2024/4181660. *corresponding author.
Loza J, Alghannam K, Howard B, De Leon F, Fine J, Wang AX, Jen KY, Goussous N, Sageshima J, Perez RV, Than PA. Clinical and histologic risk factors for the development of early allograft dysfunction in donation after circulatory death kidney transplantation. Transplant Proc. 2025 Apr 29:S0041-1345(25)00215-5. doi: 10.1016/j.transproceed.2025.03.022. PMID: 40307129.
Ahmadi A, Yang H, Jen KY, Fan S, Palma I, Sageshima J, Goussous N, Roshanravan B, Perez RV. Packed red blood cell and whole blood perfusates during ex-vivo normothermic perfusion for assessment of high-risk donor kidneys. Kidney360. 2025 May 7. doi: 10.34067/KID.0000000815. PMID: 40333014.