Kevin C. Kent Lloyd, D.V.M., Ph.D. for UC Davis Health

Kevin C. Kent Lloyd, D.V.M., Ph.D.

Kevin C. Kent Lloyd, D.V.M., Ph.D.

Distinguished Professor, Department of Surgery

Director, UC Davis Mouse Biology Program

Reviews

Specialties

Genetics

Cancer

Department

Surgery

Locations and Contact

Additional Numbers

Phone

530-754-6687

Research/Academic Interests

Dr. Lloyd's research focuses on understanding the genetic basis for both rare and common diseases.  He studies gene function in health and disease using in vivo models created using multiple strategies, including gene targeting and genome editing.

Division

General Surgery

Center/Program Affiliation

UC Davis Comprehensive Cancer Center

Undergraduate School

B.S., Biology/Biochemistry, UC San Diego, San Diego CA 1979

Medical School

D.V.M., UC Davis, Davis CA 1983

Other School

Ph.D., Physiology, UC Los Angeles, Los Angeles CA 1992

Internship

Medicine/Surgery, University of Pennsylvania, Kennet Square PA 1983-1984

Residency

Surgery, UC Davis, Davis CA 1984-1987

Fellowship

Physiology, UCLA, Los Angeles CA 1987-1991

Dean’s Excellence in Research Award, 2017

Lawrence Berkeley Seminar, 2017

American Association for the Advancement of Science Fellow, 2013

Glaxo Research Institute Fellow's Award, 1991

Harwell Prize in Pharmacology, 1983

Higgins K, Moore BA, Berberovic Z, Adissu HA, Eskandarian M, Flenniken AM, Shao A, Imai DM, Clary D, Lanoue L, Newbigging S, Nutter LMJ, Adams DJ, Bosch F, Braun RE, Brown SDM, Dickinson ME, Dobbie M, Flicek P, Gao X, Galande S, Grobler A, Heaney JD, Herault Y, de Angelis MH, Chin HG, Mammano F, Qin C, Shiroishi T, Sedlacek R, Seong JK, Xu Y; IMPC Consortium; Lloyd KCK, McKerlie C, Moshiri A. Analysis of genome-wide knockout mouse database identifies candidate ciliopathy genes. Sci Rep. 2022 Dec 1;12(1):20791. doi:10.1038/s41598-022-19710-7. PMID:36456625.

Waight E, Zhang C, Mathews S, Kevadiya BD, Lloyd KCK, Gendelman HE, Gorantla S, Poluektova LY, Dash PK. Animal models for studies of HIV-1 brain reservoirs. J Leukoc Biol. 2022 Nov;112(5):1285-1295. doi:10.1002/JLB.5VMR0322-161R. Epub 2022 Aug 31. PMID:36044375.

Cacheiro P, Westerberg CH, Mager J, Dickinson ME, Nutter LMJ, Muñoz-Fuentes V, Hsu CW, Van den Veyver IB, Flenniken AM, McKerlie C, Murray SA, Teboul L, Heaney JD, Lloyd KCK, Lanoue L, Braun RE, White JK, Creighton AK, Laurin V, Guo R, Qu D, Wells S, Cleak J, Bunton-Stasyshyn R, Stewart M, Harrisson J, Mason J, Haseli Mashhadi H, Parkinson H, Mallon AM; International Mouse Phenotyping Consortium; Genomics England Research Consortium; Smedley D. Mendelian gene identification through mouse embryo viability screening. Genome Med. 2022 Oct 13;14(1):119. doi:10.1186/s13073-022-01118-7. PMID:36229886.

Cheng KC, Burdine RD, Dickinson ME, Ekker SC, Lin AY, Lloyd KCK, Lutz CM, MacRae CA, Morrison JH, O'Connor DH, Postlethwait JH, Rogers CD, Sanchez S, Simpson JH, Talbot WS, Wallace DC, Weimer JM, Bellen HJ. Promoting validation and cross-phylogenetic integration in model organism research. Dis Model Mech. 2022 Sep 1;15(9):dmm049600. doi:10.1242/dmm.049600. Epub 2022 Sep 20. PMID:36125045.

Muratoglu SC, Charette MF, Galis ZS, Greenstein AS, Daugherty A, Joutel A, Kozel BA, Wilcock DM, Collins EC, Sorond FA, Howell GR, Hyacinth HI, Lloyd KKC, Stenmark KR, Boehm M, Kahn ML, Corriveau R, Wells S, Bussey TJ, Sukoff Rizzo SJ, Iruela-Arispe ML. Perspectives on Cognitive Phenotypes and Models of Vascular Disease. Arterioscler Thromb Vasc Biol. 2022 Jul;42(7):831-838. doi:10.1161/ATVBAHA.122.317395. Epub 2022 May 5. PMID:35510549.

Shankar SP, Grimsrud K, Lanoue L, Egense A, Willis B, Hörberg J, AlAbdi L, Mayer K, Ütkür K, Monaghan KG, Krier J, Stoler J, Alnemer M, Shankar PR, Schaffrath R, Alkuraya FS, Brinkmann U, Eriksson LA, Lloyd K, Rauen KA; Undiagnosed Diseases Network. A novel DPH5-related diphthamide-deficiency syndrome causing embryonic lethality or profound neurodevelopmental disorder. Genet Med. 2022 Jul;24(7):1567-1582. doi:10.1016/j.gim.2022.03.014. Epub 2022 Apr 28. Erratum in: Genet Med. 2022 Oct;24(10):2207. PMID:35482014.

Shao A, Lopez AJ, Chen J, Tham A, Javier S, Quiroz A, Frick S, Levine EM, Lloyd KCK, Leonard BC, Murphy CJ, Glaser TM, Moshiri A. Arap1 loss causes retinal pigment epithelium phagocytic dysfunction and subsequent photoreceptor death. Dis Model Mech. 2022 Jul 1;15(7):dmm049343. doi:10.1242/dmm.049343. Epub 2022 Jul 25. PMID:35758026.

Jacobsen JOB, Baudis M, Baynam GS, Beckmann JS, Beltran S, Buske OJ, Callahan TJ, Chute CG, Courtot M, Danis D, Elemento O, Essenwanger A, Freimuth RR, Gargano MA, Groza T, Hamosh A, Harris NL, Kaliyaperumal R, Lloyd KCK, Khalifa A, Krawitz PM, Köhler S, Laraway BJ, Lehväslaiho H, Matalonga L, McMurry JA, Metke-Jimenez A, Mungall CJ, Munoz-Torres MC, Ogishima S, Papakonstantinou A, Piscia D, Pontikos N, Queralt-Rosinach N, Roos M, Sass J, Schofield PN, Seelow D, Siapos A, Smedley D, Smith LD, Steinhaus R, Sundaramurthi JC, Swietlik EM, Thun S, Vasilevsky NA, Wagner AH, Warner JL, Weiland C; GAGH Phenopacket Modeling Consortium; Haendel MA, Robinson PN. The GA4GH Phenopacket schema defines a computable representation of clinical data. Nat Biotechnol. 2022 Jun;40(6):817-820. doi:10.1038/s41587-022-01357-4. PMID:35705716.

Spielmann N, Miller G, Oprea TI et al. Extensive identification of genes involved in congenital and structural heart disorders and cardiomyopathy. Nat Cardiovasc Res. 2022 Feb 17;1:157–173. doi:10.1038/s44161-022-00018-8.