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Vitiligo | Dermatology

Dermatology

Vitiligo

We are one of the few vitiligo clinics in the U.S dedicated to delivering expert diagnosis, personalized treatment, phototherapy, surgical care and access to clinical trials.

Medically reviewed by Victor Huang on June 12, 2026.

Hands with vitiligo.

What Is Vitiligo?

Vitiligo is a chronic skin condition in which patches of skin lose their pigmentation (color). This occurs when melanocytes, the cells that make your skin’s pigment, stop working due to autoimmune reactions.

The UC Davis Health Vitiligo Clinic provides specialized, personalized care for individuals living with vitiligo. Our team develops tailored treatment plans that may include medical therapies, phototherapy and surgical options based on each patient's goals and disease characteristics. As an active center for clinical research, we also offer access to innovative clinical trials and emerging therapies.

Symptoms of Vitiligo

Everyone’s vitiligo story is unique, and your symptoms may be different from someone else’s.

Skin Symptoms

Vitiligo can cause areas of skin to lose their pigment (color). Some patches are small and stay the same size for years, while others may get larger or spread. Vitiligo skin patches look different on everyone, and may appear:

  • On any part of the body, including the face, arms, legs and hands
  • Round, oval or linear with obvious borders
  • Symmetrical (both sides of your body)
  • White or lighter than your natural skin

Non-Skin Symptoms

Vitiligo can affect more than your skin. Some people with this condition may experience:

  • Emotional stress
  • Hearing loss
  • White or gray patches of hair
  • A higher susceptibility to other autoimmune conditions
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Vitiligo Causes and Risk Factors

Vitiligo is an autoimmune disease where your immune system mistakenly attacks pigment-making cells in your skin. Certain things increase your risk of developing vitiligo or making symptoms worse, including:

Autoimmune Diseases

You have a higher risk of developing vitiligo if you have other autoimmune conditions, such as Addison’s disease, psoriasis, lupus or rheumatoid arthritis.

Chemicals

Certain chemicals used in factories and skin-lightening products can cause a loss of pigment in your skin.

Family History

You have a higher risk of having vitiligo if you have biological relatives with the condition.

Skin Injury

Cuts, scrapes, burns or sunburn can sometimes trigger patches of vitiligo.

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Vitiligo Diagnosis

Health care providers do not fully understand what causes all autoimmune and connective tissue disorders. Some likely causes include:

Physical Exam

Your doctor will look for certain features that indicate vitiligo, such as the appearance of the patches. They may also ask you about other health conditions you have, your family history and when the patches appeared.

Wood’s Light Exam

This painless exam involves using a special light that can distinguish vitiligo from other skin conditions. It can also reveal patches that are not yet visible in normal light.

Biopsy

Your doctor may take a small sample of your skin and examine it under a microscope if other tests do not provide a clear diagnosis.

Blood Tests

Your provider may order blood tests to check for other autoimmune conditions that can occur with vitiligo.

Vitiligo Treatments

Our Vitiligo Clinic is one of only a few nationwide exclusively focused on vitiligo. Our vitiligo experts are board-certified dermatologists with advanced training and experience treating vitiligo.

Vitiligo treatment can slow or prevent the progression of patches and depigmented skin already affected. Our specialists consider your health needs and goals before creating a personalized treatment plan, which may include:

Medications

Topical (applied to the skin) medications can restore pigment in vitiligo. Systemic (internal) medications, such as pills, can slow the progression of vitiligo that is spreading rapidly.

Excimer Laser Therapy

The excimer laser delivers painless excimer light directly to vitiligo patches to restore color. This approach, which is not widely available, targets only the patches, leaving healthy skin unexposed to UV light. Our specialists have extensive experience using this equipment to achieve the best possible results.

Phototherapy (Light Therapy)

During phototherapy, you sit in a booth that emits UVB light, which signals your skin to produce pigment. This treatment is particularly effective for people with widespread vitiligo affecting large areas of the body. At UC Davis Health, we use state-of-the-art phototherapy equipment. Our dermatologists have specialized training in using light therapy for vitiligo.

Miniature Punch Grafting (MPG)

We may recommend miniature punch grafting if vitiligo does not respond to medications or light therapy. Your dermatologist uses a small tool to remove tiny pieces of healthy tissue from another part of your body. Then, they carefully transplant the tissue onto the vitiligo patches. Over time, the pigmented cells spread and cover the area.

Depigmentation

Depigmentation involves applying a special cream that removes pigment from your skin. Over several months, the skin on the rest of your body begins to match the vitiligo patches. This change in your skin color is permanent, so our specialists carefully discuss whether this treatment is right for you.

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Preventing Vitiligo

You cannot prevent vitiligo, and if you have this condition, you didn’t do anything “wrong.” You can help keep your skin healthy if you:

Avoid Sun Exposure

UV rays darken your pigmented skin and make vitiligo patches more obvious. Vitiligo patches are also more susceptible to sun damage and sunburn which can cause the spots to spread.

Protect From Injuries

You can’t avoid every accident or injury to your skin. But you can help prevent new patches from developing if you wear protective gloves when working with your hands. Also take extra care when cooking to avoid burns.

About

70MPeople worldwide have vitiligo.

Source: Vitiligo Foundation: Vitiligo Facts

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