Research in Trauma, Acute Care Surgery and Surgical Critical Care
Faculty members in the Division of Trauma, Acute Care Surgery, and Surgical Critical Care are involved in clinical, basic science, surgical education, injury prevention, and translational research spanning the entire breadth of the discipline of trauma and critical care.
Double-Blind, Placebo-Controlled Study Of AB103 — prospective randomized trial that compares study drug to placebo in patients with necrotizing soft tissue infections
Sigh Ventilation to Increase Ventilator-Free Days in Victims of Trauma at Risk for Acute Respiratory Distress Syndrome — This study aims to determine if adding a sigh-type of breath to a ventilator reduces chances of developing more serious lung problems
Vascular Trauma Registry — prospective multi-institutional trial that aims to capture key elements of vascular trauma presentation, diagnosis, management, and outcomes
Effects of Local Anesthetics for Acute Pain in Hip and Femur Fractures — a prospective randomized trial that evaluates the effectiveness of long acting liposomal bupivacaine as an analgesia in injured trauma patients
Complications of Vascular and Microvascular Thrombosis in Acute Trauma — a prospective study that determines whether certain protein levels in blood predict complications such as organ failure
Ventilator Associated Pneumonia in ICU Patients — a retrospective chart review that determines if ventilator associated pneumonia is correlated to time in operating room
Policy Relevant US Trauma Care System — aims to conduct a pragmatic randomized effectiveness trial of a collaborative care intervention targeting posttraumatic stress disorder and comorbid conditions after acute care surgery hospitalization
Characterization and Modulation of Systemic Cellular Injury in severe trauma patients
Phase 2 Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study with Reltecimod — This trial evaluates the safety and efficacy of Reltecimod in patients with sepsis-associated acute kidney injury
Trauma Vascular Surgery Toolbox — evaluation and development of a skill set & training course for the combat surgeon with respect to vascular surgery
Pediatric Resuscitative Thoracotomy in Trauma — a multicenter retrospective study that evaluates the safety and efficacy of resuscitative thoracotomy
Blunt Thoracic Aortic Injury — a multi-institutional prospective study that examines diagnosis, management and outcomes following blunt thoracic aortic injury
Implementation of a Hospital-Based Violence Recidivism Prevention Program — The proposed research evaluates the efficacy of a successful hospital-based violence intervention program and determines what needs are present in the community
Pain in Trauma Patients — a retrospective data review that determines risk factors associated with long-term opioid use
Traumatic Brain Injury — a randomized trial that determines the transfusion threshold for anemia in the setting of acute traumatic brain injury
Splenic Injury — a prospective randomized trial that investigates the antibody response to pneumococcal vaccine in splenic injury
Trauma Patients with Alcohol Use Disorders — prospective randomized trial that evaluates brief interventions for alcohol use among injured patients
John T. Anderson, M.D.
Christine S. Cocanour, M.D
Joseph M. Galante, M.D.
Ho H. Phan, M.D.
Edgardo S. Salcedo, M.D.
David V. Shatz, M.D.
Garth H. Utter, M.D.
David H. Wisner, M.D.
Scott A. Zakaluzny, M.D.
Ian E. Brown, M.D.
Gregory Jurkovich, M.D.
Rachel A. Hight, M.D.
David Leshikar, M.D.
A. Francios Trappey, M.D.