Structural Birth Defects | Pediatrics

Pediatrics

Structural Birth Defects

Structural birth defects (also called fetal structural abnormalities) can lead to disabilities and may be life-threatening. Our fetal care team offers advanced services for your family throughout pregnancy.

Medically reviewed by Amy Powne, R.N. on Nov. 06, 2023.

Pregnant woman looking at an ultrasound

Advanced Care for Fetal Structural Abnormalities

Structural birth defects occur while a baby forms in the womb (in utero). These changes include congenital heart defects, clubfoot, spina bifida and other conditions.

Fetal medicine specialists in our Fetal Care and Treatment Center expertly diagnose structural birth defects during pregnancy. In rare instances, we can intervene while your baby is still in the womb. Most structural birth defects require treatment after birth.  

Our Difference

Team of Specialists

You and your unborn baby receive dedicated care. Our fetal medicine specialists work closely with your OB-GYN (who may specialize in high-risk pregnancies) and newborn experts (neonatologists). Your family also receives care, guidance and support from nurse coordinators, genetic counselors, social workers and other care team members.

award_star
Highest Level of Newborn Care

Newborns with structural birth defects often need advanced medical care or surgery. Our level 4 neonatal intensive care unit (NICU) provides the highest level of care for your baby.

biotech
Innovative Research

Our fetal specialists are dedicated to caring for babies diagnosed with birth defects, as well as improving diagnostic tests and treatments. We’re currently spearheading a world-renowned spina bifida clinical trial. The CuRe Trial focuses on a promising new treatment that combines fetal surgery and stem cell therapy.

family_history

What Are Structural Birth Defects?

Structural birth defects affect how a baby’s body forms while in the womb. These fetal structural abnormalities may affect a child’s organs, spine, limbs or facial features.

Types of Structural Birth Defects

Gastroschisis and Abdominal Wall Defects

Gastroschisis occurs when a baby’s abdominal wall doesn’t fully close. The opening allows organs like the intestines to form outside their body. A baby undergoes a procedure after birth to put the organs back in the abdomen and close the opening.

Cleft Lip and Cleft Palate

Cleft lip occurs when a baby’s lip doesn’t form completely. A cleft palate happens when the roof of the mouth (palate) doesn’t form completely and there’s an opening in the palate. A baby may have one or both conditions. The UC Davis Children’s Hospital Cleft and Craniofacial Team offers expert care, including surgery, to correct these structural changes.

Congenital Heart Defects

Congenital heart defects are the most common structural birth defect. These are changes in the shape or structure of a baby’s heart. These changes often affect how well the heart functions. We offer advanced fetal cardiology services.

Clubfoot and Limb Changes

Some babies have limbs that don’t form completely. Others have a foot that turns inward (clubfoot) because the tendons (tissues) that connect muscle to bone are too short. Our pediatric orthopedic surgeons expertly treat clubfoot and other limb issues.

Spina Bifida (Myelomeningocele)

Spina bifida (myelomeningocele) is a neural tube defect that affects the formation of a baby’s spine. Part of a baby’s spinal cord comes through an opening in the spine that didn’t close. Your unborn baby may benefit from a clinical trial that combines fetal surgery with stem cell therapy.

list_alt

Causes and Risk Factors of Structural Birth Defects

Most structural birth defects occur for no known reason. Some birth defects run in families.

A gene change (mutation) can affect how a baby’s body develops in the womb. Some gene changes are passed from parent to child. Others happen unexpectedly.

These factors may increase the risk of structural birth defects:

Age

Being pregnant at age 35 or older may increase risk.

Environmental Factors

Exposure to certain chemicals or the use of some medications may make birth defects more likely.

Health Conditions and Infections

Having type 1 diabetes or type 2 diabetes may increase risk. Bacterial infections or viral infections during pregnancy are also risk factors.

Substance Use

Drinking alcohol, smoking or substance abuse during pregnancy may lead to birth defects.

"Congenital heart defects and critical CHDs," March of Dimes, https://www.marchofdimes.org/find-support/topics/planning-baby/congenital-heart-defects-and-critical-chds

"Birth defects and your baby," March of Dimes, https://www.marchofdimes.org/find-support/topics/planning-baby/birth-defects-and-your-baby

"What are birth defects?" Centers for Disease Control and Prevention (CDC), https://www.cdc.gov/ncbddd/birthdefects/facts.html

Request an Appointment

As Sacramento's No. 1 hospital, you'll benefit from unique advantages in primary care and specialty care. This includes prevention, diagnosis and treatment options from experts in 150 specialties.

Referring Physicians

To refer a patient, you can submit an electronic referral form or call.

family_restroom

Patients

For questions and appointment information

Awards and Recognitions
PreviousNext
USNWR Best Hospital badge

Ranked among the nation’s best hospitals

A U.S. News & World Report best hospital in cancer, cardiology, heart & vascular surgery, diabetes & endocrinology, ENT, geriatrics, neurology & neurosurgery, orthopedics, and pulmonology & lung surgery.

Learn more
US News & World Report best Children’s Hospital badge

Ranked among the nation’s best children’s hospitals

U.S. News & World Report ranked UC Davis Children’s Hospital among the best in neonatology, nephrology, orthopedics*, pediatric & adolescent behavioral health, and pulmonology & lung surgery. (*Together with Shriners Children’s Northern California)

Learn more
USNWR best regional hospital badge

Ranked Sacramento’s #1 hospital

Ranked Sacramento’s #1 hospital by U.S. News, and high-performing in back surgery, COPD, colon cancer surgery, gynecological cancer surgery, heart attack, heart failure, hip fracture, kidney failure, leukemia, lymphoma & myeloma, lung cancer surgery, pneumonia, prostate cancer surgery, stroke, TAVR, and gastroenterology & GI surgery.

Learn more
Magnet designation badge

The nation’s highest nursing honor

UC Davis Medical Center has received Magnet® recognition, the nation’s highest honor for nursing excellence.

Learn more
NCI badge

World-class cancer care

One of ~56 U.S. cancer centers designated “comprehensive” by the National Cancer Institute.

Learn more
HEI LGBTQ badge

A leader in health care equality

For the 13th consecutive year, UC Davis Medical Center has been recognized as an LGBTQ+ Healthcare Equality Leader by the educational arm of America’s largest civil rights organization.

Learn more
See more