Shiro Urayama, M.D.

Shiro Urayama, M.D.




  • Health Sciences Clinical Professor


To see if Shiro Urayama is accepting new patients, or for assistance finding a UC Davis doctor, please call 800-2-UCDAVIS (800-282-3284).

UC Davis Midtown Ambulatory Care Center

3160 Folsom Blvd, Suite 3500
Sacramento, CA 95816
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Primary Phone:

UC Davis Medical Center

2315 Stockton Blvd., Suite 3016
Sacramento, CA 95817
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Primary Phone:

Additional Phone Numbers

Clinic Phone: 916-851-1480
Clinic Fax: 916-451-3039
Physician Referrals: 800-4-UCDAVIS (800-482-3284)

Philosophy of Care

Dr. Shiro Urayama is focused on patient-centered clinical care and researching application of technology for developing best care for gastrointestinal diseases in the patient.

Clinical Interests

Dr. Shiro Urayama specializes in advanced endoscopy including EUS (Endoscopic Ultrasound), ERCP (Endoscopic Retrograde Cholangiopancreatography) and various intra- and extra-luminal interventions including endoscopic mucosal resections/submucosal dissections, ablative procedures, and placement of luminal prosthesis for luminal and periluminal diseases.

He has published studies on the endoscopic diagnostic and therapeutic intervention approaches in GI cancers and investigations on novel detection modalities of precancerous lesions. Specifically his research involves the application of endoscopic ultrasound and early diagnosis of gastrointestinal cancers.

Research/Academic Interests

Dr. Urayama's research forcuses on diagnostics and endoscopic therapeutics for gastrointestinal malignancies in GI tract and pancreas. He has keen interest in incorporating developing technology and translational research for development of early cancer detection schemes and therapeutics.


Gastroenterology and Hepatology

Center/Program Affiliation

UC Davis Comprehensive Cancer Center
UC Davis Medical Group


M.D., Medical College of Wisconsin, Milwaukee WI 1992

B.S. with Honors, University of Washington, Seattle WA 1988

Internship: Internal Medicine, Virginia Mason Medical Center, Seattle WA 1992-1993


Internal Medicine, Virginia Mason Medical Center, Seattle WA 1993-1995


Endoscopic Ultrasonography (EUS), Columbia University, Columbia Presbyterian Medical Center, New York City NY 1999

Gastroenterology, University of Chicago, Chicago IL 1995-1999

Board Certifications

American Board of Internal Medicine,

American Board of Internal Medicine, Gastroenterology and Hepatology,

Professional Memberships

American Association for Cancer Research (AACR)

American College of Physicians

American Gastroenterological Association

American Society of Gastrointestinal Endoscopy

Honors and Awards

Marquis Who�s Who in America: Albert Nelson Marquis Lifetime Achievement Award, 2019, 2020

Sacramento Magazine, Best Doctor, 2019

UC Davis New Innovation/Collaboratory Research Award, 2010

UC Davis Health System Research Award, 2004

UC Cancer Research Coordinating Committee Research Award, 2003

Select Recent Publications

Eskandari A, Koo P, Bang H, Gui D, Urayama S. Comparison of endoscopic ultrasound biopsy needles for endoscopic ultrasound-guided liver biopsy. Clinical Endoscopy. 2019 Jul; 52(4):347–352. Published online 2019 Jul 10. doi:10.5946/ce.2019.005

Wani S, Urayama S, et al. Setting minimum standards for training in EUS and ERCP: results from a prospective multicenter study evaluating learning curves and competence among advanced endoscopy trainees. Gastrointest Endosc. 2019 Jun;89(6):1160-1168.e9. doi:10.1016/j.gie.2019.01.030. Epub 2019 Feb 7.

Wani S, Urayama S, et al. Competence in Endoscopic ultrasound and endoscopic retrograde chlangiopancreatography, from training through independent practice. Gastroenterology. 2018 Nov;155(5):1483-1494.e7. doi: 10.1053/j.gastro.2018.07.024. Epub 2018 Jul 26.

Afify A, Huang EC, Jeong M, Urayama S. Immunoisolation of Pancreatic Epithelial Cells from Endoscopic Ultrasound-guided Fine Needle Aspirates with Magnetic Beads for Downstream Molecular Application. Diagnostic Cytopathology. 2016 Jan;44(1):32-8.  doi:10.1002/dc.23383. Epub 2015 Oct 15.

Ames E, Canter RJ, Grossenbacher SK, Mac S, Chen M, Smith RC, Hagino T, Perez-Cunningham J, Sckisel GD, Urayama S, Monjazeb AM, Fragoso RC, Sayers TJ, Murphy WJ. NK Cells Preferentially Target Tumor Cells with a Cancer Stem Cell Phenotype. J Immunol. 2015 Oct 15;195(8):4010-9.

Chen QX, Wang WP, Zeng S, Urayama S, Yu AM. A general approach to high-yield biosynthesis of chimeric RNAs bearing various types of functional small RNAs for broad applications. Nucleic Acids Res. 2015 Apr 20;43(7):3857-69. Epub 2015 Mar 23.

Urayama S, Azarm A, Khan R. Endoscopic ultrasound and pancreatic cancer: advancing the application of technology for early detection. J Interv Gastroenterol. 2015;5(2):68-74. 

Urayama S. Pancreatic cancer early detection: expanding higher-risk group with clinical and metabolomics parameters. World J Gastroenterol. 2015 Feb 14;21(6):1707-17.

Parikh DA, Durbin-Johnson B, Urayama S. Utility of serum CA19-9 levels in the  diagnosis of pancreatic ductal adenocarcinoma in an endoscopic ultrasound referral population. J Gastrointest Cancer. 2014 Mar;45(1):74-9.

Lin B, Urayama S, Saroufeem RM, Matthews DL, Demos SG. Establishment of rules for interpreting ultraviolet autofluorescence microscopy images for noninvasive detection of Barrett's esophagus and dysplasia. J Biomed Opt. 2012 Jan;17(1):016013.