Browse Topic
Cell and Gene Therapy
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March 16, 2026New training model helps surgeons practice minimally invasive spina bifida repair
Engineers at UC Davis Tech Foundry and medical professionals at UC Davis Health have developed a teaching model to train surgeons on fetoscopic repair of spina bifida.
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March 04, 2026Teenage daughter’s bone marrow saves dad’s life
After years of fearing and delaying treatment for a blood disease, Hai Trinh finally got a bone marrow transplant — from his 17-year-old child.
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February 26, 2026First-ever in-utero stem cell therapy for fetal spina bifida repair is safe, study finds
A UC Davis Health research team has safely performed the world’s first spina bifida treatment combining fetal surgery with stem cells, according to results from Phase 1 of an ongoing clinical trial. These results have been published today in The Lancet.
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February 25, 2026UC Davis medical school among nation’s best in NIH funding
The UC Davis School of Medicine is among the nation’s top-NIH funded medical schools, with about $233 in grants, in latest Blue Ridge Institute ranking
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December 08, 2025UC Davis Health designated as a NORD Rare Disease Center of Excellence
UC Davis Health is now designated as a NORD Rare Disease Center of Excellence for its leadership in providing research and expert care for people with rare diseases.
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November 18, 2025Fetal surgery at UC Davis Health gives Ohio baby new hope
A stunning diagnosis led one Ohio couple to UC Davis Children’s Hospital, where fetal surgery offered them hope for their first child.
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September 18, 2025UC Davis scientists pioneer stem cell gene therapy for Angelman syndrome
UC Davis Health researchers are testing a groundbreaking new therapy for the rare neurodevelopmental condition Angelman syndrome.
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September 03, 2025Dream team to develop in utero gene editing therapy for a rare neurological genetic disorder
Professor Aijun Wang won a $3.2 million NIH grant to develop a cure to Dup15q syndrome using an in-utero gene editing formula.
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April 29, 2025UC Davis pediatric neurosurgeon receives national award for hydrocephalus research
Pediatric neurosurgeon Cameron Sadegh was selected for a Hartwell Individual Biomedical Research Award to develop a gene therapy for hydrocephalus in premature babies.
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April 15, 2025Diana Farmer wins top national award for innovative fetal spina bifida stem cell research
A Q&A with top prenatal surgeon Diana Farmer who won the 2025 Edward H. Ahrens, Jr. Award for her work on spina bifida CuRe clinical trial.
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April 15, 2025Novel cell therapy receives expedited FDA designation
A cell therapy being evaluated at UC Davis for the treatment of oropharyngeal dysphagia following cancer treatment has been fast tracked by the FDA.
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December 04, 2024Health Net grant for UC Davis Stem Cell Program to improve access to CAR T-cell therapy
UC Davis Health’s Stem Cell Program received a grant from Health Net to improve cancer patients’ access to life-saving CAR-T therapies and clinical trials.
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November 01, 2024How understanding the secrets of herpesviruses helps fight cancer
Herpesviruses stay dormant in the body until they take over normal cell functions to replicate and cause disease. UC Davis Health researchers are learning about herpesvirus strategies and reversing them to help prevent cancer cells from growing.
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October 24, 2024Could a new medical approach fix faulty genes before birth?
A new biomedical tool successfully delivers genetic material to edit faulty genes in developing fetal brain cells. This might stop disease progression of genetic-based neurodevelopmental conditions and provide a cure by the time the baby is born.
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September 17, 2024Life-saving stem cell transplant program revitalized
UC Davis Health’s pediatric stem cell (bone marrow) transplant program is rejuvenated under new leadership.
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August 20, 2024Gut bioelectricity provides a path for bad bacteria to cause diseases
UC Davis Health researchers has discovered a novel bioelectrical mechanism pathogens like Salmonella use to find entry points in the gut lining that would allow them to pass and cause infection.
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January 31, 2024What you need to know about spina bifida and spinal cord injuries
In a Q&A, UC Davis Health physical medicine and rehabilitation specialist Maya Evans shares how clinicians and parents can provide comprehensive care for children with spinal cord injuries and spina bifida.
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January 29, 2024UC Davis Health leads study on promising stem cell-based therapy for Crohn’s disease
A stem cell therapy for Crohn's disease developed by gastroenterology researchers has shown promising results in mouse studies.
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December 19, 2023New bioengineered scaffold may help large deep burn wounds heal faster
Professor Aijun Wang has designed and tested a structure that can help large deep burn wounds heal faster and potentially reduce the need for skin autografting.
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November 29, 2023State stem cell agency, Shriners Children’s award $15 million to UC Davis CuRe trial
Fetal surgeon Diana Farmer and bioengineer Aijun Wang have been awarded $15 million by the state’s stem cell agency and Shriners Children’s to test their stem cell treatment for spina bifida.
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October 25, 2023Meet the UC Davis Good Manufacturing Practice Facility’s new homegrown leader
A Q&A with the new director of UC Davis Good Manufacturing Practice (GMP) facility Brian Fury to learn about the GMP’s plans and recent California Institute for Regenerative Medicine (CIRM) $1.7 million award.
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April 18, 2023
UC Davis Health receives 2023 Top Ten Clinical Research Achievement Award
Chair of Physical Medicine and Rehabilitation Craig McDonald was honored with a 2023 Top Ten Clinical Research Achievement Award, in recognition of his remarkable work on Duchenne muscular dystrophy.
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February 21, 2023UC Davis Health to develop in-utero therapy for Duchenne muscular dystrophy
Professor Aijun Wang won a $2 million grant from California’s Stem Cell Agency to develop a cure to Duchenne muscular dystrophy (DMD) using an in-utero gene editing formula.
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December 27, 2022UC Davis partners with Caring Cross and CIRM to develop immunotherapy for cancer patients
Immunologist William Murphy discusses CAR T-cell cancer therapy and his work with Caring Cross, CIRM and UC Davis researchers to find novel cures to leukemia and lymphoma.
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December 14, 2022UC Davis Alpha Stem Cell Clinic receives $8 million from California’s stem cell agency
CIRM awarded UC Davis’ Alpha Stem Cell Clinic an $8 million grant renewal to expand its successful clinical trials operation and advance toward onsite manufacturing of therapies.
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October 11, 2022CuRe trial gives hope to new mom
Michelle and Jeff were excited to build their new family together, but when she received the distressing news that her developing baby was diagnosed with spina bifida, she looked for the best treatment. She was referred to the CuRe trial.
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October 06, 2022
World’s first stem cell treatment for spina bifida delivered during fetal surgery
Three babies have been born after receiving the world’s first spina bifida treatment combining surgery with stem cells. This was made possible by a landmark clinical trial at UC Davis Health known formally as the “CuRe Trial: Cellular Therapy for In Utero Repair of Myelomeningocele.”
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May 26, 2022UC Davis wins $3 million CIRM grant to develop smart vascular graft for kidney patients
Professor Aijun Wang won $3 million grant from California Institute for Regenerative Medicine to develop a smart durable vascular device for hemodialysis patients treated for kidney failure. The device uses a unique molecule to help prevent synthetic vascular graft failure, a common problem for patients undergoing hemodialysis.
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March 29, 2022$4 million research program seeks therapy for rare genetic condition ADNP syndrome
The UC Davis MIND Institute is launching a $4 million research program aimed at finding transformative therapies for ADNP syndrome, a rare genetic condition. A group of interdisciplinary researchers will evaluate multiple gene therapies for possible use.
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August 26, 2021California’s stem cell agency funds research into Angelman syndrome and bioprint pacemaker
Professors David Segal and Deborah Lieu have received Discovery Stage Research Projects awards from the California Institute for Regenerative Medicine (CIRM). The grants will fund cell gene therapy for Angelman syndrome and building the first biopacemaker
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