Vitiligo

Vitiligo is a condition that causes skin to lose its color, leading to the development of white patches on your skin. While vitiligo is not harmful to your physical health, it can significantly affect the way you look and how you feel about your appearance. Many people with vitiligo experience emotional and social challenges as they adapt to the changes in their skin.

At UC Davis Health, we recognize that treating vitiligo goes beyond improving skin tone. It’s also about supporting your overall well-being and self-confidence. Our board-certified dermatologists use the most advanced diagnostic tools and therapies available, including light-based treatments, topical medications and innovative options such as excimer laser therapy.

This chronic skin disorder occurs when the skin loses the cells responsible for producing melanin, the pigment that gives skin its color. As a result, white patches can appear anywhere on the body, including the face, inside the mouth and even the genitals. In some cases, hair growing in affected areas may also turn white. Although vitiligo can change the way your skin and hair look, it is not contagious and does not pose a threat to your overall health.

Causes of Vitiligo

Vitiligo is an autoimmune condition in which the immune system mistakenly attacks the skin’s pigment-producing cells. You may be more likely to develop vitiligo if you have:

Family History of Vitiligo 

Vitiligo is a condition that can be inherited. Our genomic medicine counselors can help you understand this risk.

Autoimmune Disease

People who have one of these autoimmune diseases are more prone to vitiligo:

• Alopecia (hair loss)
• Diabetes
• Rheumatoid arthritis
• Thyroid disease 

How you feel about your appearance matters. We get that. While most dermatologists are familiar with vitiligo, we have a unique focus on helping people affected by this condition. Your care includes:

Specialty Vitiligo Clinic 

Our Vitiligo Clinic is one of approximately a dozen nationwide exclusively focused on vitiligo. Our vitiligo experts, Victor Huang, M.D., and Oma Agbai, M.D., are board-certified dermatologists with advanced training and experience treating vitiligo and other skin disorders.

Quality Hospital Care

Surgical treatments for vitiligo take place on an outpatient basis, meaning you go home the same day. You receive local anesthesia to numb the treatment area. Complications are extremely rare. If a problem develops, you have the benefit of being at UC Davis Medical Center. The U.S. News & World Report rates our hospital as the best in Sacramento and among the top 10 in California.

New Therapies

You may be able to try promising new therapies through our involvement in dermatology research and clinical trials. Our physicians are dedicated to finding better ways to treat vitiligo.

Care for All Ages

Vitiligo often develops before you turn 21 and can show up during childhood. We provide care for children and adults who have the disorder.

Patient Registry

We maintain a national registry that documents the effectiveness of vitiligo treatments. Physicians at UC Davis Health and across the country use this registry to customize the best treatment plan for each person’s unique situation.  

People with vitiligo often have other autoimmune diseases. Vitiligo also increases the risk of hearing or vision loss. Our team of board-certified dermatologists partner with other UC Davis Health physicians to meet all your health care needs. You may receive additional care from specialists in:

• Audiology (hearing)
• Endocrinology (diabetes and thyroid diseases)
• Hair Disorders Clinic (alopecia or hair loss)
• Ophthalmology (vision)
• Rheumatology-Dermatology Clinic (rheumatoid arthritis)

Every case of vitiligo is unique, and people respond to treatments in different ways. While there is no cure, a variety of therapies can help restore skin color and create a more even skin tone. At UC Davis Health, we tailor each treatment plan to your individual needs, ensuring you receive the approach that works best for you.

Our vitiligo treatments include:

• Topical and Systemic Medications
• Excimer Laser Therapy
• Phototherapy (Light Therapy)
• Miniature Punch Grafting
• Depigmentation

Topical and Systemic Medications

Topical medications (applied directly to the skin) may bring back skin color when vitiligo first appears. These ointments are most effective on small patches of skin on the face and neck.

Systemic medications taken orally or intravenously can slow or stop rapidly progressing vitiligo.

Treatments include:

• Corticosteroid creams
• Immunosuppressants containing tacrolimus or pimecrolimus (calcineurin inhibitors) to suppress an overactive immune system
• Systemic oral steroids 

Excimer Laser Therapy

Our physicians use an excimer laser system to direct a highly focused beam of ultraviolet (UV) light onto targeted areas of skin. While most private practices don’t offer this advanced technology, our status as a large medical center gives you access to it.

Benefits of excimer laser therapy include:

• More precise laser beam focus than phototherapy (light therapy), which exposes the entire body to UV light
• Minimal UV light exposure to healthy skin, which lowers the risk of skin cancer and premature aging
• Up to 70% of people see improvements in skin color after receiving twice-weekly treatments over a period of six months

Phototherapy (Light Therapy)

This treatment involves whole-body exposure to UV light while you sit or stand in a phototherapy booth. We are phototherapy experts. As a large medical center, we have the advanced technology and expertise to offer this treatment.

About phototherapy:

• You may need twice-weekly sessions for a couple of months or up to one year.
• Your physician may combine this treatment with oral or topical medications, such as psoralen (a light-absorbing chemical) or corticosteroids.

Miniature Punch Grafting (MPG)

MPG involves removing healthy circles of skin tissue from the buttocks or thighs. Doctors then transfer, or graft, the pigmented tissue onto white skin patches. The grafted area will resemble surrounding healthy pigmented skin. It is important to note that MPT moves tissue only (not skin cells), so the process does not stimulate pigment production.

During this outpatient procedure, your physician:

1. Numbs the skin with local anesthesia
2. Uses a device to remove small circular plugs of healthy, pigmented tissue
3. Uses the same device to remove small circular plugs of skin in the vitiligo area
4. Grafts the healthy skin tissue into the vitiligo patch with dissolvable stitches

Depigmentation

Depigmentation is often a last resort because it is permanent and extensive. Your physician may recommend this treatment if white vitiligo skin patches cover a significant portion of your body and other treatments do not work.

About depigmentation:

• The process involves applying a cream every day to remove color-producing pigment to even skin tones.
• Over time, treated skin blends with vitiligo patches.
• It may take up to a year to achieve the desired effect.

For more information or to schedule an appointment, please call 916-734-6111 or 800-770-9282.