Nanette Cunningham Joyce, D.O., M.A.S. for UC Davis Health

Nanette Cunningham Joyce, D.O., M.A.S.

Associate Professor, Department of Physical Medicine and Rehabilitation

To see if Nanette Cunningham Joyce is accepting new patients, or for assistance finding a UC Davis doctor, please call 800-2-UCDAVIS (800-282-3284).



Physical Medicine and Rehabilitation

Electrodiagnostic Medicine

Neuromuscular Medicine

Locations and Contact

Lawrence J. Ellison Ambulatory Care Center

Physical Medicine & Rehabilitation
4860 Y St.
Sacramento, CA 95817

Get Directions

Phone: 916-734-7041

Additional Numbers

Clinic Fax


Philosophy of Care

I believe in providing patient/family centered care for those with complex medical needs caused by neuromuscular disease. I work with expert allied professionals in a team-based multidisciplinary clinic to provide the highest quality care. Our goal is to offer interventions that maximize independence, improve quality of life, and treat the underlying disease process to prolong life.

Clinical Interests

Dr. Joyce is a physiatrist who is fellowship-trained in neuromuscular medicine and electrodiagnosis. She has special clinical interest and expertise in treating patients with amyotrophic lateral sclerosis, spinal muscular atrophy, and hereditary muscular dystrophies.

Research/Academic Interests

Dr. Joyce's research focuses on the translation of disease-modifying therapeutics targeting the rare disease neuromuscular patient population. She participates in large international and national research groups studying these diseases; defining natural history and developing outcome measures in order quantify change with clinical trial interventions. 


Physical Medicine and Rehabilitation

Undergraduate School

B.A., Liberal Studies, University of the Pacific, Stockton CA 1982

Medical School

D.O., Touro University College of Osteopathic Medicine, Vallejo CA 2004

Other School

M.A.S., Clinical Research, UC Davis, Davis CA 2012


Physical Medicine and Rehabiliation Linked Osteopathic Rotating Internship, Michigan State University College of Osteopathic Medicine/Ingham Regional Medical Center, Lansing MI 2004-2005


Physical Medicine and Rehabiliation, Michigan State University College of Osteopathic of Osteopathic Medicine, East Lansing MI 2005-2008


Physical Medicine and Rehabilitation/Research Neuromuscular Medicine, UC Davis School of Medicine, Sacramento CA 2009-2011


Physical Medicine and Rehabilitation/Clinical Neuromuscular Medicine, UC Davis School of Medicine, Sacramento CA 2008-2009

Emmy Award Recipient; Beyond the Ice-Bucket Challenge - Battling ALS, 2019

David D. Kilmer Resident Teaching Award, 2017

Herrenhausen Conference: International Ethics Symposium Grantee, 2016

Dean’s Team Award for Clinical Care: Neuromuscular Medicine Clinic, 2014

Dean’s Team Award for Clinical Care: Multidisciplinary ALS Clinic, 2012

Guglieri M, Bushby K, McDermott M, Hart KA, Tawil R, Martens WB, Herr B, McColl E, Wilkinson J, Kirschner J, King WM, Eagle M, Brown M, Willis T, Straub V, Childs A, Ciafaloni E, Shieh PB, Spinty S, Maggi L, Baranello G, Butterfield RJ, Horrocks I A, MRCPUK, Roper H, Alhaswani Z, Flanigan KM, Kuntz N, Manzur A, Darras BT, Kang P, Morrison L, Krzesniak-Swinarska M, Mah JK, Mongini TE, Ricci F, von der Hagen M, Finkel RS, O’Reardon K, Wicklund M, Kumar A, McDonald CM, Han J, Joyce N, Henricson EK, Schara-Schmidt U, Gangfuss A, Wilichowski E, Barohn RJ, Statland JM, Campbell C, Vita G, Vita GL, Howard JF, Hughes I, McMillan HJ, Pegoraro E, Bello L, Burnette WB, Thangarajh M, Chang T, Griggs RC, the Muscle Study Group; Treat-NMD. Comparative Effectiveness of Corticosteroid Regimens for Duchenne Muscular Dystrophy: A Randomized Controlled Trial. JAMA in press.

McDonald CM, Marbán E, Hendrix S, Hogan N, Ruckdeschel Smith R, Eagle M, Finkel RS, Tian 7, Janas J, Harmelink MW, VaradhacharyAS, Taylor1 M, Hor KN, Mayer OH, Henricson EK, Furlong P, Ascheim DD, Rogy S, Williams P, Marbán L, and the HOPE-2 Investigators. Human Allogeneic Cardiosphere-derived Cells in Late-stage Duchenne Muscular Dystrophy. The Lancet. 2022 Mar 12;399(10329):p1049-1058. doi:10.1016/S0140-6736(22)00012-5.

Lingineni K, Aggarwal V, Morales JF, Conrado DJ, Corey D, Vong C, Burton J, Larkindale J, Romero K, Schmidt S, Kim S; Cooperative International Neuromuscular Research Group investigators and Duchenne Regulatory Science Consortium members. Development of a model-based clinical trial simulation platform to optimize the design of clinical trials for Duchenne muscular dystrophy. CPT Pharmacometrics Syst Pharmacol. 2021 Dec 8. doi:10.1002/psp4.12753. Epub ahead of print. PMID:34877803.

Landfeldt E, Iff J, Henricson E; Cooperative International Neuromuscular Research Group Investigators. Rasch Analysis of the Pediatric Quality of Life Inventory 4.0 Generic Core Scales Administered to Patients With Duchenne Muscular Dystrophy. Value Health. 2021 Oct;24(10):1490-1498. doi:10.1016/j.jval.2021.05.016. Epub 2021 Sep 9. PMID:34593173.

Amato AA, Hanna MG, Machado PM, Badrising UA, Chinoy H, Benveniste O, Karanam AK, Wu M, Tankó LB, Schubert-Tennigkeit AA, Papanicolaou DA, Lloyd TE, Needham M, Liang C, Reardon KA, de Visser M, Ascherman DP, Barohn RJ, Dimachkie MM, Miller JAL, Kissel JT, Oskarsson B, Joyce NC, Van den Bergh P, Baets J, De Bleecker JL, Karam C, David WS, Mirabella M, Nations SP, Jung HH, Pegoraro E, Maggi L, Rodolico C, Filosto M, Shaibani AI, Sivakumar K, Goyal NA, Mori-Yoshimura M, Yamashita S, Suzuki N, Aoki M, Katsuno M, Morihata H, Murata K, Nodera H, Nishino I, Romano CD, Williams VSL, Vissing J, Zhang Auberson L; RESILIENT Study Extension Group. Efficacy and Safety of Bimagrumab in Sporadic Inclusion Body Myositis: Long-term Extension of RESILIENT. Neurology. 2021 Mar 23;96(12):e1595-e1607. doi:10.1212/WNL.0000000000011626. Epub 2021 Feb 17. PMID:33597289.

McDonald CM, Ramirez-Sanchez I, Oskarsson B, Aguilar C, Nicorici A, Joyce N, Reddy D, Wagner A, Goude E, Abresch RT, Villarreal F, Ceballos G, Perkins G, Dugar S, Schreiner G, Henricson EK. (-)-epicatechin induces mitochondrial biogenesis and muscle regeneration in adults with Becker muscular dystrophy. Muscle Nerve. 2021 Feb;63(2):239-249. doi:10.1002/mus.27108. Epub 2020 Dec 16. PMID:33125736.

Goemans N, Signorovitch J, Sajeev G, Yao Z, Gordish-Dressman H, McDonald CM, Vandenborne K, Miller D, Ward SJ, Mercuri E; investigators from PRO-DMD-01 Study, CINRG DNHS, ImagingDMD, and the DMD Italian Group. Suitability of external controls for drug evaluation in Duchenne muscular dystrophy. Neurology. 2020 Sep 8;95(10):e1381-e1391. doi:10.1212/WNL.0000000000010170. Epub 2020 Jul 1. PMID:32611643.

Spitali P, Zaharieva I, Bohringer S, Hiller M, Chaouch A, Roos A, Scotton C, Claustres M, Bello L, McDonald CM, Hoffman EP; CINRG Investigators, Koeks Z, Eka Suchiman H, Cirak S, Scoto M, Reza M, 't Hoen PAC, Niks EH, Tuffery-Giraud S, Lochmüller H, Ferlini A, Muntoni F, Aartsma-Rus A. TCTEX1D1 is a genetic modifier of disease progression in Duchenne muscular dystrophy. Eur J Hum Genet. 2020 Jan 2;28:815-825. doi:10.1038/s41431-019-0563-6.

Mitsumoto H, Chiuzan C, Gilmore M, Zhang Y, Simmons Z, Paganoni S, Kisanuki YY, Zinman L, Jawdat O, Sorenson E, Floeter MK, Pioro EP, Fernandes Filho JAM, Heitzman D, Fournier CN, Oskarsson B, Heiman-Patterson T, Maragakis N, Joyce N, Hayat G, Nations S, Scelsa S, Walk D, Elman L, Hupf J, McHale B; PLSFRS study group. Primary lateral sclerosis (PLS) functional rating scale: PLS-specific clinimetric scale. Muscle Nerve. 2020 Feb;61(2):163-172. doi:10.1002/mus.26765. Epub 2019 Dec 13. PMID:31758557.

Shefner JM, Cudkowicz ME, Hardiman O, Cockcroft BM, Lee JH, Malik FI, Meng L, Rudnicki SA, Wolff AA, Andrews JA; VITALITY-ALS Study Group. A phase III trial of tirasemtiv as a potential treatment for amyotrophic lateral sclerosis. Amyotroph Lateral Scler Frontotemporal Degener. 2019;0(0):1-11. doi:10.1080/21678421.2019.1612922. Erratum in: Amyotroph Lateral Scler Frontotemporal Degener. 2019 Jul 14;:1. PMID:31081694.