Research
Cancer Center Shared Resources
In Vivo Translational Imaging (IVTSR)
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The IVTISR’s advanced imaging capabilities help investigators understand the basic mechanisms of cancer and translate their findings to the clinic. We assist in every aspect of cancer imaging studies, from design and protocol development to regulatory approvals, image acquisition and high-end image analysis. Our capabilities include imaging studies of in animals and humans.
Our faculty members have expertise in all aspects of in vivo translational imaging, including:
- Animal models
- Comparative pathology
- Image analysis
- Machine learning
- Medical physics
- Preclinical and clinical radiology
- Radiochemistry
Services
We support researchers in planning, executing and analyzing in vivo imaging studies. Grant writing support is available from all Shared Resources, including support letters, recommendation, statistical analysis, etc. Our imaging and translational science services include:
Access to In Vivo Imaging Technologies
Our imaging capabilities include:
- Anatomic imaging with CT and MRI
- Molecular PET and optical imaging
- Quantitative physiologic imaging with ultrasound
- Targeted imaging probes and tracers, especially for PET imaging for animals and humans
Education and Training
The IVTISR’s faculty offer training and assistance in imaging study design, equipment operation and image analysis. We also provide training videos, classroom teaching, hands-on training and support for fellowship and trainee grant applications.
Facilities and Instrumentation
The IVTISR utilizes three state-of-the-art imaging facilities for preclinical and human imaging:
The CMGI is a vital hub for innovation in medicine and cancer research, imaging and biomedical engineering. The center supports the development and implementation of advanced imaging protocols and innovative imaging technologies, techniques and instrumentation. The CMGI also partners with the Veterinary Diagnostic Imaging Service to provide large animal imaging services.
Researchers have access to our state-of-the-art radiochemistry suite and the following in vivo imaging technologies and instrumentation:
- Biomedical Cyclotron RDS 111 (Siemens)
- Hot cells for customized PET radiotracer synthesis (Von Galen)
- Biospec 7T MRI (Bruker)
- Fluorescence Imaging Cryomicrotome (Barlow Scientific)
- Focus 120 PET (Siemens)
- Gamma Counter Wallac 1470 (Perkin Elmer)
- GNEXT PET (Sofie Biosciences)
- Inveon® DPET (Siemens)
- IVIS™ Spectrum Optical Imaging (Perkin Elmer)
- MicroXCT-200 (XRadia)
- Phosphor Imager STORM 860 (Amersham Biosciences)
- SimPET™ 1.5T M7 MRI (Aspect Imaging)
CMGI has a partnership with the Veterinary Diagnostic Imaging Service to provide large animal imaging services.
The EMIC is built around the first FDA-cleared total-body PET/CT scanner. The scanner features unpreceded signal collection efficiency and a spatial resolution of up to 3 millimeters. This allows researchers to obtain excellent image quality for numerous clinical and research applications.
The EMIC’s comprehensive infrastructure includes:
- Four dedicated injection rooms
- Metabolic laboratory featuring a high-performance liquid chromatography (HPLC) system and an automatic gamma counter
- Radiopharmaceutical laboratory (“hot lab”)
- Research laboratory
Rates
View the recharge rates for each IVTISR Center:
Request IVTISR Services
Let us support your cancer research study with state-of-the-art imaging capabilities. Fill out a request for IVTISR services.
NOTE: A PPMS account is required. View our quick start guide for creating an account or set up a PPMS account.
Contact the IVTISR
For questions about our services, please contact:
Abhijit Chaudhari, Ph.D.
Co-Director
Email: ajchaudhari@ucdavis.edu
Lorenzo Nardo, M.D., Ph.D.
Co-Director
Email: lnardo@ucdavis.edu
Locations
Center for Molecular and Genomic Imaging (CMGI)
Genome and Biomedical Sciences Facility
451 Health Science Dr.
Davis, CA 95616
EXPLORER Molecular Imaging Center (EMIC)
UC Davis School of Medicine
Department of Radiology
4860 Y Street, Suite 3000
Sacramento, CA 95817
Imaging Research Center (IRC)
UC Davis School of Medicine
4701 X Street, Suite 3000
Sacramento, CA 95817
Policies for IVTISR Services
Please read our policies on using IVTISR and its imaging facilities:
- Operations: Daily operations within each of the three facilities are overseen by the designated operational director for that facility.
- Access: Access to each facility usually happens on a first-come, first-served basis. You may request modified scheduling from the facility director to accommodate reasonable investigator deadlines.
- Priority: Faculty members conducting small-scale studies to include pilot data for external funding proposals receive scheduling priority and additional technical assistance.
- Use of multiple facilities: When a single imaging study uses two or more facilities, technical staff from each facility will discuss coordination of effort beforehand.
