Hsin-Yi Henry Ho, Ph.D.
Associate Professor of Cell Biology and Human Anatomy
Locations and Contact
Additional Numbers
Physician Referrals
Research/Academic Interests
Dr. Ho's research group studies the molecular and cellular mechanisms of embryonic development, and how mutations give rise to congenital disorders such as dwarfism, cleft palate and neural tube defect.
Division
Cell Biology and Human Anatomy
Center/Program Affiliation
Undergraduate School
B.S., Biochemistry, UCLA, Los Angeles CA 1998
Other School
Ph.D., Cell and Developmental Biology, Harvard Medical School, Boston MA 2004
Fellowship
Neurobiology, Boston Children's Hospital/Harvard Medical School, Boston MA 2004-2013
The Maximizing Investigators' Research Award (MIRA), NIH, 2016
Damon Runyon Cancer Research Foundation Fellowship, 2006
Konopelski Snavely SE, Srinivasan S, Dreyer CA, Tan J, Carraway KL 3rd, Ho HH. Non-canonical WNT5A-ROR signaling: New perspectives on an ancient developmental pathway. Curr Top Dev Biol. 2023;153:195-227. doi:10.1016/bs.ctdb.2023.01.009. Epub 2023 Mar 17. PMID:36967195.
Konopelski Snavely SE, Susman MW, Kunz RC, Tan J, Srinivasan S, Cohen MD, Okada K, Lamb H, Choi SS, Karuna EP, Scales MK, Gygi SP, Greenberg ME, Ho HH. Proteomic analysis identifies the E3 ubiquitin ligase Pdzrn3 as a regulatory target of Wnt5a-Ror signaling. Proc Natl Acad Sci U S A. 2021 Jun 22;118(25):e2104944118. doi:10.1073/pnas.2104944118. PMID:34135125.
Mansour TA, Lucot K, Konopelski SE, Dickinson PJ, Sturges BK, Vernau KL, Choi S, Stern JA, Thomasy SM, Döring S, Verstraete FJM, Johnson EG, York D, Rebhun RB, Ho HH, Brown CT, Bannasch DL. Whole genome variant association across 100 dogs identifies a frame shift mutation in DISHEVELLED 2 which contributes to Robinow-like syndrome in Bulldogs and related screw tail dog breeds. PLoS Genet. 2018 Dec 6;14(12):e1007850. doi:10.1371/journal.pgen.1007850. PMID:30521570.
Susman MW, Karuna EP, Kunz RC, Gujral TS, Cantú AV, Choi SS, Jong BY, Okada K, Scales MK, Hum J, Hu LS, Kirschner MW, Nishinakamura R, Yamada S, Laird DJ, Jao LE, Gygi SP, Greenberg ME, Ho HH. Kinesin superfamily protein Kif26b links Wnt5a-Ror signaling to the control of cell and tissue behaviors in vertebrates. Elife. 2017 Sep 8;6:e26509. doi:10.7554/eLife.26509. PMID:28885975.