Danielle E. Brown, M.D.
Assistant Professor
To see if Danielle E. Brown is accepting new patients, or for assistance finding a UC Davis doctor, please call 800-2-UCDAVIS (800-282-3284).
Department
Locations and Contact
Lawrence J. Ellison Ambulatory Care Center
Orthopaedic Surgery Clinic
4860 Y Street
Sacramento, CA 95817
Clinic Phone: 916-734-2700
Clinic Fax: 916-734-7137
UC Davis Comprehensive Cancer Center
UC Davis Comprehensive Cancer Center
2279 45th Street
Sacramento, CA 95817
Phone: 916-734-5959
Philosophy of Care
I aspire to treat the whole patient, not just the disease. I think it is important to consider the patient's beliefs and goals of care and come to a mutually agreeable decision on the best course of action. There is a such an emotional aspect to cancer care, and I aim to treat this aspect with just as much importance as the musculoskeletal ramifications. My goal is to treat every patient as if they were my own family member.
Clinical Interests
Dr. Brown is a fellowship trained orthopaedic oncologist, specializing in surgical treatment of both benign and malignant conditions of the musculoskeletal system. This includes bone and soft tissue sarcoma, metastatic bone disease, pediatric bone tumors, as well as benign soft tissue and bone lesions.
Research/Academic Interests
As a former NIH T32 scholar, Dr. Brown has made significant contributions to the field through her extensive publications on topics such as limb salvage endoprosthetic longevity and survival and periprosthetic joint infection. She also has research interests in cartilage tumors, and circulating tumor DNA, and is dedicated to resident education and curriculum development.
Division
Center/Program Affiliation
Undergraduate School
B.S., Physiological Science, University of California, Los Angeles, Los Angeles CA 2013
Medical School
M.D., Medicine, University of California, San Francisco, San Francisco CA 2017
Residency
Orthopaedic Surgery, University of California, Los Angeles, Los Angeles CA 2017-2023
Fellowship
Orthopaedic Oncology, Memorial Sloan Kettering Cancer Center, New York NY 2023-2024
Best Chief Resident Research Project Award, University of California Los Angeles Department of Orthopaedic Surgery Residency Graduation Efficacy of a perioperative surgical site, multimodal drug injection in pediatric patients with cerebral palsy undergoing hip surgery: a multi-center randomized controlled trial, 2023,
Andrea Cracchiolo, III, MD and Edward O Leventen MD Resident Research Award in Orthopaedic Surgery Platelet deficiency represents a modifiable risk factor for periprosthetic joint infection in a preclinical mouse model, 2022,
Second place, best paper award; Musculoskeletal Tumor Society Annual Meeting Antibiotic calcium sulfate beads lower bacterial burden and prevent infection in a mouse model of periprosthetic joint infection, 2021,
Best Resident Paper Award; Western Orthopaedic Association Stem Tip Location Impacts Survival to Aseptic Loosening of Cemented Distal Femoral Replacements, 2021,
Clinical Science Award; Orthopaedic Research and Education Foundation Technology-assisted Total Hip Arthroplasty: An Analysis of Utilization Trends in the United States, 2020,
Cevallos N, Zukotynski B, Greig D, Silva M, Thompson RM. The utility of virtual reality in orthopaedic surgical training. J Surg Educ. 2022 Jul 9;S1931-7204(22)00152-0. PMID: 35821110.
Trikha R, Greig D, Shi Brendan, Schroeder G, Kremen TJ Jr. Multicenter analysis of the epidemiology of injury patterns and return to sport in collegiate gymnasts. Ortho J Sports Med. 2023 Feb 24;11(2). PMID: 36860774.
Geiger EJ, Arnold MT, Hart CM, Greig D, Trikha R, Sekimura T, Eckardt JJ, Bernthal NM. What is the long-term survivorship of primary and revision cemented distal femoral replacements for limb salvage of patients with sarcoma? Clin Orthop Relat Res. 2022 Aug 8. PMID: 35943730.
Arnold MT, Geiger EJ, Hart C, Greig D, Trikha R, Sekimura T, Eckardt JJ, Bernthal NM. Is high-dose radiation therapy associated with early revision due to aseptic loosening in patients with sarcoma of the lower extremities reconstructed with a cemented endoprosthesis? Clin Orthop Relat Res. 2022 Aug 17. PMID: 35977001.
Kendal JK, Hamad CD, Abbott AG, Greig D, Trikha R, Christ AB, Wessel LE, Puloski SKT, Monument MJ, Bernthal NM. What are the indications and survivorship of tumor endoprosthetic reconstructions for patients with extremity metastatic bone disease? J Surg Oncol. 2023 Jun;127(7):1196-1202. PMID: 36929601.
Trikha RT, Greig D, Olson TE, Kendal JK, Geiger EJ, Wessel L, Eckardt JJ, Bernthal NM. Proximal femur replacements for an oncologic indication offer a durable endoprosthetic reconstruction option: a 40-year experience. Clin Orthop Relat Res. 2023 Jul 14. PMID: 37458708.
Trikha RT, Greig D, Sekimura T, Geiger EJ, Wessel L, Eckardt JJ, Bernthal NM. The microbial profile of infected endoprosthetic reconstructions after wide excision for patients with musculoskeletal tumors: A call for pathogen-based practices. J Surg Oncol. 2023 Aug 23. PMID: 37610049.
Greig D, Sun C, Moon B, Swaroop V, Thompson RM. Efficacy of a perioperative surgical site, multimodal drug injection in pediatric patients with cerebral palsy undergoing hip surgery: a multi-center randomized controlled trial. J Bone and Joint Surg Am. 2024 Nov-Dec. PMID: 39140418.
Greig D, Trikha R, Kendal JK, Wessel L, Eckardt JJ, Bernthal NM. The prognostic impact of pathologic fracture in patients who undergo limb salvage and endoprosthetic reconstruction for bone sarcomas of the extremity. Clin Orthop Relat Res. Submitted September 2024.
Greig D, Saoud C, Antonescu CR, Wexler LH, Bartlett EK, Morris CD. Orthopaedic hardware-associated sclerosing rhabdomyosarcoma. JAAOS. Accepted for publication March 2025.