Patricia M. Applegate, M.D., F.A.C.C.





Internal Medicine


  • Professor


To see if Patricia M. Applegate is accepting new patients, or for assistance finding a UC Davis doctor, please call 800-2-UCDAVIS (800-282-3284).

Lawrence J. Ellison Ambulatory Care Center

4860 Y St., Suite 0200
Sacramento, CA 95817
Driving Directions

Primary Phone:

Additional Phone Numbers

Clinic Phone: 916-734-3761
Clinic Fax: 916-734-6474
Clinic Referral Phone: 916-734-5678
Physician Referrals: 800-4-UCDAVIS (800-482-3284)


Cardiovascular Medicine

Center/Program Affiliation

Cardiovascular Services


M.D., University of Southern California, Los Angeles CA 1980

B.S., University of Nevada, Reno NV 1975

Internship: Internal Medicine, Loma Linda University Medical Center, Loma Linda CA


Internal Medicine, Loma Linda University Medical Center, Loma Linda CA 1980-1983


Cardiology, Loma Linda University Medical Center, Loma Linda CA 1983-1985

Cardiology Echocardiography, Mayo Graduate School of Medicine, Rochester MN 1985-1986

Board Certifications

American Board of Internal Medicine,

American Board of Internal Medicine, Cardiovascular Disease,

National Board of Echocardiography,

Professional Memberships

American College of Cardiology

American Society of Echocardiography

Select Recent Publications

Applegate II RL, Applegate PM, Cannesson M, Peiris P, Ladlie BL, Torp K. Multicenter comparison of three intraoperative hemoglobin trend monitoring methods. J Clin Monit Comput. 2020 Oct;34(5):883-892. doi:10.1007/s10877-019-00428-3. Epub 2019 Dec 3. Erratum in: J Clin Monit Comput. 2020 Jul 31;: PMID:31797199.

Huang L, Applegate II RL, Applegate PM, Gong L, Ocak U, Boling W, Zhang JH. Inhalation of high-concentration hydrogen gas attenuates cognitive deficits in a rat model of asphyxia induced-cardiac arrest. Med Gas Res. 2019 Jul-Sep;9(3):122-126. doi:10.4103/2045-9912.266986. PMID:31552874.

Huang L, Applegate RL 2nd, Applegate PM, Boling W, Zhang JH. Inhalation of high concentration hydrogen gas improves short-term outcomes in a rat model of asphyxia induced-cardiac arrest. Med Gas Res. 2018 Sep 25;8(3):73-78. doi:10.4103/2045-9912.241063. PMID:30319760.

Applegate PM, Boyd WD, Applegate II RL, Liu H. Is it the time to reconsider the choice of valves for cardiac surgery: mechanical or bioprosthetic? J Biomed Res. 2017 Sep 26;31(5):373-376. doi:10.7555/JBR.31.20170027. PMID:28958994.

Patuszynski D, Applegate PM. Suspected Clozapine-Induced Cardiomyopathy and Heart Failure With Reduced Ejection Fraction. Fed Pract. 2017 Apr;34(4):20-22. PMID:30766269.

Applegate RL 2nd, Dorotta IL, Wells B, Juma D, Applegate PM. The Relationship Between Oxygen Reserve Index and Arterial Partial Pressure of Oxygen During Surgery. Anesth Analg. 2016 Sep;123(3):626-33. doi:10.1213/ANE.0000000000001262. PMID:27007078.

Mangus DB, Huang L, Applegate PM, Gatling JW, Zhang J, Applegate RL 2nd. A systematic review of neuroprotective strategies after cardiac arrest: from bench to bedside (Part I - Protection via specific pathways). Med Gas Res. 2014 May 1;4:9. doi:10.1186/2045-9912-4-9. PMID:24808942.

Applegate PM, Applegate II RL. Imaging of Solid and Gaseous Materials. Reich, Fischer, Kaplan (eds). Perioperative Transesophageal Echocardiography: A Companion To Kaplan's Cardiac Anesthesia, Expert Consult Premium Edition, Elsevier. 2014.

Applegate PM, Applegate RL. Perioperative Transesophageal Echocardiography. Konstadt, Oka, Nanda (eds). TEE on DVD, Lippincott Williams & Wilkins. 2003.

Larsen RL, Applegate PM, Dyar DA, Ribeiro PA, Fritzsche SD, Mulla NF, Shirali GS, Kuhn MA, Chinnock RE, Shah PM. Dobutamine stress echocardiography for assessing coronary artery disease after transplantation in children. J Am Coll Cardiol. 1998 Aug;32(2):515-20. doi:10.1016/s0735-1097(98)00260-5. PMID:9708485.