Aijun Wang, Ph.D.

Aijun Wang, Ph.D.

Specialties

Surgery - General

Department

Surgery

Title

  • Vice Chair for Translational Research, Innovation and Entrepreneurship
  • Co-Director, Surgical Bioengineering Laboratory
  • Associate Professor, Department of Surgery
  • Chancellor's Fellow
  • Dean's Fellow in Entrepreneurship, School of Medicine

Reviews

Research II

4625 2nd Ave.
Sacramento, CA 95817
Driving Directions

Primary Phone:

Additional Phone Numbers

Clinic Phone: 916-703-0422
Clinic Fax: 916-703-0430
Physician Referrals: 800-4-UCDAVIS (800-482-3284)

Research/Academic Interests

Dr. Wang’s research focuses on developing innovative tools, technologies, and therapeutics that combine molecular, cellular, tissue, and biomaterial engineering to promote tissue regeneration and restore function. His lab engineers and develops stem cells, extracellular vesicles, and extracellular matrices to treat surgical conditions and diseases. His lab also conducts IND (Investigational New Drug) enabling studies and clinical trials in both companion animal patients and human patients. Serving as the School of Medicine Dean's fellow in entrepreneurship and Department of Surgery's Vice Chair for Translational Research, Innovation, and Entrepreneurship, Dr. Wang is an active researcher and strong advocate in promoting academic innovation and entrepreneurship.

Please click here to see Dr. Wang's lab web page.

Division

Pediatric Surgery

Center/Program Affiliation

Stem Cell Research Program

Education

M.S., Shandong University, Jinan, China 2003

Ph.D., Tsinghua University, Beijing, China 2007

B.S., Shandong Medical University, Jinan, China 2000

Fellowships

Department of Bioengineering, UC Berkeley, Berkeley CA 2008-2010

Berkeley Stem Cell Center, UC Berkeley, Berkeley CA 2010-2011

Professional Memberships

American Heart Association

Biomedical Engineering Society

International Fetal Medicine and Surgical Society

International Perinatal Stem Cell Society

International Society for Stem Cell Research

Tissue Engineering and Regenerative Medicine International Society

Honors and Awards

Winner of the KidneyX: Redesign Dialysis Phase 2 prize competition, the American Society of Nephrology (ASN) and the Department of Health and Human Services (HHS), 2020

Chancellor's Fellow, UC Davis, 2020

Dean's Team Award for Excellence in Research, UC Davis Health, 2020

Dean's Fellow in Entrepreneurship, UC Davis School of Medicine, 2018

NIH/NHLBI Technology Development Award, UC Center for Accelerated Innovation (UC-CAI), 2017

The Basil O'Connor Starter Scholar Research Award, the March of Dimes Foundation, 2016

Marquis Who's Who in America 2015 (69th Edition), Marquis Who's Who Publications, 2015

The Tony Phillips Research Award, the Children's Miracle Network (CMN), 2014

Best of ASH, American Society of Hematology 2014 Annual Meeting, 2014

Deloitte QB3 Award for Innovation, California Institute for Quantitative Bioscience (QB3), 2012

Winner of the Venture Lab Competition, Center for Entrepreneurship and Technology (CET), UC Berkeley, 2011

Tsinghua - Hengshanliangci Excellent Thesis Award, 2010

Select Recent Publications

Complete List of Published Work in MyBibliography: https://www.ncbi.nlm.nih.gov/sites/myncbi/aijun.wang.1/bibliography/53100355/public/?sort=date&direction=descending

Amorim RM, Clark KC, Walker NJ, Kumar P, Herout K, Borjesson DL, Wang A. Placenta-Derived Multipotent Mesenchymal Stromal/Stem Cells: A Promising Potential Cell-Based Therapy for Canine Inflammatory Brain Disease. Stem Cell Research & Therapy. 2020 Jul 22;11(1):304. PMID:32698861. doi:10.1186/s13287-020-01799-0.

Hao D, Fan Y, Xiao W, Liu R, Pivetti C, Walimbe T, Guo F, Zhang X, Farmer DL, Wang F, Panitch A, Lam KS, Wang A. Rapid endothelialization of small diameter vascular grafts by a bioactive integrin-binding ligand specifically targeting endothelial progenitor cells and endothelial cells. Acta Biomaterialia. 2020 May;108:178-193. PMID:32151698. doi:10.1016/j.actbio.2020.03.005.

Rose M, Gao K, Cortez-Toledo E, Agu E, Hyllen AA, Kelsey Conroy, Guangjin Pan, Nolta JA, Wang A*, Zhou P*. Endothelial cells derived from patients' induced pluripotent stem cells for sustained factor VIII delivery and the treatment of hemophilia A. STEM CELLS Transl Med. 2020 Jun;9(6):686-696. *Co-corresponding author. Featured as the front cover story (Volume 9, Number 6, June 2020). PMID:32162786. doi:10.1002/sctm.19-0261.

Hao D, Ma B, He C, Liu R, Farmer D, Lam K, Wang A. Surface Modification of Polymeric Electrospun Scaffolds via a Potent and High-Affinity Integrin α4β1 Ligand Improved the Adhesion, Spreading and Survival of Human Chorionic Villus-Derived Mesenchymal Stem Cells: A New Insight for Fetal Tissue Engineering. J Mater Chem B. 2020 Feb 26;8(8):1649-1659. PMID:32011618. doi:10.1039/c9tb02309g.

Kumar P, Becker JC, Gao K, Carney RP, Lankford L, Keller BA, Herout K, Lam KS, Farmer D, Wang A. Neuroprotective Effect of Placenta-derived Mesenchymal Stromal Cells: Role of Exosomes. The FASEB Journal. 2019 May;33(5):5836-5849. PMID:30753093. doi:10.1096/fj.201800972R.

Gao K, Kumar P, Cortez-Toledo E, Hao D, Reynaga L, Rose M, Wang C, Farmer D, Nolta J, Zhou J, Zhou P, Wang A. Potential long-term treatment of hemophilia A by neonatal co-transplantation of cord blood derived endothelial colony-forming cells and placental mesenchymal stromal cells. Stem Cell Research & Therapy. 2019 Jan 22;10(1):34. PMID:30670078. PMCID:PMC6341603. doi:10.1186/s13287-019-1138-8.

Phan J, Kumar P, Hao D, Gao K, Farmer D, Wang A. Engineering mesenchymal stem cells to improve their exosome efficacy and yield for cell-free therapy. Journal of Extracellular Vesicles. 2018 Sep 26;7(1):1522236. PMID:30275938. PMCID:PMC6161586. doi:10.1080/20013078.2018.1522236.

Hao D, Xiao W, Liu R, Kumar P, Li Y, Zhou P, Guo F, Farmer D, Lam K, Wang F, Wang A. Discovery and characterization of a potent and specific peptide ligand targeting endothelial progenitor cells and endothelial cells for tissue regeneration. ACS Chem Biol. 2017;12(4):1075–1086. PMID:28195700. doi:10.1021/acschembio.7b00118.

Wang A*, Brown EG, Lankford L, Keller BA, Pivetti CD, Sitkin NA, Beattie MS, Bresnahan JC, Farmer DL. Placental Mesenchymal Stromal Cells Rescue Ambulation in Ovine Myelomeningocele. Stem Cells Translational Medicine. 2015 Jun;4(6):659-69. *Corresponding author. PMID:25911465. PMCID:PMC4449103 doi:10.5966/sctm.2014-0296.

Tang Z/Wang A (Co-first author), Yan Z, Liu B, Chu J, Helms J, Li S. Differentiation of Multipotent Vascular Stem Cells Contributes to Vascular Diseases. Nature Communications. 2012;3:875. (Highlighted in Nature, 486, 9). PMID:22673902. PMCID:PMC3538044.