The Mouse Biology Shared Resource (MBSR) provides unique, sophisticated, and comprehensive knockout, transgenic, and humanized murine cancer models and related services for advancing translational cancer research. Additionally, the MBSR offers services to enhance the use of existing mouse models or to facilitate the development of new mouse models for cancer research, including genetic alteration (e.g., CRISPR/Cas9-mediated gene targeting, transgenesis), surgical manipulation (e.g., patient-derived xenografts (PDX), cell-derived allografts (CDA) and xenografts (CDX)), and environmental challenges (e.g., diet, chemotherapeutic agents).
The MBSR has over 26 years of experience creating and studying genetically modified, PDX and other types of mouse models for use in cancer studies.
It has the ability to produce a wide range of allele-specific mouse models to help you achieve your research objectives. The MBSR also offers innovative technologies to phenotype mouse models that mimic human conditions.
In addition to mouse models of cancer, the MBSR provides scientific and technical consultation on experimental design and planning, as well as project and mouse colony management services for cancer researchers. Furthermore, the MBSR provides opportunities for training in procedures using mice for cancer research. Finally, the MBSR provides letters of support for grant applications and can assist researchers with methods and analysis of testing results for publications. The full spectrum of MBSR services includes
Our facility features state-of-the-art technology to support your cancer research investigations. Instrumentation includes:
For more details about the rate, please contact: 530-754-MBSR
Members of the cancer center receive priority access and subsidized rates for Shared Resources services. Not yet a member? Learn about the benefits and privileges of cancer center membership.
The MBSR can accommodate unique service requests. Let us assist you and further your research. Fill out a request to use our services.
NOTE: A PPMS account is required. View our quick start guide for creating an account or set up an account.
Director: Kent Lloyd, D.V.M., Ph.D.
Have questions about the Mouse Biology Shared Resource? Feel free to call 530-754-MBSR.
Location
UC Davis Mouse Biology Program
2795 2nd St, Suite 400
Davis, CA 95618
CCSG and MBSR Acknowledgement: the authors wish to acknowledge the support of the UC Davis Comprehensive Cancer Center Mouse Biology Shared Resource, supported by the National Cancer Institute of the National Institutes of Health under award number P30CA093373. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.
This resource is funded by the Cancer Center Support Grant (CCSG) awarded by the National Cancer Institute (NCI P30CA093373). Publications that have utilized facility resources, services or scientific data generated by the resource should acknowledge the resource or the assistance provided by resource staff and cite the NCI CCSG. An electronic copy of the publication should also be sent to the resource directors.