Kuang-Yu Jen, M.D., Ph.D.
Specialties
Pathology - Renal
Pathology - Transplant
Department
Title
- Director of Renal Pathology
- Associate Professor
Reviews
Patient Support Services Building
4150 V St.
Sacramento, CA 95817
Driving Directions
Primary Phone:
Additional Phone Numbers
Physician Referrals: 800-4-UCDAVIS (800-482-3284)
Clinical Interests
Dr. Jen is the Director of Renal Pathology and specializes in renal and transplant pathology. He is the primary contact for the Renal Pathology Outreach Service, which provides diagnostic assessment of native and transplant renal biopsies.
Research/Academic Interests
Dr. Jen's research focuses on using histopathologic data to predict clinical outcome, focusing on native kidney disease and renal transplants. Histopathologic data consists of morphologic findings obtained from traditional microscopic examination as well as developing and using state of the art deep learning-based image analysis on digital images.
Division
Anatomic Pathology
Education
M.D., University of Pennsylvania School of Medicine, Philadelphia PA 2006
Ph.D., Cell & Molecular Biology, University of Pennsylvania, Philadelphia PA 2005
B.A., Northwestern University, Evanston IL 1998
Residency
Anatomic Pathology, UC San Francisco Medical Center, San Francisco CA 2006-2009
Fellowships
Renal Pathology, UC San Francisco Medical Center, San Francisco CA 2010-2011
Surgical and Transplant Pathology, UC San Francisco Medical Center, San Francisco CA 2011-2012
Board Certifications
American Board of Pathology, Anatomic Pathology,
Professional Memberships
American Society of Nephrology
College of American Pathologists
Renal Pathology Society
United States - Canadian Academy of Pathology
Honors and Awards
ASCP Leadership Institute Certificate Program, 2019
Outstanding Poster, Kidney Research Symposium, UC Davis, 2017
Excellence in Teaching Award, Haile T. Debas Academy of Medical Educators, UCSF, 2015
Chief Resident, Anatomic Pathology, UCSF, 2011
Resident Teaching Award, Department of Pathology, UCSF, 2011
Select Recent Publications
Govind D, Jen KY, Matsukuma K, Gao G, Olson KA, Gui D, Wilding GE, Border SP, Sarder P. Improving the accuracy of gastrointestinal neuroendocrine tumor grading with deep learning. Sci Rep. 2020 Jul 6;10(1):11064. doi:10.1038/s41598-020-67880-z.
Fananapazir G, Navarro SM, Zhou C, Jen KY, Loehfelm TW, Stewart SL, Troppmann C, Lamba R. Sonographically Diagnosed Urothelial Thickening in Kidney Allografts: A Noninvasive and Clinically Highly Relevant Marker for the Detection of Acute Rejection. AJR Am J Roentgenol. 2020 Jul;215(1):148-152. doi:10.2214/AJR.19.22128. Epub 2020 Feb 25. PMID:32097029.
Wiegley N, Walavalkar V, Aujla H, Chen LX, Huang Y, Lee BK, Jen KY. Clinicopathologic Characteristics of JC Virus Nephropathy in Kidney Transplant Recipients. Transplantation. 2020 Jun 17. doi:10.1097/TP.0000000000003363. Epub ahead of print. PMID:32639410.
Rose Li Y, Halliwill KD, Adams CJ, Iyer V, Riva L, Mamunur R, Jen KY, Del Rosario R, Fredlund E, Hirst G, Alexandrov LB, Adams D, Balmain A. Mutational signatures in tumours induced by high and low energy radiation in Trp53 deficient mice. Nat Commun. 2020 Jan 20;11(1):394. doi:10.1038/s41467-019-14261-4. PMID:31959748.
Fereidouni F, Todd A, Li Y, Chang CW, Luong K, Rosenberg A, Lee YJ, Chan JW, Borowsky A, Matsukuma K, Jen KY, Levenson R. Dual-mode emission and transmission microscopy for virtual histochemistry using hematoxylin- and eosin-stained tissue sections. Biomed Opt Express. 2019 Nov 26;10(12):6516-6530. doi:10.1364/BOE.10.006516. PMID:31853414.
Ginley B, Lutnick B, Jen KY, Fogo AB, Jain S, Rosenberg A, Walavalkar V, Wilding G, Tomaszewski JE, Yacoub R, Rossi GM, Sarder P. Computational Segmentation and Classification of Diabetic Glomerulosclerosis. J Am Soc Nephrol. 2019 Oct;30(10):1953-1967. doi:10.1681/ASN.2018121259. Epub 2019 Sep 5. PMID:31488606.
Gao G, Chen LX, Brown IE, De Mattos A, Perez RV, Jen KY. Donor Characteristics, Recipient Outcomes, and Histologic Findings of Kidney Allografts With Diffuse Donor-derived Glomerular Fibrin Thrombi. Transplantation. 2019 Sep;103(9):1921-1927. doi:10.1097/TP.0000000000002578. PMID:30720684.
Chen LX, Francalacci LC, Bang H, De Mattos A, Perez RV, Jen KY. Histopathologic Findings on Implantation Renal Allograft Biopsies Correlate With Kidney Donor Profile Index and 30-Day Serum Creatinine. Transplant Proc. 2019 Apr;51(3):639-646. doi:10.1016/j.transproceed.2018.12.027. Epub 2019 Jan 10. PMID:30979446.
Lutnick B, Ginley B, Govind D, McGarry SD, LaViolette PS, Yacoub R, Jain S, Tomaszewski JE, Jen KY, Sarder P. An integrated iterative annotation technique for easing neural network training in medical image analysis. Nat Mach Intell. 2019 Feb;1(2):112–119. doi:10.1038/s42256-019-0018-3.
Cascio MJ, Jen KY. Cocaine/levamisole-associated autoimmune syndrome: a disease of neutrophil-mediated autoimmunity. Curr Opin Hematol. 2018 Jan;25(1):29-36. doi:10.1097/MOH.0000000000000393. PMID:29211697.
