Barton L. Wise, M.D., M.Sc. for UC Davis Health

Barton L. Wise, M.D., M.Sc.

Associate Vice Chair for Clinical Research, Department of Orthopaedic Surgery

Professor, Department of Orthopaedic Surgery

Professor in Residence, Department of Internal Medicine

To see if Barton L. Wise is accepting new patients, or for assistance finding a UC Davis doctor, please call 800-2-UCDAVIS (800-282-3284).




Clinical Research

Rheumatology, Allergy and Clinical Immunology

Locations and Contact

Lawrence J. Ellison Ambulatory Care Center

Lawrence J. Ellison Ambulatory Care Center
4860 Y St.
Sacramento, CA 95817

Get Directions

Additional Numbers

Clinic Phone


Physician Referrals

800-4-UCDAVIS (800-482-3284)

Philosophy of Care

I will work with you to achieve your goals in life and support you towards them, through medical diagnosis, treatment and in other ways as appropriate. I try to create a welcoming environment where you will know that your concerns will be addressed.

Clinical Interests

Dr. Wise diagnoses and treats a range of rheumatologic conditions, including rheumatoid arthritis, systemic lupus erythematosus, osteoarthritis and others. As Associate Vice Chair for Clinical Research for the Department of Orthopaedic Surgery, he also oversees clinical trials related to arthritis and treatments for it.

Research/Academic Interests

Dr. Wise is a clinical and basic researcher with research interests in osteoarthritis and other forms of arthritis, sex differences, clinical trials, mindfulness and compassion, and pain.


Orthopaedic Surgery
Rheumatology, Allergy and Clinical Immunology

Undergraduate School

B.A., Geology/Anthropology, Brown University, Providence RI 1989

Medical School

M.D., Boston University School of Medicine, Boston MA 2002

Other School

M.Sc., Epidemiology, Boston University School of Public Health, Boston MA 2009


Internal Medicine, Brown University/Rhode Island and Miriam Hospitals, Providence RI 2002-2003


Internal Medicine, Brown University/Rhode Island and Miriam Hospitals, Providence RI 2003-2005


Rheumatology, Boston University/Boston University Medical Center, Boston MA 2005-2008

UC Davis Dean’s Award for Excellence in Mentoring at Early to Mid-Career Level, 2016

UC Davis Dean’s Team Award for Excellence in Research, 2012

John A. Hartford, American Federation for Aging Research Scholar, 1999

Liu L, Jia J, Jiang M, Liu X, Dai C, Wise BL, Lane NE, Yao W. High susceptibility to collagen-induced arthritis in mice with progesterone receptors selectively inhibited in osteoprogenitor cells. Arthritis Res Ther. 2020 Jul 2;22(1):165. doi:10.1186/s13075-020-02242-8. PMID:32616012.

Wise BL, Niu J, Zhang Y, Liu F, Pang J, Lynch JA, Lane NE. Patterns of Change Over Time in Knee Bone Shape Are Associated with Sex. Clin Orthop Relat Res. 2020 Jul;478(7):1491-1502. doi:10.1097/CORR.0000000000001219. PMID:32187098.

Kolasinski SL, Neogi T, Hochberg MC, Oatis C, Guyatt G, Block J, Callahan L, Copenhaver C, Dodge C, Felson D, Gellar K, Harvey WF, Hawker G, Herzig E, Kwoh CK, Nelson AE, Samuels J, Scanzello C, White D, Wise B, Altman RD, DiRenzo D, Fontanarosa J, Giradi G, Ishimori M, Misra D, Shah AA, Shmagel AK, Thoma LM, Turgunbaev M, Turner AS, Reston J. 2019 American College of Rheumatology/Arthritis Foundation Guideline for the Management of Osteoarthritis of the Hand, Hip, and Knee. Arthritis Care Res (Hoboken). 2020 Feb;72(2):149-162. doi:10.1002/acr.24131. Epub 2020 Jan 6. Erratum in: Arthritis Care Res (Hoboken). 2021 May;73(5):764. PMID:31908149.

Wise BL, Niu J, Zhang Y, Liu F, Pang J, Lynch JA, Lane NE. Bone shape mediates the relationship between sex and incident knee osteoarthritis. BMC Musculoskelet Disord. 2018 Sep 12;19(1):331. doi:10.1186/s12891-018-2251-z. PMID:30208910.

Hu B, Skou ST, Wise BL, Williams GN, Nevitt MC, Segal NA. Lower Quadriceps Rate of Force Development Is Associated With Worsening Physical Function in Adults With or at Risk for Knee Osteoarthritis: 36-Month Follow-Up Data From the Osteoarthritis Initiative. Arch Phys Med Rehabil. 2018 Jul;99(7):1352-1359. doi:10.1016/j.apmr.2017.12.027. Epub 2018 Jan 31. PMID:29408538.

Wise BL, Niu J, Guermazi A, Liu F, Heilmeier U, Ku E, Lynch JA, Zhang Y, Felson DT, Kwoh CK, Lane NE. Magnetic resonance imaging lesions are more severe and cartilage T2 relaxation time measurements are higher in isolated lateral compartment radiographic knee osteoarthritis than in isolated medial compartment disease - data from the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2017 Jan;25(1):85-93. doi:10.1016/j.joca.2016.08.002. Epub 2016 Aug 15. PMID:27539891.

Wise BL, Liu F, Kritikos L, Lynch JA, Parimi N, Zhang Y, Lane NE. The association of distal femur and proximal tibia shape with sex: The Osteoarthritis Initiative. Semin Arthritis Rheum. 2016 Aug;46(1):20-6. doi:10.1016/j.semarthrit.2016.02.006. Epub 2016 Mar 3. PMID:27039962.

Wise BL, Niu J, Felson DT, Hietpas J, Sadosky A, Torner J, Lewis CE, Nevitt M. Functional Impairment Is a Risk Factor for Knee Replacement in the Multicenter Osteoarthritis Study. Clin Orthop Relat Res. 2015 Aug;473(8):2505-13. doi:10.1007/s11999-015-4211-3. PMID:25754756.

Chaudhari AJ, Leahy RM, Wise BL, Lane NE, Badawi RD, Joshi AA. Global point signature for shape analysis of carpal bones. Phys Med Biol. 2014 Feb 21;59(4):961-73. doi:10.1088/0031-9155/59/4/961. Epub 2014 Feb 7. PMID:24503490.

Lane NE, Parimi N, Lui LY, Wise BL, Yao W, Lay YA, Cawthon PM, Orwoll E; Osteoporotic Fractures in Men Study Group. Association of serum uric acid and incident nonspine fractures in elderly men: the Osteoporotic Fractures in Men (MrOS) study. J Bone Miner Res. 2014 Jul;29(7):1701-7. doi:10.1002/jbmr.2164. PMID:24347506.