Joseph Tuscano, M.D.

Joseph Michael Tuscano, M.D.


Bone Marrow Transplant



Internal Medicine


  • Professor


To see if Joseph Michael Tuscano is accepting new patients, or for assistance finding a UC Davis doctor, please call 800-2-UCDAVIS (800-282-3284).

UC Davis Comprehensive Cancer Center

2279 45th Street
Sacramento, CA 95817
Driving Directions

Primary Phone:

Additional Phone Numbers

Clinic Phone: 916-734-5981
Physician Referrals: 800-4-UCDAVIS (800-482-3284)

Clinical Interests

Dr. Tuscano's areas of specialty include the treatment of leukemia, lymphoma, MDS, and multiple myeloma. He is also a member of the adult stem cell transplant team. 

Research/Academic Interests

Dr. Tuscano has both basic/translation and clinical research interests that include the development of novel antibody and other immune-based therapeutics for hematologic malignancies.


Hematology and Oncology

Center/Program Affiliation

Stem Cell Transplant Program
UC Davis Comprehensive Cancer Center
Stem Cell Research Program


M.D., University of Southern California School of Medicine, Los Angeles CA 1989

B.S., California State University, Sacramento, Sacramento CA 1985

Internship: Internal Medicine, UC Davis Medical Center, Sacramento CA 1989-1992


Internal Medicine, UC Davis Medical Center, Sacramento CA 1989-1992


Hematology/Oncology, National Institutes of Health, National Cancer Institute, Bethesda MD 1992-1994

Hematology/Oncology, National Institutes of Health, National Cancer Institute, Bethesda MD 1994-1996

Hematology/Oncology, UC Davis Medical Center, Sacramento CA 1997-1998

Board Certifications

American Board of Internal Medicine, Medical Oncology,

Professional Memberships

American Association of Immunologists (AAI)

American Society of Blood and Marrow Transplantation

American Society of Clinical Oncology

American Society of Hematology

Southwest Oncology Group, Myeloma and Lymphoma Committees

Honors and Awards

Certificate of Appreciation: The Leukemia & Lymphoma Society, 2009

Cure for Lymphoma Foundation Distinguished Researcher, 1999

Christine Landgraff Memorial Cancer Research Award - UCD, 1998

Faculty-Physician of the Year, Nominated UCD Medical Center, 1999

Fellowship - NIH Fellows Award for Research Excellence, 1992, 1993, 1994

Medical School-Honors in Hematology, Endocrinology, Medicine, 1989

Undergraduate-Deans Scholar, 1985

Select Recent Publications

For a comprehensive list of Dr. Tuscano's publications, please click here (opens new window).

Franke PH, Chung V, Tuscano J, Siddiqi T, Sampath S, Longmate J, Groshen S, Newman EM. Model of a Queuing Approach for Patient Accrual in Phase 1 Oncology Studies. JAMA Network Open. 2020 May;3(5):e204787. doi:10.1001/jamanetworkopen.2020.4787.

Hoeg RT, Davis J, Jonas BA, Tuscano J, Rosenberg A, Abedi M. A Phase I Study of Everolimus and Bendamustine in Patients With Relapsed/Refractory Lymphoid Hematologic Malignancies. Clinical Lymphoma Myeloma and Leukemia. 2020 Feb;20(7):453-458. Doi:10.1016/j.clml.2020.2.006.

Tuscano J, Maverakis E, Groshen S, Tsao-Wei D, Luxardi G, Merleev A, Beaven A, DiPersio J, Popplewell L, Chen R, Kirschbaum M, Schroeder M, Newman E. A Phase I Study of the Combination of Rituximab and Ipilimumab in Patients with Relapsed/Refractory B-Cell Lymphoma. Clin Cancer Res. 2019 Dec 1;25(23):7004-7013. doi: 10.1158/1078-0432.CCR-19-0438.  Epub 2019 Sep 3.

Takebe N, Beumer J, Kummar S, Kiesel B, Dowlati A, Coyne G, Piekarz R, Rubinstein L, Fogli L, Vaishampayan U, Goel S, O'Bryant C, El-Rayes B, Chung V, Lenz H, Kim R, Belani C, Tuscano J, Schelman W, Moore N, Doroshow J, Chen A. A phase I pharmacokinetic study of belinostat in patients with advanced cancers and varying degrees of liver dysfunction. Br J Clin Pharmacol. 2019 Nov;85(11): 2499-2511. doi:10.1111/bcp.14054. Epub 2019 Sep 4.

Tomlinson B, Tuscano J, Abedi M, Welborn J, Arora M, O'Donnell R, Wun T, Jonas B. A phase II study of bortezomib in combination with pegylated liposomal doxorubicin for acute myeloid leukemia. Am J Hematol. 2019 Nov;94(11):e291-294.

Vogel CFA, Ishihara Y, Campbell CE, Kado SY, Nguyen-Chi A, Sweeney C, Pollet M, Haarmann-Stemmann T, Tuscano JM. A Protective Role of Aryl Hydrocarbon Receptor Repressor in Inflammation and Tumor Growth. Cancers (Basel). 2019 May;11(5):589. Published online 2019 Apr 27. doi:10.3390/cancers11050589.

McHardy I, Romanelli A, Harris LJ, Opp G, Gaudino R, Torres A, Polage CR, Tuscano JM, Thompson GR. Infectious risks associated with medicinal Cannabis: Potential implications for immunocompromised patients? J Infect. 2018 May;76(5):500-501. doi:10.1016/j.jinf.2018.01.010. Epub 2018 Feb 13.

Kirschbaum M, Frankel P, Synold T, Zain J, Claxton D, Tuscano J, Newman E, Gandara D, Lara P. A phase II study of vascular endothelial growth factor trap (Aflibercept, NSC 724770) in patients with myelodysplastic syndrome: a California Cancer Consortium Study. Br J Haematol. 2018 Feb;180(3):445-448. doi:10.1111/bjh.14333. Epub 2016 Sep 21.

Barisone GA, O'Donnell RT, Ma Y, Abuhay MW, Lundeberg K, Gowda S, Tuscano JM. A purified, fermented, extract of Triticum aestivum has lymphomacidal activity mediated via natural killer cell activation. PloS one. 2018;13(1):e0190860. Published online 2018 Jan 5. doi:10.1371/journal.pone.0190860

Yoshida S, Tuscano E, Duong C, Chung J, Li Y, Beckett L, Tuscano JM, Satake N. Efficacy of an anti-CD22 antibodymonomethyl auristatin E conjugate in a preclinical xenograft model of precursor B-cell acute lymphoblastic leukemia. Leukemia & Lymphoma. 2017 May;58(5):1254-1257. doi:10.1080/10428194.2016.1235273. Epub 2016 Oct 5.