General Medicine and Bioethics Research | Department of Internal Medicine | UC Davis Health

Specialties

General Medicine and Bioethics

General Medicine and Bioethics Research

Dr. Erin Noren presents a poster at the 2025 Internal Medicine Research Symposium to a man in a blue shirt.

The UC Davis Health Division of General Medicine and Bioethics is committed to improving patient outcomes and quality of care through innovative research that meets current community needs. Our research addresses health outcome disparities, the primary care provider shortage, opioid addiction and pain management, while prioritizing patient autonomy and ensuring adherence to bioethical standards. Funding for our research is provided by the National Institute for Health (NIH), the National Heart, Lung, and Blood Institute (NHLBI), the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), the National Institute on Aging (NIA), Centers for Disease Control and Prevention (CDC), the American Medical Association (AMA), and UC Davis Health. 

Some of our current research projects include investigating: 

  • Overdose in patients co-prescribed opioids and benzodiazepines.
  • Tobacco control policy and cessation, focusing on health services delivery of tobacco treatment, interventions to address tobacco/cancer disparities, and the behavioral impact of smoke and tobacco-free policies.
  • Accelerated competency-based education in primary care programs to address the primary care provider shortage.
  • Disparities in rural health and education in Northern California and Oregon (COMPADRE).
  • Guideline-recommended diabetes testing after gestational diabetes mellitus (GDM) (SUNRISE).
  • Motivational determinants of postpartum lifestyle behaviors, weight retention, and metabolic syndrome (PETALS-2).
  • The effects of visit characteristics on patient-clinician interactions and health outcomes in knee osteoarthritis.
  • The role of bilingualism in cognitive resilience, aging and dementia.
Research Spotlight

Addressing the Primary Care (PC) Physician Shortage

As the region’s only academic health center, a core mission of UC Davis is to meet the Primary Care (PC) workforce needs of California’s rural and urban counties. 

Five presenters stand and pose at the front of a lecture hall.
Latest Publications
  • February 2026

    Meaningful Interactional Diversity, Professional Development, and Service Intent

    This cross-sectional study evaluates whether White medical students’ experience of meaningful interactional diversity—the experience of changing one’s knowledge or opinions as a result of encountering the perspectives of individuals from different backgrounds—is associated with personal and professional competencies as well as plans to work with underserved populations. 

    Shruthi Venkataraman, Mytien Nguyen, Alexandra M. Hajduk, Adeola Ayedun, Will Roberts, Bassel Shanab, Allison Aviles, Nhu Y. Doan, Meghan O’Connell, Soo-Min Shin, Gbenga Ogedegbe, David Henderson, Somnath Saha, Jeph Herrin, Tonya Fancher, Sarwat I. Chaudhry, Dowin Boatright. Meaningful Interactional Diversity, Professional Development, and Service Intent in White Medical Students. JAMA Network Open (2026) 9(2):e2560266. 10.1001/jamanetworkopen.2025.60266 
    Open Access
  • February 2026

    Rift Valley fever vaccines for animals and people

    Rift Valley fever (RVF) is a zoonotic viral disease transmitted by mosquitoes, that causes significant impacts on animal health, public health, and socio-economic wellbeing in affected areas. Although RVF vaccines for livestock are available and human vaccines are currently under development, a coordinated One Health approach to vaccination has yet to be fully explored. This mini-review article aims to examine RVF vaccination strategies from a One Health perspective. 

    Ana Pérola D. Brandão, Woutrina A. Smith, Grace W. Mwangoka, Shelby M. Cagle, Sharif S. Aly, Robert D. Sumaye, Rebekah C. Kading, Michael S. Wilkes, MacDonald W. Farnham, Nicole C. Kelp, Rosemarie E. Scharf, Jeffrey S. Hoch, Maxmillian G. Mpina and Brian H. Bird. Rift Valley fever vaccines for animals and people: Envisioning One Health vaccination strategies. CABI One Health (2026) 5:1, 0005 https://doi.org/10.1079/cabionehealth.2026.0005 
    Open Access
  • January 2026

    The Stress Management and Resiliency Training (SMART) Program

    Participation in the SMART Program was associated with significant improvements in clinician well-being that persisted six months following program completion and was positively associated with the number of stress-management tools used and meditation practice.

    Brittany L. Garcia, Maureen A. Craig, Nicole Adams, Elyse R. Park, Michelle Dossett (2026). The Stress Management and Resiliency Training (SMART) Program Is Associated with Sustained Improvement in Clinician Well-Being: Results from an Observational Cohort Study. International Journal of Environmental Research and Public Health 23(2): 161. doi.org/10.3390/ijerph23020161
    Open Access
  • January 2026

    Circulating neurodegenerative brain injury markers and fall hospitalizations

    Individuals with dementia have a heightened hip fracture and fall risk but whether markers of brain injury are associated with hip fracture and falls is unknown. This study tested the hypothesis that higher circulating brain injury markers were associated with increased risk of hip fracture and fall hospitalizations.

    Jane A Cauley, Petra Buzkova, Howard A Fink, Joshua I Barzilay, Rachel E Elam, Oscar L Lopez, Lauren Carlson, John A Robbins, Luc Djousse, Kenneth J Mukamal (2026). Circulating neurodegenerative brain injury markers and hip fracture and fall hospitalizations: the Cardiovascular Health Study. Journal of Bone and Mineral Research 41(1), pp. 38-45.
    Open Access
  • January 2026

    Extracting language information from clinical notes using large language models

    This study developed and evaluated a named entity recognition (NER) framework that enables automated extraction of nuanced language information from clinical narratives with high accuracy and generalizability. This work supports large-scale, language-focused research and has practical implications for improving patient-provider communication, interpreter service allocation, and equitable healthcare delivery.

    Lingfei Qian, Na Hong, Yujia Zhou, Qianqian Xie, Ruey-Ling Weng, Pitchaya Chairuengjitjaras, Xinsong Du, John Lian, Gad A. Marshall, Suzanne V. Blackley, John Novoa-Laurentiev, Yakeel T. Quiroz, Tae Youn Kim, Nicole Adams, Michelle L. Dossett, Li Zhou, Hua Xu (2026). Extracting language information from clinical notes using large language models. International Journal of Medical Informatics. doi.org/10.1016/j.ijmedinf.2025.106116
    Open Access
  • December 2025

    How Do We Honor Identities in Medical Education?

    Commentary on Yang et al., 2025: Underrepresentation of Filipino, Laotian, Cambodian, and Indonesians Among US Allopathic Medical Students.

    Tonya L. Fancher, Jonathan Credo, Stephany Sanchez (2025). How Do We Honor Identities in Medical Education? Journal of General Internal Medicine. doi.org/10.1007/s11606-025-10085-9
    Open Access
  • December 2025

    Dose trajectories associated with non-fatal overdose

    This retrospective cohort study assesses opioid and benzodiazepine prescribing trajectories associated with overdose. For both opioids and benzodiazepines, overdose risk was increased with both decreasing and increasing short-term and long-term trajectories relative to stable doses.

    Joshua J. Fenton, Shao-You Fang, Susan Stewart, Iraklis Erik Tseregounis, Alicia Agnoli, James J. Gasper, Stephen G. Henry (2025). Dose trajectories associated with non-fatal overdose among patients co-prescribed opioids and benzodiazepines: Retrospective cohort study. Drug and Alcohol Dependence. doi.org/10.1016/j.drugalcdep.2025.112928
    Open Access
  • November 2025

    Medical student and faculty perceptions of learning from pediatric patients

    While the value of medical student involvement in the care of pediatric patients is widely recognized, challenges and risks may limit learning. Given the need for students to gain this specific skillset, programs must develop strategies to ensure learning occurs in ways that maximize the benefits to children and families.

    Jennifer Plant, Mark Fedyk, Zachary Chaffin, Efrat Lilkes, Colleen Sweeney, Adam Weinstein, Lavjay Butani (2025). Medical student and faculty perceptions of learning from pediatric patients and families: a multicenter qualitative study. Academic Pediatrics. doi.org/10.1016/j.acap.2025.103173
    Open Access
  • November 2025

    Challenges of Conducting Risk-Benefit Analysis of Early Phase Clinical Trials

    Institutional review boards (IRBs) are charged with conducting risk-benefit analysis for early phase clinical trials that often involve high levels of uncertainty regarding a trial's potential risks and benefits. Our study used a survey of IRB chairs to explore how IRBs conduct risk-benefit analysis, the unique facets of risk-benefit analysis for early phase clinical trials and specifically for early phase neurology trials, and what facilitates high-quality risk-benefit analysis.

    Christine M. BaughDragana Bolcic-JankovicMark FedykMark YarboroughSpencer Phillips HeyInsoo HyunJonathan KimmelmanEric G. Campbell (2025). Challenges of Conducting Risk-Benefit Analysis of Early Phase Clinical Trials: Results of a National Survey of IRB Chairs. Ethics & Human Research 47(6): pp. 2-12. doi.org/10.1002/eahr.60024
    Open Access
  • November 2025

    Multinational physician perspectives on abortion care

    Since Dobbs v. Jackson Women's Health Organization (2022) overturned Roe v. Wade (1973), thus returning abortion policy decisions to state governments, abortion access across the United States became fragmented, with some states enacting near-total bans and other states strengthening protection. As a parallel, the Republic of Ireland's (ROI) 2018 repeal of the Eighth Amendment and the United Kingdom's (UK) longstanding framework of care offer informative historical examples. This qualitative study explores the perspectives and experiences of abortion-trained physicians in California (CA), Texas (TX), ROI, and the UK, focusing on how legislation shapes physicians' ability to deliver comprehensive abortion care.

    Emilie S. Allaert, Caroline C. Liu, Katherine Liu, Anna T. Truong, Michael S. Wilkes (2025). Multinational physician perspectives on abortion care in the context of changing legislation. Frontiers of Global Women’s Health. doi.org/10.3389/fgwh.2025.1581704
    Open Access