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    Clinical Trials: New Developments in Dermatology

The UC Davis Department of Dermatology has several ongoing clinical trials. Click below to learn more.

Use of embrace device after cutaneous wound closure: a randomized evaluator blinded split wound comparative effectiveness trial

Primary Investigator: Daniel Eisen, MD
Contact: Angela Calaguas, (916) 551-2636
Participant Criteria: Current or past patient of primary investigator

 

Aesthetic outcome of complex linear closure vs second intention healing for cutaneous surgical procedures performed below the knee: a randomized, blind control trial

Primary Investigator: Daniel Eisen, MD
Contact: Angela Calaguas, (916) 551-2636
Participant Criteria: Current or past patient of primary investigator

 

Aesthetic outcome of electrodesiccation and curettage vs excision with complex linear closure for low risk lesions on the trunk and extremities: a randomized, blind control trial

Primary Investigator: Daniel Eisen, MD
Contact: Angela Calaguas, (916) 551-2636
Participant Criteria: Current or past patient of primary investigator

 

Antibiotic adherence practices in dermatologic surgery: a multicenter prospective cohort study

Primary Investigator: Daniel Eisen, MD
Contact: Angela Calaguas, (916) 551-2636
Participant Criteria: Current or past patient of primary investigator

Influence of Sun Protection on the Aesthetic Outcomes Following Linear Repair of Cutaneous Surgical Defects, a Randomized Split-Wound Study

Primary Investigator: Daniel Eisen, MD
Contact: Angela Calaguas, (916) 551-2636
Participant Criteria: Current or past patient of primary investigator

Satisfaction of Closing defects After facial skin cancer Resection (SCAR) Study

Primary Investigator: Daniel Eisen, MD
Contact: Angela Calaguas, (916) 551-2636
Participant Criteria: Current or past patient of primary investigator

No current active trials.

Registry for the Study of Atopic Dermatitis Morphologic Phenotypes

Indication: Atopic Dermatitis in Children
Primary Investigator: Smita Awasthi, MD
Contact: Angela Calaguas, (916) 551-2636
Participant Criteria:

      • Pediatric patient < 17.7 years of age at time of enrollment
      • Clinical diagnosis of atopic dermatitis

Genetic aberrations driving cutaneous disease

Indication: Genetics and cutaneous disease
Primary Investigator: Maija Kiuru, MD
Contact: Angela Calaguas, (916) 551-2636
Participant Criteria:

      • Subjects with active cutaneous, hair or nail disease (*this is something that must be confirmed by a dermatologist. We get those subjects from UCD dermatologists)
      • 18 years of age or older

A pilot study of transcriptional mechanisms underlying repigmentation of graying hair following cranial radiation treatment

Primary Investigator: Maija Kiuru, MD
Contact: Angela Calaguas, (916) 551-2636
Participant Criteria:

      • 18 years of age or older
      • Those who will receive or have received cranial radiation
      • Partially or completely gray hair
      • Willing to obtain biopsies of scalp

No current active trials.

Effect of pre-operative consultation on patient anxiety and satisfaction following first-time Mohs micrographic surgery


Primary Investigator: Daniel Eisen, MD
Contact: Angela Calaguas, (916) 551-2636
Participant Criteria: Current or past patient of primary investigator

Genetic basis of melanocytic nevi

Primary Investigator: Maija Kiuru, MD
Contact: Angela Calaguas, (916) 551-2636
Participant Criteria:

      • Subjects with melanocytic nevi
      • 18 years of age or older

A Phase 1, Open-Label, Safety and Dosing Study of Autologous Desmoglein 3 Chimeric Autoantibody Receptor T Cells (DSG3-CAART) in Subjects with Active, Anti- DSG3, Mucosal-dominant Pemphigus Vulgaris

Primary Investigator: Emanual Maverakis, MD
Contact: Lauren Downing, (916) 551-2635
Participant Criteria:

      • DSG1 neg, DSG3 pos mucosal-dominant pemphigus vulgaris confirmed by prior ELISA
      • failure of at least one standard therapy

A Phase 2B, Randomized, multicenter, double-blind, placebo-controlled, multiple-dose study to evaluate the efficacy, safety, and tolerability of NDI-034858 In subjects with moderate to severe plaque psoriasis.

Primary Investigator: Emanual Maverakis, MD
Contact: Jordan Nava, (916) 551-2633
Participant Criteria:

      • At least 18 years old; chronic plaque psoriasis at least 6 months prior; greater than 10% BSA

Evaluation of AMG 714 for Vitiligo: A Phase 2a Randomized Double Blind Placebo Controlled Trial

Primary Investigator: Victor Huang, MD
Contact: Angela Calaguas, (916) 551-2636
Participant Criteria:

      • Age: Adults 18-75
      • F-VASI greater than or equal to 0.25
      • T-VASI greater than or equal to 3

A Prospective Multi-Arm Blinded Evaluator Within-Subject Randomized Controlled Clinical Study to Investigate the Safety and Effectiveness of RECELL for Repigmentation of Stable Vitiligo Lesions

Primary Investigator: Victor Huang, MD
Contact: Angela Calaguas, (916) 551-2636
Participant Criteria:

      • Focal, segmental or generalized (i.e., nonsegmental) stable vitiligo
      • Patient must have two study areas available for treatment that are between 16cm2 and 456cm2

Dysbiosis of the Gut Microbiome in Individuals with Type 2 Diabetes, Psoriasis, Essential Hypertension, or Hidradenitis Suppurativa and Correlation with the Blood Lipidome Profile

Indication: Gut Dysbiosis
Primary Investigator: Raja Sivamani, MD
Contact: Angela Calaguas, (916) 551-2636
Participant Criteria:

      • Patients diagnosed with psoriasis
      • Patients diagnosed with hidradenitis suppurativa with a Hurley score of at least 2
      • Patients diagnosed with type 2 diabetes
      • Patients diagnosed with essential hypertension
      • 18 years of age or older

Prospective Evaluation of Topical Almond Oil vs Hydroquinone on the Appearance of Facial Pigmentation and the Stability of the Microbiome

Indication: Skin pigmentation
Primary Investigator: Raja Sivamani, MD
Contact: Angela Calaguas, (916) 551-2636
Participant Criteria:

      • Pre-menopausal women of Fitzpatrick skin types 3 to 6 

The Effect of Topical Almond Oil vs. Topical Retinol on The Appearance of Facial Wrinkles

Indication: Facial wrinkles
Primary Investigator: Raja Sivamani, MD
Contact: Angela Calaguas, (916) 551-2636
Participant Criteria:

      • Post-menopausal women of Fitzpatrick skin types 1 and 2 

 

A pilot study of transcriptional mechanisms underlying repigmentation of graying hair following cranial radiation treatment

Primary Investigator: Maija Kiuru, MD
Contact: Angela Calaguas, (916) 551-2636
Participant Criteria:

      • 18 years of age or older
      • Those who will receive or have received cranial radiation
      • Partially or completely gray hair
      • Willing to obtain biopsies of scalp

 

 

Hidradenitis suppurativa:

 A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Imsidolimab (ANB019) in the Treatment of Subjects with Hidradenitis Suppurativa

Primary Investigator: Emanual Maverakis, MD
Contact: Monica Tran, (916) 551-2634

Psoriasis:

A Phase 2b, Randomized, Multicenter, Double-Blind, Placebo-Controlled, Multiple-Dose Study to Evaluate the Efficacy, Safety, and Tolerability of NDI-034858 in Subjects with Moderate to Severe Plaque Psoriasis

Primary Investigator: Emanual Maverakis, MD
Contact: Monica Tran, (916) 551-2634