Sanchita Bhatnagar, Ph.D.
Associate Professor
Sanchita Bhatnagar is not currently accepting new patients. For assistance finding a UC Davis doctor, please call 800-2-UCDAVIS (800-282-3284).
Locations and Contact
Research/Academic Interests
The Bhatnagar research program is at the forefront of advancing scientific discovery, pioneering innovative approaches to unravel the complexities of epigenetic regulation in gene expression. By harnessing human disease models, the team translates fundamental insights into impactful advances for human health. The Bhatnagar laboratory remains dedicated to creating transformative tools, reagents, and therapeutics that tackle critical, unmet needs in medical research—particularly in the areas of childhood neurodevelopmental disorders and breast cancer. Through a spirit of collaboration and relentless curiosity, the laboratory aims to make a lasting difference in the lives of patients and contribute meaningfully to the broader scientific community.
Division
Medical Microbiology and Immunology
Center/Program Affiliation
• Oncogenic TRIM37 links chemoresistance and metastatic fate in triple negative breast cancer. Przanowski P, Lou S, Mondal T, Djiake R, Conlan C, Shivange G, Xing K, Morris B, Lehmann-Che J, Mayo M, Tushir-Singh J and Bhatnagar S*. Cancer Res. 2020 Nov 1;80(21):4791-4804. PMID: PMC7731897.
• The TRIM37 variant rs57141087 contributes to triple-negative breast cancer outcomes in Black women. Tihagam RD, Lou S, Zhao Y, Liu KS, Singh AT, Koo BI, Przanowski P, Li J, Huang X, Li H, Tushir-Singh J, Fejerman L, Bhatnagar S*. EMBO Reports. 2025. 2025 Jan;26(1):245-272. PMID: 39614126.
• Song Lou, Rachisan DJiake Tihagam, Urszula N. Wasko, Zaffar Equbal, Sanjay Venkatesan, Klaudia Braczyk, Piotr Przanowski, Bon Il Koo, Ilyas Saltani, Arjun Tushir Singh, Shibi Likhite, Samantha Powers, George M. P. R. Souza, Robert A Maxwell, Jun Yu, Lihua J. Zhu, Mark Beenhakker, Stephen B. G. Abbott, Zhipeng Lu, Michael R. Green, Kathrin C. Meyer, Jogender Tushir-Singh, and Bhatnagar S*. Targeting microRNA-dependent control of X chromosome inactivation improves the Rett Syndrome phenotype. Nature Communications. 2025
• Przanowski P, Wasko U, Zheng Z, Yu J, Zhu LJ, McConnell MJ, Tushir-Singh J, Green MR and Bhatnagar S*. Pharmacological reactivation of inactive X-linked Mecp2 in cerebral cortical neurons of living mice: implications for Rett syndrome therapeutics. Proc Natl Acad Sci U S A. 2018 Jul 16. pii: 201803792. doi: 10.1073/pnas.1803792115. PMCID: PMC30012595.