Liver failure is a life-threatening condition in which your liver can no longer perform its job. A liver transplant at UC Davis Health can help you regain your health and quality of life.
Medically reviewed by Lea Matsuoka, M.D. on Aug. 17, 2023.
UC Davis Transplant Center has been a leader in advanced treatments for decades. We use the latest technology and methods available for liver transplantation. Our commitment to research means we are always working to improve your liver transplant experience.
Liver transplantation removes your failing liver and replaces it with a whole or partial healthy liver from someone else. There are two types of liver transplants.
A liver can regenerate itself, so your body only needs part of a donated liver. During a living donor transplantation, surgeons remove a piece of a donor’s liver. They remove your entire failing liver and transplant the piece of donor liver in your body. After the surgery, the donor’s remaining liver and your new liver will both regenerate.
Most donated livers come from deceased donors. During a deceased donor transplant, surgeons remove your liver and replace it with the donor’s liver. Sometimes, surgeons split a donor’s liver into two parts to help two recipients.
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If you have a living donor, your transplant care team will schedule you for surgery when you and your donor are ready. If you have a nonliving (deceased) donor, you will have surgery as soon as the liver is available. Your care coordinator will give you instructions on what to do before you go to the hospital for your procedure.
You will meet with your anesthesiologist and surgeon to discuss the details of your procedure. A nurse will start an IV in your arm to deliver fluids and anesthesia medication.
Transplant surgery requires general anesthesia. Your anesthesiologist will give you medicine in your IV to put you in a deep sleep. You will not be awake or feel pain during surgery. Your anesthesiologist will watch your blood pressure, breathing and heart rate throughout your surgery.
You will stay in the intensive care unit (ICU) after your transplant surgery. Your transplant care team will watch your blood pressure and heart rate. You will have blood tests and imaging studies to check that your new liver is working. Your provider will prescribe immunosuppressant medications to stop your immune system from attacking your new liver.
Most liver transplant recipients go home around two weeks after surgery. Your transplant care team will give you instructions for home care before you leave the hospital.
You will take immunosuppressant medication for the rest of your life. It is important to take your medication exactly as prescribed. This helps ensure your body doesn’t reject your new liver.
You will need regular medical check-ups and tests after your transplant surgery to ensure your new liver stays healthy.
Your provider will tell you when you can return to work and other activities. Many transplant recipients resume normal activity within a few months.
Contact your surgeon immediately if you are not feeling well. Symptoms include abdominal swelling or worsening abdominal pain, fever, jaundice (yellowing of your skin or eyes), nausea, vomiting, and diarrhea.
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