Undergraduate School

B.A., Beijing Medical University, Beijing, China 1984

Medical School

M.D., Ph.D., Beijing Medical University, Beijing, China 1989

Fellowship

M.D., Postdoctoral Fellow, Anderson Cancer Center, TX 1991

VA Research Career Scientist Award, 2022-2027,

Advisory Council Member, NIH, NIAMS, 2012, 2013, 2014,

William Montagna Award, Society of Investigative Dermatology, (one awardee worldwide each year to give a scientist who has made a significant contribution to skin biology research), 2014,

State-of-the-Art lecture, Society of Investigative Dermatology, 2006,

“Career Development Award” from the Dermatology Foundation, 1997,

For a complete list of Dr. Wang's publications, please click here. 

Lind HT*, Hall SC*, Strait AA*, Goon JB*, Aleman JD*, Chen SMY, Karam SD, Young CD, Wang JH, Wang XJ (2025). MHC class I upregulation contributes to the therapeutic response to radiotherapy in combination with anti-PD-L1/anti-TGF-β in squamous cell carcinomas with enhanced CD8 T cell memory-driven response. Cancer Letters, 2025 Jan 1:608:217347. PMID: 39580046, PMCID: PMC11875078

Li X*, Ke Y, Hernandez AL*, Yu J, Bian L, Hall SC*, Nolan K, Wang JH, Young CD, Wang XJ (2023). Inducible nitric oxide synthase (iNOS)-activated Cxcr2 signaling in myeloid cells promotes TGFβ-dependent squamous cell carcinoma lung metastasis. Cancer Lett. 2023 Aug 28;570:216330. doi: 10.1016/j.canlet.2023.216330. Epub 2023 Jul 29. PMID: 37524225 PMCID: PMC10530117 

Ke Y, Li BZ, Nguyen K, Wang D, Wang S, Young CD, Wang XJ (2023). IL22RA2 is a Smad7 target mediating alleviation of dermatitis and psoriatic phenotypes in mice. JID, 2023 Nov;143(11):2243-2254. PMID: 37211203, PMCID: PMC11127768

Strait AA*, Woolaver RA*, Hall S*, Young CD, Karam SD, Jimeno A, Lan Y, Raben D, Wang JH, Wang XJ (2021). Distinct immune microenvironment profiles of therapeutic responders emerge in combined TGFβ/PD-L1 blockade-treated squamous cell carcinoma. Communications Biology, Open Access DOI 10.1038/s42003-021-02522-2

Shi X*, Luo J*, Weigel KJ, Hall SC* Du D*, Wu F*, Rudolph MC, Zhou H, Young CD, Wang XJ (2021). Cancer-associated fibroblasts facilitate squamous cell carcinoma lung metastasis in mice by providing TGFß-mediated cancer stem cell niche. Frontiers in Cell and Developmental Biology, open access Aug 30: doi: 10.3389/fcell.2021.668164 

Woolaver RA*, Wang X, Krinsky AL, Waschke BC, Chen SMY, Popolizio V, Nicklawsky AG, Gao D, Chen Z, Jimeno A, Wang XJ, Wang JH (2021). Differences in TCR repertoire and T cell activation underlie the divergent outcomes of anti-tumor immune responses in tumor-eradicating versus tumor-progressing hosts. Journal for ImmunoTherapy of Cancer, 2021;9:e001615. doi:10.1136/jitc-2020-001615

Hernandez AL*, Young, C.D., Bian, L., Weigel, K. Nolan, K., Frederick, B., He, G., Jones, K.L., Rudolph, M.C., Trahan, G.D., Oweida, A.J., Karam, S.D., Raben, D., Wang, X.J (2020). PARP inhibition enhances radiotherapy of SMAD4 deficient human head and neck squamous cell carcinomas in experimental models. Clinical Cancer Research. 2020. Epub 03/05/2020. doi: 10.1158/1078-0432.CCR-19-0514, PubMed PMID: 32139402.

Han G, Bian L, Li F*, Cotrim A, Wang D, Lu JB, Deng Y, Bird G, Sowers A, Mitchell J, Gutkind JS, Zhao R, Raben D, ten Dijke P, Refaeli Y, Zhang QH, and Wang XJ (2013). Preventive and therapeutic effects of Smad7 on radiation-induced oral mucositis. Nat Med, 19: 421-428 (highlighted by Nat Med Podcast, April, 2013)

White RA*, Neiman JM*, Reddi A, Han G, Birlea S, Mitra D, Dionne L, Fernandez P, Murao K, Bian L, Keysar SB, Goldstein NB, Song N, Bornstein S, Han Z, Lu X, Wisell J, Li F, Song J, Lu SL, Jimeno A, Roop DR, Wang XJ (2013). Epithelial stem cell mutations that promote squamous cell carcinoma metastasis. J Clin Invest. 123(10):4390-404, PMID: 23999427

Hoot KE*, Oka M, Han G, Bottinger E, Zhang Q, and Wang XJ (2010). HGF Upregulation Contributes to Angiogenesis in Mice with Keratinocyte-Specific Smad2 Deletion. J Clin Invest, 120:3606-16.