Kenneth Iczkowski, M.D.
Professor
To see if Kenneth Iczkowski is accepting new patients, or for assistance finding a UC Davis doctor, please call 800-2-UCDAVIS (800-282-3284).
Specialties
Pathology
Pathology - Surgical
Pathology - Cardiovascular
Pathology - Transplant
Pathology - Urologic
Department
Locations and Contact
Additional Numbers
Phone
Philosophy of Care
I use my experience and resources to give the most comprehensive care to urological patients, including the use of current diagnostic standards and technologies.
Clinical Interests
Dr. Iczkowski is the head of urological anatomic pathology, also practicing cardiovascular (heart transplant) and general pathology. He is a diagnostic consultation resource for prostate, bladder, testicular, kidney, and penile cancers. He has special interest and expertise in grading criteria for prostate cancer, use of artificial intelligence and machine learning in pathology, and spatial transcriptomics to correlate molecular and histologic findings.
Research/Academic Interests
Dr. Iczkowski's research focuses on pathologic - radiologic correlation using artificial intelligence to match microscopic findings in the prostate with radiological findings. Current collaborations involve therapeutic targeting of bladder cancer. He also has a background in basic science research for prostate cancer, including cell adhesion molecules and pathways involved in growth and metastasis.
Division
Anatomic Pathology
Center/Program Affiliation
Undergraduate School
B.A., Biology, Columbia College of Columbia University, 1986
Medical School
M.D., Medicine, St. Louis University, 1992
Residency
Pathology, Dartmouth-Hitchcock Medical Center, 1992-95
Fellowship
Anatomic Pathology, University of Kansas, 1995-96
Fellowship
Urological Pathology, Mayo Clinic Rochester, 1997-98
Faculty Teacher of the Year plaque. Medical College of Wisconsin, 2021-2022. “In recognition of outstanding educational contributions to the Department of Pathology”, 2022
Outstanding Medical Student Teacher, 2016-2017, and 2014-2015, Medical College of Wisconsin (Curriculum and Evaluation Committee),
Paul Albert Grawitz medal awarded by International Society of Urological Pathology “For distinguished service”, 2013
Distinction in Research Award, and Herbert B. Taylor Award in Pathology, St. Louis University School of Medicine, 1992,
Good Catch Award, Pathology at UC-Davis (diagnostic error prevented), 2025,
For a list of Dr. Iczkowski's publications, see https://pubmed.ncbi.nlm.nih.gov/?term=iczkowski
Iczkowski KA, et al. International Society of Urological Pathology Consensus on Cancer Precursor Lesions. Working Group 1: The Prostate, American Journal of Surgical Pathology. March 5, 2025.
Nguyen NNJ, Liu K, Lajkosz K, Bernardino R, Yin LB, Hollemans E, Kroon LJ, Fleshner N, van Leenders GJLH, Iczkowski KA, van der Kwast TH, Downes MR. MRI-adapted prostate cancer risk tool incorporating cribriform and intraductal carcinoma. Revision for Modern Pathology, 2025.
Iczkowski, K.A. Optimizing biopsy core quality for diagnosis. Chapter 22 in Imaging and Focal Therapy of Early Prostate Cancer, eds. Polascik TJ, de la Rosette J, Sanchez-Salas R, and Rastinhad A. London: Springer Nature, 2024; DOI:10.1007/978-3-031-66754-1.
Shah RB, Paner GP, Cheng L, De Marzo AM, Magi-Galluzzi C, Varma M, Zhou M, Amin A, Amin MB, Aron M, Cunha IW, Epstein JI, Fine SW, Haider A, Iczkowski KA, Kench JG, Kunju LP, Mohanty SK, Montironi R, Netto GJ, Pan CC, Rao P, Srigley JR, Sauter G, Tan RH, Tsuzuki T, van der Kwast TH, van Leenders GJ, Kristiansen G. Genitourinary Pathology Society (GUPS) and International Society of Urological Pathology (ISUP) White Paper on Defining Indolent Prostate Cancer: Call for a Multidisciplinary Approach. In Press, European Urology 2025.
Duenweg SR, Bobholz SA, Barrett MJ, Lowman AK, Winiarz A, Nath B, Stebbins M, Bukowy J, Iczkowski KA, Jacobsohn KM, Vincent-Sheldon S, LaViolette PS. T2-weighted MRI radiomic features predict prostate cancer presence and eventual biochemical recurrence. Cancers (Basel) 2023;15:4437. doi: 10.3390/cancers15184437.
Nguyen, N.N.J., Liu, K., Lajkosz, K., Iczkowski, K.A., van der Kwast, T.H., Downes, M.R. Addition of cribriform pattern 4 and intraductal prostatic carcinoma into the CAPRA-S tool improves post-radical prostatectomy patient stratification in a multi-institutional cohort. J of Clinical Pathology. 2024 Feb 20; jcp-2023-209222. doi:10.1136/jcp-2023-209222.
Karan D, Wick J, Dubey S, Kumar C, Siddiqui J, Iczkowski KA.,Chinnaiyan A. Racial differences in serum chemokines in prostate cancer patients. Cancer, 2023;129:3783-3789. doi: 10.1002/cncr.35012.
Pestell R, Li Z, Jiao X, Robertson A, Di Sante G, Ashton A, DiRocco A, Wang M, Zhao J, Addya S, Wang C, McCue P, South A, Cordon-Cardo C, Liu R, Patel K, Hamid R, Parmar J, DuHadaway J, Jones S, Casimiro M, Schultz N, Kossenkov A, Phoon LY, Chen H, Lan L, Sun Y, Iczkowski, K.A., and Rui H. The DACH1 gene is frequently deleted in prostate cancer, restrains prostatic intraepithelial neoplasia, decreases DNA damage repair, and predicts therapy responses. Oncogene. 2023 Jun;42(22):1857-1873.
Iczkowski KA, van Leenders GJLH, Tarima S, Wu R, Van der Kwast T, Berney D, Evans AJ, Wheeler TM, Ro JY, Samaratunga H, Delahunt B, Srigley J, Varma M, Tsuzuki T, Egevad L. Cribriform Prostate Cancer: Morphologic Criteria Enabling a Diagnosis, Based on Survey of Experts. Annals of Diagnostic Pathology, 2021;52:151733.
Iczkowski KA, Torkko KC, Kotnis GR, Wilson RS, Huang W, Wheeler TM, Abeyta AM, La Rosa FG, Cook S, Werahera PN, Lucia MS. Digital quantification of five high-grade prostate cancer patterns, including the cribriform pattern, and their association with adverse outcome. American Journal of Clinical Pathology, 2011;136:98-107.