The MPSR provides a wide variety of clinical and preclinical translational services as summarized below. Please inquire for costs.


The MPSR works to develop and implement translation/correlative study components for clinical trial protocol. The MPSR will coordinate and manage all specimen collection and processing for the trial PI.

Protocol and Study Development

  • Specimen collection protocols and language
  • Development of hypotheses and objectives for translational studies
  • Development of novel biomarker assays
  • HIPAA compliance
  • Budget development

Specimen Acquisition

  • Collection and processing of specimens
  • Specimen log-in, de-identification and storage
  • Provide periodic updates on specimen accrual to study PI

Specimen Analysis

  • Coordinate or perform specimen biomarker analysis
    • DNA mutations
    • RNA expression
    • Polymorphism
    • Plasma protein/nucleotide profiling
    • Immunohistochemistry, multispectral imaging
  • Data synthesis and analysis


The shared resource can develop a comprehensive analysis plan for in vitro and in vivo testing of novel agents or therapeutic combinations for discovery and proof-of-principle. Such studies can provide rationale for clinical trial development. A wide variety of molecular biology, cell culture and xenograft assays can be provided.

  • Novel biomarker assay development
  • Preclinical modeling
    • Novel agent activity
    • Synergy testing
    • Target validation